Preparation of bupleurum nasal spray and evaluation on its safety and efficacy

Chemical and Pharmaceutical Bulletin

Volumn 54, Issue 1, 2006, Pages 48-53

  Xie, Yueling ^a   Wei, Lu ^a,b   Cao, Shilei ^a   Jiang, Xinguo ^a   Yin, Ming ^b   Tang, Wenlu ^b  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Antipyretic effect; Essential oil; Nasal ciliotoxicity; Nasal spray; Radix Bupleuri

Indexed keywords

BUPLEURUM ROOT; COLICIN; DIETHYLENE GLYCOL MONOETHYL ETHER; ESSENTIAL OIL; POLYSORBATE 80; PROPYLENE GLYCOL; SOLUBILIZER; TRANSCUTOL P; TURPENTINE; TW 80; WATER;

ACUTE TOXICITY; AEROSOL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPYRETIC ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BODY TEMPERATURE; BUPLEURUM; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG ISOLATION; DRUG SAFETY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SYNTHESIS; FEMALE; FEVER; MALE; NONHUMAN; RABBIT; RAT; VISCOSITY;

ADMINISTRATION, INTRANASAL; AEROSOLS; ALGORITHMS; ANALGESICS, NON-NARCOTIC; ANIMALS; BUPLEURUM; CHEMISTRY, PHARMACEUTICAL; CILIA; ESCHERICHIA COLI; EXCIPIENTS; FEMALE; FEVER; MALE; NASAL MUCOSA; OILS, VOLATILE; PYROGENS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOLVENTS; TURPENTINE;

EID: 29844454642     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.54.48     Document Type: Article

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