메뉴 건너뛰기




Volumn 96, Issue 12 SUPPL. 2, 2005, Pages 8-12

Erectile dysfunction: Pathophysiologic mechanisms pointing to underlying cardiovascular disease

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN RECEPTOR ANTAGONIST; HYDRALAZINE; ISOPRENALINE; NITRIC ACID DERIVATIVE; NITRIC OXIDE; PHENTOLAMINE; PHOSPHODIESTERASE V INHIBITOR; PROSTACYCLIN; PROSTACYCLIN DERIVATIVE; SILDENAFIL;

EID: 29544448705     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2005.07.004     Document Type: Article
Times cited : (48)

References (43)
  • 1
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • H.A. Feldman, I. Goldstein, D.G. Hatzichristou, R.J. Krane, J.B. McKinlay Impotence and its medical and psychosocial correlates results of the Massachusetts Male Aging Study J Urol 151 1994 54 61
    • (1994) J Urol , vol.151 , pp. 54-61
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3    Krane, R.J.4    McKinlay, J.B.5
  • 2
  • 3
    • 0034243414 scopus 로고    scopus 로고
    • Male sexual circuitry. Working Group for the Study of Central Mechanisms in Erectile Dysfunction
    • I. Goldstein Male sexual circuitry. Working Group for the Study of Central Mechanisms in Erectile Dysfunction Sci Am 283 2000 70 75
    • (2000) Sci Am , vol.283 , pp. 70-75
    • Goldstein, I.1
  • 4
    • 0028837352 scopus 로고
    • Physiology of penile erection
    • K.E. Andersson, G. Wagner Physiology of penile erection Physiol Rev 75 1995 191 236
    • (1995) Physiol Rev , vol.75 , pp. 191-236
    • Andersson, K.E.1    Wagner, G.2
  • 6
    • 0031818659 scopus 로고    scopus 로고
    • Endogenous neurotransmitters mediating penile erection
    • A.M. Naylor Endogenous neurotransmitters mediating penile erection Br J Urol 81 1998 424 431
    • (1998) Br J Urol , vol.81 , pp. 424-431
    • Naylor, A.M.1
  • 7
    • 0026353632 scopus 로고
    • Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission
    • J. Rajfer, W.J. Aronson, P.A. Bush, F.J. Dorey, L.J. Ignarro Nitric oxide as a mediator of relaxation of the corpus cavernosum in response to nonadrenergic, noncholinergic neurotransmission N Engl J Med 326 1992 90 94
    • (1992) N Engl J Med , vol.326 , pp. 90-94
    • Rajfer, J.1    Aronson, W.J.2    Bush, P.A.3    Dorey, F.J.4    Ignarro, L.J.5
  • 8
    • 0025733506 scopus 로고
    • A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle
    • N. Kim, K.M. Azadzoi, I. Goldstein, I. Saenz de Tejada A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle J Clin Invest 88 1991 112 118
    • (1991) J Clin Invest , vol.88 , pp. 112-118
    • Kim, N.1    Azadzoi, K.M.2    Goldstein, I.3    Saenz De Tejada, I.4
  • 10
    • 0028802726 scopus 로고
    • Cyclic nucleotide phosphodiesterases: Functional implications of multiple isoforms
    • J.A. Beavo Cyclic nucleotide phosphodiesterases functional implications of multiple isoforms Physiol Rev 75 1995 725 748
    • (1995) Physiol Rev , vol.75 , pp. 725-748
    • Beavo, J.A.1
  • 12
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • R.F. Furchgott, J.V. Zawadzki The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine Nature 288 1980 373 376
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 13
    • 0242286648 scopus 로고    scopus 로고
    • Testing endothelial vasomotor function: Nitric oxide, a multipotent molecule
    • P. Ganz, J.A. Vita Testing endothelial vasomotor function nitric oxide, a multipotent molecule Circulation 108 2003 2049 2053
    • (2003) Circulation , vol.108 , pp. 2049-2053
    • Ganz, P.1    Vita, J.A.2
  • 14
    • 0037153047 scopus 로고    scopus 로고
    • Endothelial function: From vascular biology to clinical applications
    • D. Behrendt, P. Ganz Endothelial function from vascular biology to clinical applications Am J Cardiol 90 2002 40L 48L
    • (2002) Am J Cardiol , vol.90
