Dexamethasone reduces reintubation rate due to postextubation stridor in a high-risk paediatric population

Acta Paediatrica, International Journal of Paediatrics

Volumn 95, Issue 1, 2006, Pages 74-76

  Lukkassen, Ingrid M A ^a   Hassing, Marre B F ^b   Markhorst, Dick G ^b  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Airway obstruction; Dexamethasone; Extubation; Intubation; Stridor

Indexed keywords

ADRENALIN; DEXAMETHASONE; GLUCOCORTICOID;

ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG EFFECT; EXTUBATION; FEMALE; HIGH RISK POPULATION; HUMAN; INCIDENCE; INFANT; INTENSIVE CARE; INTUBATION; MALE; MEDICAL RECORD REVIEW; NEBULIZATION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROPHYLAXIS; RETROSPECTIVE STUDY; STRIDOR; TREATMENT INDICATION;

ANTI-INFLAMMATORY AGENTS; CHILD, PRESCHOOL; CROUP; DEXAMETHASONE; FEMALE; HUMANS; INFANT; INTUBATION, INTRATRACHEAL; MALE; RESPIRATORY SOUNDS; RETROSPECTIVE STUDIES;

EID: 29944445295     PISSN: 08035253     EISSN: 15023869     Source Type: Journal    
DOI: 10.1080/08035250500325066     Document Type: Article

References (12)

1. Kemper KJ, Benson MS, Bishop MJ. Predictors of postextubation stridor in paediatric trauma patients. Crit Care Med 1991;19:352-5.
2. Anene O, Meert KL, Uy H, Simpson P, Sarnaik AP. Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial. Crit Care Med 1996;24:1666-9.
3. Koka BV, Jeon IS, Andre JM, MacKay I, Smith RM. Postintubation croup in children. Anesth Analg 1977;56:501-5.
4. Tellez DW, Galvis AG, Storgion SA, Amer HN, Hoseyni M, Deakers TW. Dexamethasone in the prevention of postextubation stridor in children. J Pediatr 1991;118:289-94.
5. Harel Y, Vardi A, Quigley R, Brink L, Manning S, Levin D. Dexamethasone does not prevent post extubation stridor in pediatric patients who failed extubation due to stridor. Crit Care Med 1995;23(Suppl):A186.
6. Advanced Life Support Group. Advanced paediatric life support. 3rd ed. London: BMJ Books; 2000.
7. Miller RL, Cole RP. Association between reduced cuff leak volume and postextubation stridor. Chest 1996;110:1035-40.
8. Foland JA, Super DM, Dahdah NS, Mhanna MJ. The use of the air leak test and corticosteroids in intubated children: a survey of pediatric critical care fellowship directors. Respir Care 2002;47:662-6.
9. Mhanna MJ, Zamel YB, Tichy CM, Super DM. The "air leak" test around the endotracheal tube, as a predictor of postextubation stridor, is age dependent in children. Crit Care Med 2002;30:2639-43.
10. Shemie S. Steroids for anything that swells: dexamethasone and postextubation airway obstruction. Crit Care Med 1996;24:1613-4.
11. Markovitz BP, Randolph AG. Corticosteroids for the prevention of reintubation and postextubation stridor in pediatric patients: a meta-analysis. Pediatr Crit Care Med 2002;3:223-6.
12. Randolph AG, Wypij D, Venkataraman ST, Hanson JH, Gedeit RG, Meert KL, et al. Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial JAMA 2002;288:2561-8.