Sodium arsenite-induced inhibition of eukaryotic translation initiation factor 4E (eIF4E) results in cytotoxicity and cell death

Molecular and Cellular Biochemistry

Volumn 279, Issue 1-2, 2005, Pages 123-131

  Othumpangat, Sreekumar ^a   Kashon, Michael ^a   Joseph, Pius ^a  

^a NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Arsenic; Eukaryotic translation initiation factor 4E (eIF4E); Gene expression; Protection; Small interfering RNA (SiRNA); Toxicity; Ubiquitination

Indexed keywords

ARSENITE SODIUM; CYCLIN D1; INITIATION FACTOR 4E; MESSENGER RNA; SMALL INTERFERING RNA; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL LINE; CHO CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DEREGULATION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE TARGETING; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; POSTTRANSCRIPTIONAL GENE SILENCING; PROTEIN EXPRESSION; RNA BINDING; TRANSCRIPTION REGULATION; UBIQUITINATION; WESTERN BLOTTING;

ANIMALS; ARSENITES; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; EUKARYOTIC INITIATION FACTOR-4E; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SODIUM COMPOUNDS; TRANSFECTION; UBIQUITIN;

ANIMALIA; CRICETULUS GRISEUS; EUKARYOTA;

EID: 30344439511     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-005-8284-2     Document Type: Article

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