The methylene chloride fraction of trichosanthis fructus induces apoptosis in U937 cells through the mitochondrial pathway

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 1, 2006, Pages 21-25

  Lee, Eun Ok ^a   Lee, Ju Ryoung ^a   Kim, Kwan Hyun ^a   Baek, Nam In ^b   Lee, Soo Jin ^c   Lee, Bog Hieu ^b   Cho, Kyung Dong ^b   Ahn, Kyoo Seok ^d   Kim, Sung Hoon ^a  

^a Graduate School of East West Medical Science   (South Korea)

^b Kyung Hee University   (South Korea)

^c Department of Computer and Electronic Physics   (South Korea)

^d Chung Ang University   (South Korea)

Author keywords

Apoptosis; Caspase; Mitochondrial pathway; Trichosanthis kirilowii; U937 cell

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DICHLOROMETHANE; LIPOCORTIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPIDIUM IODIDE; PROTEIN BAX; PROTEIN BCL 2; TRICHOSANTHES EXTRACT;

APOPTOSIS; ARTICLE; CELL STRAIN U937; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DRUG MECHANISM; ENZYME ACTIVATION; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IC 50; MITOCHONDRION; NICK END LABELING; PLANT SEED; PROTEIN SECRETION; TRICHOSANTHES; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CELL DIVISION; CELL PROLIFERATION; CHROMATOGRAPHY, THIN LAYER; CYTOCHROMES C; CYTOSOL; FLOW CYTOMETRY; HUMANS; IN SITU NICK-END LABELING; KOREA; METHYLENE CHLORIDE; MITOCHONDRIA; PLANT EXTRACTS; PLANTS; SOLVENTS; U937 CELLS;

EID: 29844443679     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.21     Document Type: Article

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