Glucose metabolism and insulin therapy

Critical Care Clinics

Volumn 22, Issue 1, 2006, Pages 119-129

  Langouche, Lies ^a   Van Den Berghe, Greet ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

BLOOD GLUCOSE MONITORING; CLINICAL TRIAL; CRITICAL ILLNESS; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; INSULIN RESISTANCE; INSULIN TREATMENT; META ANALYSIS; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SYSTEMATIC REVIEW;

CRITICAL ILLNESS; GLUCOSE; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; OUTCOME ASSESSMENT (HEALTH CARE); STRESS;

EID: 29844454431     PISSN: 07490704     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ccc.2005.09.005     Document Type: Review

References (78)

1. K.C. McCowen, A. Malhotra, and B.R. Bistrian Stress-induced hyperglycemia Crit Care Clin 17 1 2001 107 124
2. A. Thorell, J. Nygren, and O. Ljungqvist Insulin resistance: a marker of surgical stress Curr Opin Clin Nutr Metab Care 2 1 1999 69 78
3. G. Van den Berghe, P. Wouters, and F. Weekers Intensive insulin therapy in critically ill patients N Engl J Med 345 19 2001 1359 1367
4. G. Van den Berghe, P.J. Wouters, and R. Bouillon Outcome benefit of intensive insulin therapy in the critically ill: insulin dose versus glycemic control Crit Care Med 31 2 2003 359 366
5. A. Rovlias, and S. Kotsou The influence of hyperglycemia on neurological outcome in patients with severe head injury Neurosurgery 46 2 2000 335 342
6. E. Jeremitsky, L.A. Omert, and C.M. Dunham The impact of hyperglycemia on patients with severe brain injury J Trauma 58 1 2005 47 50
7. D.C. Gore, D. Chinkes, and J. Heggers Association of hyperglycemia with increased mortality after severe burn injury J Trauma 51 3 2001 540 544
8. S. Yendamuri, G.J. Fulda, and G.H. Tinkoff Admission hyperglycemia as a prognostic indicator in trauma J Trauma 55 1 2003 33 38
9. A.M. Laird, P.R. Miller, and P.D. Kilgo Relationship of early hyperglycemia to mortality in trauma patients J Trauma 56 5 2004 1058 1062
10. G.V. Bochicchio, J. Sung, and M. Joshi Persistent hyperglycemia is predictive of outcome in critically ill trauma patients J Trauma 58 5 2005 921 924
11. S.E. Capes, D. Hunt, and K. Malmberg Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview Lancet 355 9206 2000 773 778
12. S.E. Capes, D. Hunt, and K. Malmberg Stress hyperglycemia and prognosis of stroke in nondiabetic and diabetic patients: a systematic overview Stroke 32 10 2001 2426 2432
13. J.S. Krinsley Association between hyperglycemia and increased hospital mortality in a heterogeneous population of critically ill patients Mayo Clin Proc 78 12 2003 1471 1478
14. E.V. Faustino, and M. Apkon Persistent hyperglycemia in critically ill children J Pediatr 146 1 2005 30 34
15. G. Van den Berghe, K. Schoonheydt, and P. Becx Insulin therapy protects the central and peripheral nervous system of intensive care patients Neurology 64 8 2005 1348 1353
16. J.S. Krinsley Effect of an intensive glucose management protocol on the mortality of critically ill adult patients Mayo Clin Proc 79 8 2004 992 1000
17. N.J. Grey, and G.A. Perdrizet Reduction of nosocomial infections in the surgical intensive-care unit by strict glycemic control Endocr Pract 10 Suppl 2 2004 46 52
18. M. Hill, and R. McCallum Altered transcriptional regulation of phosphoenolpyruvate carboxykinase in rats following endotoxin treatment J Clin Invest 88 3 1991 811 816
19. E.A. Flores, N. Istfan, and J.J. Pomposelli Effect of interleukin-1 and tumor necrosis factor/cachectin on glucose turnover in the rat Metabolism 39 7 1990 738 743
20. C.H. Lang, C. Dobrescu, and G.J. Bagby Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output Endocrinology 130 1 1992 43 52
21. Y. Sakurai, X.J. Zhang, and R.R. Wolfe TNF directly stimulates glucose uptake and leucine oxidation and inhibits FFA flux in conscious dogs Am J Physiol 270 5 Pt 1 1996 E864 E872
22. S. Khani, and J.A. Tayek Cortisol increases gluconeogenesis in humans: its role in the metabolic syndrome Clin Sci (Lond) 101 6 2001 739 747
23. M.J. Watt, K.F. Howlett, and M.A. Febbraio Adrenaline increases skeletal muscle glycogenolysis, pyruvate dehydrogenase activation and carbohydrate oxidation during moderate exercise in humans J Physiol 534 Pt 1 2001 269 278
