Responders to antidepressant drug treatment: A study comparing nefazodone, imipramine, and placebo in patients with major depression

Journal of Clinical Psychiatry

Volumn 57, Issue SUPPL. 2, 1996, Pages 15-18

  Cohn, Cal K ^a   Robinson, Donald S ^c   Roberts, Douglas L ^b   Schwiderski, Ute E ^b   O'Brien, Kathleen ^b   Ieni, John R ^b  

^a Cohn Center ^*  (United States)

^b BRISTOL MYERS SQUIBB   (United States)

^c Bristol Myers Squibb US P ^*

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; IMIPRAMINE; MONOAMINE OXIDASE INHIBITOR; NEFAZODONE; PLACEBO; SEROTONIN ANTAGONIST; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG SAFETY; FEMALE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SEXUAL DYSFUNCTION; TREATMENT OUTCOME;

ADULT; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; DEPRESSIVE DISORDER; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; IMIPRAMINE; MALE; PERSONALITY INVENTORY; PLACEBOS; PSYCHIATRIC STATUS RATING SCALES; TREATMENT OUTCOME; TRIAZOLES;

EID: 0029914873     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Eison AS, Eison MS, Torrente JR, et al. Nefazodone: preclinical pharmacology of a new anudepressant Psychopharmacology (Berl) 1990;26: 311-315
2. Preskor SH, Comparison of the tolerability of bupropion, fluoxetine, imipramine, nefazodone, paroxetine, sertraline, and venlafaxine. J Clin Psychiatry 1995;56(suppl 6): 12-21
3. Lipinski JF Jr, Mallya G, Zimmerman P, et al. Fluoxetine-induced akathisia: clinical and theoretical implications. J Clin Psychiatry 1989;50: 339-342
4. Edwards JG. Selective serotonin reuptake inhibitors: a modest though welcome advance in the treatment of depression. BMJ 1992:304: 1644-1645
5. Settle EC Jr. Antidepressant side effects: issues and options. J Clin Psychiatry Monograph 1992:10(1):48-61
6. Cunningham LA, Borison RL, Carman JS. et al. A comparison of venlafaxine, trazodone, and placebo in major depression. J Clin Psychopharmacol 1994;14:99-106
7. Sharpley AL, Walsh AES, Cowen PJ. Nefazodone - a novel antidepressant - may increase REM sleep. Biol Psychiatry 1992;31:1070-1073
8. Armitage R, Rush AJ, Trivedi M, et al. The effects of nefazodone on sleep architecture in depression. Neuropsychopharmacology 1994;30: 123-127
9. Rickels K, Schweizer E, Clary C, et al. Nefazodone and imipramine in major depression: a placebo-controlled trial. Br J Psychiatry 1994;164: 802-805
10. Fontaine R, Ontiveros A, Elie R, et al. A double-bund comparison of nefazodone, imipramine, and placebo in major depression. J Clin Psychiatry 1994;55:234-241
11. Rickels K, Robinson DS, Schweizer E, et al. Nefazodone: aspects of efficacy. J Clin Psychiatry 1995;56(suppl 6):43-46
12. Fawcert J, Marcus RN, Anton SF, et al. Response of anxiety and agitation symptoms during nefazodone treatment of major depression. J Clin Psychiatry 1995;56(suppl 6):37-42
13. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. Third Edition, Revised. Washington, DC: American Psychiatric Association; 1987
14. Klerman GL, Weissman MM, Frank E, et al. Evaluating drug treatments of depressive disorders. In: Prien RF, Robinson DS, eds. Clinical Evaluation of Psychotropic Drugs: Principles and Guidelines. New York, NY: Raven Press; 1994
15. Rush AJ, Gullion CM, Raskin A, et al. Assessment and measurement of clinical change. In: Prien RF, Robinson DS, eds. Clinical Evaluation of Psychotropic Drugs: Principles and Guidelines. New York. NY: Raven Press; 1994
16. Blum MH. Measuring response in treatment of depression [letter]. J Clin Psychiatry 1994;54:77
17. Guy W, ed ECDEU Assessment Manual for Psychopharmacology. Revised. US Dept Health. Education, and Welfare publication (ADM) 76-338. Rockville, Md: National Institute of Mental Health; 1976
18. US Food and Drug Administration. Coding Symbols for Thesaurus of Adverse Reaction Terms (COSTART). National Adverse Drug Reaction Dictionary. Rockville, Md: US Government Printing Office; 1989
19. Robinson DS, Prien RF. Clinical study design: critical issues. In: Bloom FE, Kupfer DJ, eds. Psychopharmacology The Fourth Generation of Progress. New York, NY: Raven Press: 1994