    • Behrendt, D.1    Ganz, P.2
  • 15
    • 0037031310 scopus 로고    scopus 로고
    • Endothelial function: A barometer for cardiovascular risk?
    • J.A. Vita, J.F. Keaney Jr Endothelial function a barometer for cardiovascular risk? Circulation 106 2002 640 642
    • (2002) Circulation , vol.106 , pp. 640-642
    • Vita, J.A.1    Keaney Jr., J.F.2
  • 16
    • 0023974729 scopus 로고
    • Relationship of penile brachial pressure index to myocardial infarction and cerebrovascular accidents in older men
    • J.E. Morley, S.G. Korenman, F.E. Kaiser, A.D. Mooradian, S.P. Viosca Relationship of penile brachial pressure index to myocardial infarction and cerebrovascular accidents in older men Am J Med 84 1988 445 448
    • (1988) Am J Med , vol.84 , pp. 445-448
    • Morley, J.E.1    Korenman, S.G.2    Kaiser, F.E.3    Mooradian, A.D.4    Viosca, S.P.5
  • 17
    • 0032775015 scopus 로고    scopus 로고
    • Erectile dysfunction and cardiovascular disease
    • G. Jackson Erectile dysfunction and cardiovascular disease Int J Clin Pract 53 1999 363 368
    • (1999) Int J Clin Pract , vol.53 , pp. 363-368
    • Jackson, G.1
  • 18
    • 0034564088 scopus 로고    scopus 로고
    • Importance of asking questions about erectile dysfunction
    • L.A. Levine, R.A. Kloner Importance of asking questions about erectile dysfunction Am J Cardiol 86 2000 1210 1213 A5
    • (2000) Am J Cardiol , vol.86 , pp. 1210-1213
    • Levine, L.A.1    Kloner, R.A.2
  • 19
    • 1042275866 scopus 로고    scopus 로고
    • Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease
    • D.R. Kaiser, K. Billups, C. Mason, R. Wetterling, J.L. Lundberg, A.J. Bank Impaired brachial artery endothelium-dependent and -independent vasodilation in men with erectile dysfunction and no other clinical cardiovascular disease J Am Coll Cardiol 43 2004 179 184
    • (2004) J Am Coll Cardiol , vol.43 , pp. 179-184
    • Kaiser, D.R.1    Billups, K.2    Mason, C.3    Wetterling, R.4    Lundberg, J.L.5    Bank, A.J.6
  • 21
    • 0035808310 scopus 로고    scopus 로고
    • L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin
    • R. Heller, A. Unbehaun, B. Schellenberg, B. Mayer, G. Werner-Felmayer, E.R. Werner L-ascorbic acid potentiates endothelial nitric oxide synthesis via a chemical stabilization of tetrahydrobiopterin J Biol Chem 276 2001 40 47
    • (2001) J Biol Chem , vol.276 , pp. 40-47
    • Heller, R.1    Unbehaun, A.2    Schellenberg, B.3    Mayer, B.4    Werner-Felmayer, G.5    Werner, E.R.6
  • 22
    • 0035154347 scopus 로고    scopus 로고
    • The effect of superoxide dismutase on nitric oxide-mediated and electrical field-stimulated diabetic rabbit cavernosal smooth muscle relaxation
    • M.A. Khan, C.S. Thompson, J.Y. Jeremy, F.H. Mumtaz, P. Mikhailidis, R.J. Morgan The effect of superoxide dismutase on nitric oxide-mediated and electrical field-stimulated diabetic rabbit cavernosal smooth muscle relaxation BJU Int 87 2001 98 103
    • (2001) BJU Int , vol.87 , pp. 98-103
    • Khan, M.A.1    Thompson, C.S.2    Jeremy, J.Y.3    Mumtaz, F.H.4    Mikhailidis, P.5    Morgan, R.J.6
  • 23
    • 0041885877 scopus 로고    scopus 로고
    • Involvement of superoxide radical in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbits
    • S.C. Kim, I.K. Kim, K.K. Seo, K.J. Baek, M.Y. Lee Involvement of superoxide radical in the impaired endothelium-dependent relaxation of cavernous smooth muscle in hypercholesterolemic rabbits Urol Res 25 1997 341 346
    • (1997) Urol Res , vol.25 , pp. 341-346
    • Kim, S.C.1    Kim, I.K.2    Seo, K.K.3    Baek, K.J.4    Lee, M.Y.5
  • 25
    • 0034027210 scopus 로고    scopus 로고
    • Impairment of corpus cavernosal smooth muscle relaxation by glycosylated human haemoglobin