24. E.A. Richter, N.B. Ruderman, and H. Gavras Muscle glycogenolysis during exercise: dual control by epinephrine and contractions Am J Physiol 242 1 1982 E25 E32
25. K.J. Rodnick, R.C. Piper, and J.W. Slot Interaction of insulin and exercise on glucose transport in muscle Diabetes Care 15 11 1992 1679 1689
26. R.R. Wolfe, M.J. Durkot, and J.R. Allsop Glucose metabolism in severely burned patients Metabolism 28 10 1979 1031 1039
27. R.R. Wolfe, D.N. Herndon, and F. Jahoor Effect of severe burn injury on substrate cycling by glucose and fatty acids N Engl J Med 317 7 1987 403 408
28. J.M. Stephens, G.J. Bagby, and P.H. Pekala Differential regulation of glucose transporter gene expression in adipose tissue or septic rats Biochem Biophys Res Commun 183 2 1992 417 422
29. A. Virkamaki, and H. Yki-Jarvinen Mechanisms of insulin resistance during acute endotoxemia Endocrinology 134 5 1994 2072 2078
30. K. Meszaros, C.H. Lang, and G.J. Bagby Contribution of different organs to increased glucose consumption after endotoxin administration J Biol Chem 262 23 1987 10965 10970
31. D. Mesotten, J.V. Swinnen, and F. Vanderhoydonc Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy J Clin Endocrinol Metab 89 1 2004 219 226
32. D. Mesotten, P.J. Delhanty, and F. Vanderhoydonc Regulation of insulin-like growth factor binding protein-1 during protracted critical illness J Clin Endocrinol Metab 87 12 2002 5516 5523
33. A. Klip, T. Tsakiridis, and A. Marette Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures FASEB J 8 1 1994 43 53
34. G. Van den Berghe How does blood glucose control with insulin save lives in intensive care? J Clin Invest 114 9 2004 1187 1195
35. P. Pekala, M. Marlow, and D. Heuvelman Regulation of hexose transport in aortic endothelial cells by vascular permeability factor and tumor necrosis factor-alpha, but not by insulin J Biol Chem 265 30 1990 18051 18054
36. A.R. Shikhman, D.C. Brinson, and J. Valbracht Cytokine regulation of facilitated glucose transport in human articular chondrocytes J Immunol 167 12 2001 7001 7008
37. L.A. Quinn, and W.D. McCumbee Regulation of glucose transport by angiotensin II and glucose in cultured vascular smooth muscle cells J Cell Physiol 177 1 1998 94 102
38. C. Clerici, and M.A. Matthay Hypoxia regulates gene expression of alveolar epithelial transport proteins J Appl Physiol 88 5 2000 1890 1896
39. R. Sanchez-Alvarez, A. Tabernero, and J.M. Medina Endothelin-1 stimulates the translocation and upregulation of both glucose transporter and hexokinase in astrocytes: relationship with gap junctional communication J Neurochem 89 3 2004 703 714
40. T.A. Tirone, and F.C. Brunicardi Overview of glucose regulation World J Surg 25 4 2001 461 467
41. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 6865 2001 813 820
42. D. Giugliano, A. Ceriello, and G. Paolisso Oxidative stress and diabetic vascular complications Diabetes Care 19 3 1996 257 267
43. I.C. West Radicals and oxidative stress in diabetes Diabet Med 17 3 2000 171 180
44. K.S. Aulak, T. Koeck, and J.W. Crabb Dynamics of protein nitration in cells and mitochondria Am J Physiol Heart Circ Physiol 286 1 2004 H30 H38
45. I. Vanhorebeek, R. De Vos, and D. Mesotten Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients Lancet 365 9453 2005 53 59
46. M.R. Taskinen Pathogenesis of dyslipidemia in type 2 diabetes Exp Clin Endocrinol Diabetes 109 Suppl 2 2001 S180 S188
47. S. Lanza-Jacoby, S.H. Wong, and A. Tabares Disturbances in the composition of plasma lipoproteins during gram-negative sepsis in the rat Biochim Biophys Acta 1124 3 1992 233 240
48. W. Khovidhunkit, R.A. Memon, and K.R. Feingold Infection and inflammation-induced proatherogenic changes of lipoproteins J Infect Dis 181 Suppl 3 2000 S462 S472
49. Y.A. Carpentier, and O. Scruel Changes in the concentration and composition of plasma lipoproteins during the acute phase response Curr Opin Clin Nutr Metab Care 5 2 2002 153 158
50. M.G. Jeschke, D. Klein, and D.N. Herndon Insulin treatment improves the systemic inflammatory reaction to severe trauma Ann Surg 239 4 2004 553 560
