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Volumn 28, Issue 14, 2005, Pages 1818-1822
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Metabolism of a novel antiangiogenic agent KR-31831 in rats using liquid chromatography-electrospray mass spectrometry
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Author keywords
KR 31831; LC MS; Metabolism; Rat
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Indexed keywords
AGENTS;
BIOCHEMISTRY;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
METABOLISM;
METABOLITES;
PHARMACOKINETICS;
ANTIANGIOGENIC AGENT;
ELECTROSPRAY MASS SPECTROMETRY;
METABOLIC ROUTES;
RATS;
PHENOLS;
4 [[(1H IMIDAZOL 2 YL)METHYL](4 CHLOROPHENYL)AMINO] 6 AMINO 2 (DIMETHOXYMETHYL) 2 METHYL 3,4 DIHYDRO 2H CHROMEN 3 OL;
4 [[(1H IMIDAZOL 2 YL)METHYL](4 CHLOROPHENYL)AMINO] 6 AMINO 2 (HYDROXYMETHYL) 2 METHYL 3,4 DIHYDRO 2H CHROMEN 3 OL;
ANGIOGENESIS INHIBITOR;
DRUG METABOLITE;
KR 31831;
N [(1H IMIDAZOL 2 YL)METHYL] 4 CHLOROBENZENAMINE;
N [4 [[(1H IMIDAZOL 2 YL)METHYL](4 CHLOROPHENYL)AMINO] 2 (DIMETHOXYMETHYL) 3 HYDROXY 2 METHYL 3,4 DIHYDRO 2H CHROMEN 6 YL]ACETAMIDE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ANIMAL EXPERIMENT;
ARTICLE;
CONTROLLED STUDY;
DRUG BILE LEVEL;
DRUG BLOOD LEVEL;
DRUG METABOLISM;
DRUG URINE LEVEL;
ELECTROSPRAY MASS SPECTROMETRY;
IN VITRO STUDY;
IN VIVO STUDY;
INCUBATION TIME;
LIQUID CHROMATOGRAPHY;
LIVER CELL;
LIVER MICROSOME;
MALE;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
ANGIOGENESIS INHIBITORS;
ANIMALS;
BENZOPYRANS;
BIOTRANSFORMATION;
CHROMATOGRAPHY, LIQUID;
HEPATOCYTES;
IMIDAZOLES;
MICROSOMES, LIVER;
RATS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
ANIMALIA;
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EID: 30344449481
PISSN: 16159306
EISSN: None
Source Type: Journal
DOI: 10.1002/jssc.200500159 Document Type: Article |
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Times cited : (4)
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References (7)
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