A genome-wide linkage analysis of alcoholism on microsatellite and single-nucleotide polymorphism data, using alcohol dependence phenotypes and electroencephalogram measures

BMC Genetics

Volumn 6, Issue SUPPL.1, 2005, Pages

  Zhang, Chun ^a   Cawley, Simon ^a   Liu, Guoying ^b   Cao, Manqui ^a   Gorrell, Harley ^b   Kennedy, Giulia C ^a  

^a Thermo Fisher Scientific   (United States)

^b CIS Enterprise Data Group   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLISM; ARTICLE; CHROMOSOME 10; CHROMOSOME 6; CHROMOSOME 7; CHROMOSOME ANALYSIS; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; FAMILY STUDY; GENE LOCUS; GENE MAPPING; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MICROSATELLITE MARKER; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; WORKSHOP; CHROMOSOME MAP; ELECTROENCEPHALOGRAPHY; GENETIC ASSOCIATION; GENETICS; PATHOPHYSIOLOGY;

MICROSATELLITE DNA;

ALCOHOLISM; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 7; ELECTROENCEPHALOGRAPHY; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICROSATELLITE REPEATS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 30344449954     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-6-S1-S17     Document Type: Article

References (22)

1. Edenberg HJ: The collaborative study on the genetics of alcoholism: an update. Alcohol Res Health 2002, 26:214-218.
2. Feighner JP, Robins E, Guze SB, Woodruff RA Jr, Winokur G, Munoz R: Diagnostic criteria for use in psychiatric research. Arch Gen Psychiatry 1972, 26:57-63.
3. Foroud T, Edenberg HJ, Goate A, Rice J, Flury L, Koller DL, Bierut LJ, Conneally PM, Nurnberger JI, Bucholz KK, Li TK, Hesselbrock V, Crowe R, Schuckit M, Porjesz B, Begleiter H, Reich T: Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcohol Clin Exp Res 2000, 24:933-945.
4. Reich T, Edenberg HJ, Goate A, Williams JT, Rice JP, Van Eerdewegh P, Foroud T, Hesselbrock V, Schuckit MA, Bucholz K, Porjesz B, Li TK, Conneally PM, Nurnberger JI Jr, Tischfield JA, Crowe RR, Cloninger CR, Wu W, Shears S, Carr K, Crose C, Willig C, Begleiter H: Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet 1998, 81:207-215.
5. Ghosh S, Begleiter H, Porjesz B, Chorlian DB, Edenberg HJ, Foroud T, Goate A, Reich T: Linkage mapping of Beta 2 EEG waves via non-parametric regression. Am J Med Genet B Neuropsychiatr Genet 2003, 118:66-71.
6. Porjesz B, Almasy L, Edenberg HJ, Wang K, Chorlian DB, Foroud T, Goate A, Rice JP, O'Connor SJ, Rohrbaugh J, Kuperman S, Bauer LO, Crowe RR, Schuckit MA, Hesselbrock V, Conneally PM, Tischfield JA, Li TK, Reich T, Begleiter H: Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci USA 2002, 99:3729-3733.
7. Jones KA, Porjesz B, Almasy L, Bierut L, Goate A, Wang JC, Dick DM, Hinrichs A, Kwon J, Rice JP, Rohrbaugh J, Stock H, Wu W, Bauer LO, Chorlian DB, Crowe RR, Edenberg HJ, Foroud T, Hesselbrock V, Kuperman S, Nurnberger J Jr, O'Connor SJ, Schuckit MA, Stimus AT, Tischfield JA, Reich T, Begleiter H: Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: Implications for human brain dynamics and cognition. Int J Psychophysiol 2004, 53:75-90.
8. Botstein D, Risch N: Discovering genotypes underlying human phenotypes: past successes for Mendelian disease, future approaches for complex disease. Nat Genet 2003, 33(Suppl):228-237.
9. Risch NJ: Searching for genetic determinants in the new millennium. Nature 2000, 405:847-856.
10. Kruglyak L: The use of a genetic map of biallelic markers in linkage studies. Nat Genet 1997, 17:21-24.
11. Kennedy GC, Matsuzaki H, Dong S, Liu WM, Huang J, Liu G, Su X, Cao M, Chen W, Zhang J, Liu W, Yang G, Di X, Ryder T, He Z, Surti U, Phillips MS, Boyce-Jacino MT, Fodor SP, Jones KW: Large-scale genotyping of complex DNA. Nat Biotechnol 2003, 21:1233-1237.
12. O'Connell JR, Weeks DE: PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet 1998, 63:259-266.
13. Abecasis GR, Cherny SS, Cardon LR: The impact of genotyping error on family-based analysis of quantitative traits. Eur J Hum Genet 2001, 9:130-134.
14. Douglas JA, Boehnke M, Lange K: A multipoint method for detecting genotyping errors and mutations in sibling-pair linkage data. Am J Hum Genet 2000, 66:1287-1297.
15. John S, Shephard N, Liu G, Zeggini E, Cao M, Chen W, Vasavda N, Mills T, Barton A, Hinks A, Eyre S, Jones KW, Ollier W, Silman A, Gibson N, Worthington J, Kennedy GC: Whole-genome scan, in a complex disease, using 11,245 single-nucleotide polymorphisms: comparison with microsatellites. Am J Hum Genet 2004, 75:54-64.
16. Abecasis GR, Cherny SS, Cookson WO, Cardon LR: Merlin - rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet 2002, 30:97-101.
17. Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES: Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet 1996, 58:1347-1363.
18. Kong A, Cox NJ: Allele-sharing models: LOD scores and accurate linkage tests. Am J Hum Genet 1997, 61:1179-1188.
19. Lander ES, Green P: Construction of multilocus genetic linage maps in humans. Proc Natl Acad Sci U S A 1987, 84:2363-2367.
20. Lin DY, Zou F: Assessing genomewide statistical significance in linkage studies. Genet Epidemiol 2004, 27(3):202-214.
21. Schaid DJ, McDonnell SK, Wang L, Cunningham JM, Thibodeau SN: Caution on pedigree haplotype inference with software that assumes linkage equilibrium. Am J Hum Genet 2002, 71:992-995.
22. Schaid DJ, Guenther JC, Christensen GB, Hebbring S, Rosenow C, Hilker CA, McDonnell SK, Cunningham JM, Slager SL, Blute ML, Thibodeau SN: Comparison of microsatellites versus single-nucleotide polymorphisms in a genome linkage screen for prostate cancer-susceptibility loci. Am J Hum Genet 2004, 75:948-965.