51. T.N. Tulenko, and A.E. Sumner The physiology of lipoproteins J Nucl Cardiol 9 6 2002 638 649
52. H.W. Harris, C. Grunfeld, and K.R. Feingold Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice J Clin Invest 86 3 1990 696 702
53. H.W. Harris, C. Grunfeld, and K.R. Feingold Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death J Clin Invest 91 3 1993 1028 1034
54. X.J. Zhang, D.L. Chinkes, and O. Irtun Anabolic action of insulin on skin wound protein is augmented by exogenous amino acids Am J Physiol Endocrinol Metab 282 6 2002 E1308 E1315
55. D.C. Gore, S.E. Wolf, and A.P. Sanford Extremity hyperinsulinemia stimulates muscle protein synthesis in severely injured patients Am J Physiol Endocrinol Metab 286 4 2004 E529 E534
56. M.S. Agus, P.J. Javid, and D.P. Ryan Intravenous insulin decreases protein breakdown in infants on extracorporeal membrane oxygenation J Pediatr Surg 39 6 2004 839 844
57. T.A. Hillier, D.A. Fryburg, and L.A. Jahn Extreme hyperinsulinemia unmasks insulin's effect to stimulate protein synthesis in the human forearm Am J Physiol 274 6 Pt 1 1998 E1067 E1074
58. F. Weekers, A.P. Giulietti, and M. Michalaki Metabolic, endocrine, and immune effects of stress hyperglycemia in a rabbit model of prolonged critical illness Endocrinology 144 12 2003 5329 5338
59. T.K. Hansen, S. Thiel, and P.J. Wouters Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels J Clin Endocrinol Metab 88 3 2003 1082 1088
60. M.G. Jeschke, D. Klein, and U. Bolder Insulin attenuates the systemic inflammatory response in endotoxemic rats Endocrinology 145 9 2004 4084 4093
61. D. Klein, T. Schubert, and R.E. Horch Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma Ann Surg 240 2 2004 340 349
62. V. Brix-Christensen, S.K. Andersen, and R. Andersen Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model Anesthesiology 100 4 2004 861 870
63. C.T. Black, P.J. Hennessey, and R.J. Andrassy Short-term hyperglycemia depresses immunity through nonenzymatic glycosylation of circulating immunoglobulin J Trauma 30 7 1990 830 832
64. C.P. Nielson, and D.A. Hindson Inhibition of polymorphonuclear leukocyte respiratory burst by elevated glucose concentrations in vitro Diabetes 38 8 1989 1031 1035
65. A. Perner, S.E. Nielsen, and J. Rask-Madsen High glucose impairs superoxide production from isolated blood neutrophils Intensive Care Med 29 4 2003 642 645
66. A.J. Rassias, C.A. Marrin, and J. Arruda Insulin infusion improves neutrophil function in diabetic cardiac surgery patients Anesth Analg 88 5 1999 1011 1016
67. E.J. Rayfield, M.J. Ault, and G.T. Keusch Infection and diabetes: the case for glucose control Am J Med 72 3 1982 439 450
68. M.E. Carr Diabetes mellitus: a hypercoagulable state J Diabetes Complications 15 1 2001 44 54
69. J. Calles-Escandon, E. Garcia-Rubi, and S. Mirza Type 2 diabetes: one disease, multiple cardiovascular risk factors Coron Artery Dis 10 1 1999 23 30
70. E. Williams, W.R. Timperley, and J.D. Ward Electron microscopical studies of vessels in diabetic peripheral neuropathy J Clin Pathol 33 5 1980 462 470
71. G.M. Patrassi, R. Vettor, and D. Padovan Contact phase of blood coagulation in diabetes mellitus Eur J Clin Invest 12 4 1982 307 311
72. F. Carmassi, M. Morale, and R. Puccetti Coagulation and fibrinolytic system impairment in insulin dependent diabetes mellitus Thromb Res 67 6 1992 643 654
73. A. Hughes, B.A. McVerry, and L. Wilkinson Diabetes, a hypercoagulable state? Hemostatic variables in newly diagnosed type 2 diabetic patients Acta Haematol 69 4 1983 254 259
74. L.J. Garcia Frade, C.H. De La, and I. Alava Diabetes mellitus as a hypercoagulable state: its relationship with fibrin fragments and vascular damage Thromb Res 47 5 1987 533 540
75. U.N. Das Insulin: an endogenous cardioprotector Curr Opin Crit Care 9 5 2003 375 383
76. L. Langouche, I. Vanhorebeek, and D. Vlasselaers Intensive insulin therapy protects the endothelium of critically ill patients J Clin Invest 115 8 2005 2277 2286
77. M.P. Siroen, P.A. van Leeuwen, and R.J. Nijveldt Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Crit Care Med 33 3 2005 504 510
78. S.J. Finney, C. Zekveld, and A. Elia Glucose control and mortality in critically ill patients JAMA 290 15 2003 2041 2047