Therapy-related myelodysplastic syndrome with inv(16)(p13q22) and I type CBFβ/MYH11 after autologous transplantation: Undetectable fusion transcript in pretransplant progenitor cells

Leukemia Research

Volumn 30, Issue 3, 2006, Pages 354-361

  Yamamoto, Katsuya ^a   Nishikawa, Shinichiro ^a   Minagawa, Kentaro ^a   Yakushijin, Kimikazu ^a   Okamura, Atsuo ^a   Matsui, Toshimitsu ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Autologous stem cell transplantation; I type CBF MYH11 fusion transcript; Inv(16)(p13q22); Non Hodgkin's lymphoma; Post transplant therapy related myelodysplastic syndrome

Indexed keywords

BUSULFAN; CISPLATIN; CORE BINDING FACTOR; CORE BINDING FACTOR BETA; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DOXORUBICIN; EPIRUBICIN; ETOPOSIDE; FLUDARABINE; FLUOROURACIL; MERCAPTOPURINE; METHYLPREDNISOLONE; MITOXANTRONE; MYOSIN HEAVY CHAIN; PREDNISOLONE; UNCLASSIFIED DRUG; VINCRISTINE;

ACUTE MYELOBLASTIC LEUKEMIA; ADULT; ANAMNESIS; ARTICLE; AUTOLOGOUS PERIPHERAL BLOOD STEM CELL TRANSPLANTATION; BONE MARROW BIOPSY; BONE MARROW CELL; CASE REPORT; CELL DAMAGE; CHROMOSOME 16; CHROMOSOME INVERSION; CORD BLOOD STEM CELL TRANSPLANTATION; DRUG DOSE REGIMEN; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; LABORATORY TEST; LARGE CELL LYMPHOMA; LYMPHOMA; MYELODYSPLASTIC SYNDROME; NONHODGKIN LYMPHOMA; NUCLEOTIDE SEQUENCE; PANCYTOPENIA; PRIORITY JOURNAL; REFRACTORY ANEMIA WITH EXCESS BLASTS IN TRANSFORMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TREATMENT OUTCOME; WHOLE BODY RADIATION;

CHROMOSOMES, HUMAN, PAIR 16; FEMALE; HEMATOPOIETIC STEM CELLS; HUMANS; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL, DIFFUSE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; ONCOGENE PROTEINS, FUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEM CELL TRANSPLANTATION; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS;

EID: 30144439910     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2005.08.001     Document Type: Article

References (20)

1. J. Pedersen-Bjergaard, M.K. Andersen, and D.H. Christiansen Therapy-related acute myeloid leukemia and myelodysplasia after high-dose chemotherapy and autologous stem cell transplantation Blood 95 2000 3273 3279
2. D.G. Gilliland, and J.G. Gibben Evaluation of the risk of therapy-related MDS/AML after autologous stem cell transplantation Biol Blood Marrow Transpl 8 2002 9 16
3. E. Abruzzese, J.E. Radford, J.S. Miller, J.J. Vredenburgh, P.N. Rao, and M.J. Pettenati Detection of abnormal pretransplant clones in progenitor cells of patients who developed myelodysplasia after autologous transplantation Blood 94 1999 1814 1819
4. D.M. Lillington, I.N.M. Micallef, E. Carpenter, M.J. Neat, J.A.L. Amess, and J. Matthews Detection of chromosome abnormalities pre-high-dose treatment in patients developing therapy-related myelodysplasia and secondary acute myelogenous leukemia after treatment for non-Hodgkin's lymphoma J Clin Oncol 19 2001 2472 2481
5. M.H. Weber, U. Wenzel, E. Thiel, and W.U. Knauf Chromosomal aberrations characteristic for sAML/sMDS are not detectable by random screening using FISH in peripheral blood-derived grafts used for autologous transplantation J Hematother Stem Cell Res 9 2000 861 865
6. M.M. Le Beau, R.A. Larson, M.A. Bitter, J.W. Vardiman, H.M. Golomb, and J.D. Rowley Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic- clinicopathological association N Engl J Med 309 1983 630 636
7. M. Dissing, M.M. Le Beau, and J. Pedersen-Bjergaard Inversion of chromosome 16 and uncommon rearrangements of the CBFB and MYH11 genes in therapy-related acute myeloid leukemia: rare events related to DNA-topoisomerase II inhibitors? J Clin Oncol 16 1998 1890 1896
8. M.K. Andersen, R.A. Larson, N. Mauritzson, S. Schnittger, S.C. Jhanwar, and J. Pedersen-Bjergaard Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an International Workshop Gene Chromosome Cancer 33 2002 395 400
9. P. Liu, S.A. Tarle, A. Hajra, D.F. Claxton, P. Marlton, and M. Freedman Fusion between transcription factor CBFβ/PEBP2β and a myosin heavy chain in acute myeloid leukemia Science 261 1993 1041 1044
10. R. Matsuoka, M.C. Yoshida, Y. Furutani, S. Imamura, N. Kanda, and M. Yanagisawa Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12 Am J Med Genet 46 1993 61 67
11. P.P. Liu, A. Hajra, C. Wijmenga, and F.S. Collins Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia Blood 85 1995 2289 2302
12. J.T. Reilly Pathogenesis of acute myeloid leukaemia and inv(16)(p13;q22): a paradigm for understanding leukaemogenesis? Br J Haematol 128 2004 18 34
13. ISCN F. Mitelman An international system for human cytogenetic nomenclature 1995 S. Karger Basel
14. B.A. van der Reijden, M. Lombardo, H.G. Dauwerse, R.H. Giles, D. Muhlematter, and M.J. Bellomo RT-PCR diagnosis of patients with acute nonlymphocytic leukemia and inv(16)(p13q22) and identification of new alternative splicing in CBFB-MYH11 transcripts Blood 86 1995 277 282
15. B.A. van der Reijden, L. de Wit, S. van der Poel, E.B. Luiten, M. Lafage-Pochitaloff, and N. Dastugue Identification of a novel CBFB-MYH11 transcript: implications for RT-PCR diagnosis Hematol J 2 2001 206 209
16. N. Grardel, C. Roumier, V. Soenen, J.L. Lai, I. Plantier, and C. Gheveart Acute myeloblastic leukemia (AML) with inv(16)(p13;q22) and the rare I type CBFβ-MYH11 transcript: report of two new cases Leukemia 16 2002 150 151
17. S.M. Hackwell, D.O. Robinson, J.F. Harvey, and F.M. Ross Identification of false-positive CBFβ/MYH11 RT-PCR results Leukemia 13 1999 1617 1619
18. B.A. van der Reijden, H.G. Dauwerse, R.H. Giles, S. Jagmohan-Changur, C. Wijmenga, and P.P. Liu Genomic acute myeloid leukemia-associated inv(16)(p13q22) breakpoints are tightly clustered Oncogene 18 1999 543 550
19. A.R. Mistry, C.A. Felix, R.J. Whitmarsh, A. Mason, A. Reiter, and B. Cassinat DNA topoisomerase II in therapy-related acute promyelocytic leukemia N Engl J Med 352 2005 1529 1538
20. B.A. van der Reijden, A. Hagemeijer, and M.H. Breuning Novel CBFB-MYH11 fusion transcripts or reverse transcription-polymerase chain reaction artifacts? Blood 87 1996 2605 2607