Mechanistic implications of the structure of the mixed-disulfide intermediate of the disulfide oxidoreductase, 2-ketopropyl-coenzyme M oxidoreductase/carboxylase

Biochemistry

Volumn 45, Issue 1, 2006, Pages 113-120

  Pandey, Arti S ^a   Nocek, Boguslaw ^a   Clark, Daniel D ^b   Ensign, Scott A ^b   Peters, John W ^a  

^a MONTANA STATE UNIVERSITY   (United States)

^b UTAH STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; CARBOXYLATION; CRYSTALLIZATION; PROTEINS; STABILIZATION; X RAY DIFFRACTION;

DISULFIDE OXIDOREDUCTASE; NADPH; PROTEIN CYSTEINE DISULFIDE; THIOETHER BOND;

STRUCTURAL ANALYSIS;

2 KETOPROPYL COENZYME M CARBOXYLASE; 2 KETOPROPYL COENZYME M OXIDOREDUCTASE; ACETOACETIC ACID; ACETONE; CARBON DIOXIDE; CARBOXYLASE; DISULFIDE OXIDOREDUCTASE; ENOLACETONE; FLAVOPROTEIN; MESNA; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; PYRIDINE; SULFIDE; UNCLASSIFIED DRUG;

ARTICLE; CARBOXYLATION; CHEMICAL BOND; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REDUCTION; STRUCTURE ANALYSIS; X RAY DIFFRACTION;

ACETOACETATES; BINDING SITES; CARBON DIOXIDE; CARBOXY-LYASES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DISULFIDES; DITHIOTHREITOL; ENZYME STABILITY; HYDROPHOBICITY; KETONE OXIDOREDUCTASES; MODELS, CHEMICAL; NADP; OXIDOREDUCTASES; SUBSTRATE SPECIFICITY;

EID: 30144446084     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051518o     Document Type: Article

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