    • J.J. Cartledge, I. Eardley, J.F. Morrison Impairment of corpus cavernosal smooth muscle relaxation by glycosylated human haemoglobin BJU Int 85 2000 735 741
    • (2000) BJU Int , vol.85 , pp. 735-741
    • Cartledge, J.J.1    Eardley, I.2    Morrison, J.F.3
  • 26
    • 0034816774 scopus 로고    scopus 로고
    • Increased expression of arginase II in human diabetic corpus cavernosum: In diabetic-associated erectile dysfunction
    • T.J. Bivalacqua, W.J. Hellstrom, P.J. Kadowitz, H.C. Champion Increased expression of arginase II in human diabetic corpus cavernosum in diabetic-associated erectile dysfunction Biochem Biophys Res Commun 283 2001 923 927
    • (2001) Biochem Biophys Res Commun , vol.283 , pp. 923-927
    • Bivalacqua, T.J.1    Hellstrom, W.J.2    Kadowitz, P.J.3    Champion, H.C.4
  • 27
    • 0032865326 scopus 로고    scopus 로고
    • Androgen-dependent nitric oxide release in rat penis correlates with levels of constitutive nitric oxide synthase isoenzymes
    • R. Marin, A. Escrig, P. Abreu, M. Mas Androgen-dependent nitric oxide release in rat penis correlates with levels of constitutive nitric oxide synthase isoenzymes Biol Reprod 61 1999 1012 1016
    • (1999) Biol Reprod , vol.61 , pp. 1012-1016
    • Marin, R.1    Escrig, A.2    Abreu, P.3    Mas, M.4
  • 28
    • 0034730812 scopus 로고    scopus 로고
    • Targeting Rho in cardiovascular disease
    • U. Laufs, J.K. Liao Targeting Rho in cardiovascular disease Circ Res 87 2000 526 528
    • (2000) Circ Res , vol.87 , pp. 526-528
    • Laufs, U.1    Liao, J.K.2
  • 29
    • 0036182417 scopus 로고    scopus 로고
    • Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases
    • H. Shimokawa Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases J Cardiovasc Pharmacol 39 2002 319 327
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 319-327
    • Shimokawa, H.1
  • 32
    • 0037421504 scopus 로고    scopus 로고
    • Clinical results with AGI-1067: A novel antioxidant vascular protectant
    • J.C. Tardif Clinical results with AGI-1067 a novel antioxidant vascular protectant Am J Cardiol 91 2003 41A 49A
    • (2003) Am J Cardiol , vol.91
    • Tardif, J.C.1
  • 33
    • 0142121508 scopus 로고    scopus 로고
    • Therapeutic potential of breakers of advanced glycation end product-protein crosslinks
    • S. Vasan, P. Foiles, H. Founds Therapeutic potential of breakers of advanced glycation end product-protein crosslinks Arch Biochem Biophys 419 2003 89 96
    • (2003) Arch Biochem Biophys , vol.419 , pp. 89-96
    • Vasan, S.1    Foiles, P.2    Founds, H.3
  • 34
    • 0036673903 scopus 로고    scopus 로고
    • Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes
    • C. Desouza, A. Parulkar, D. Lumpkin, D. Akers, V.A. Fonseca Acute and prolonged effects of sildenafil on brachial artery flow-mediated dilatation in type 2 diabetes Diabetes Care 25 2002 1336 1339
    • (2002) Diabetes Care , vol.25 , pp. 1336-1339
    • Desouza, C.1    Parulkar, A.2    Lumpkin, D.3    Akers, D.4    Fonseca, V.A.5
  • 37
    • 0033858827 scopus 로고    scopus 로고
    • Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure
    • S.D. Katz, K. Balidemaj, S. Homma, H. Wu, J. Wang, S. Maybaum Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure J Am Coll Cardiol 36 2000 845 851
    • (2000) J Am Coll Cardiol , vol.36 , pp. 845-851
    • Katz, S.D.1    Balidemaj, K.2    Homma, S.3    Wu, H.4    Wang, J.5    Maybaum, S.6
  • 38
    • 0037390759 scopus 로고    scopus 로고
    • Sildenafil for pulmonary arterial hypertension: Exciting, but protection required
    • S. Mehta Sildenafil for pulmonary arterial hypertension exciting, but protection required Chest 123 2003 989 992
    • (2003) Chest , vol.123 , pp. 989-992
    • Mehta, S.1
  • 41
    • 0037233411 scopus 로고    scopus 로고
    • The role of the NO axis and its therapeutic implications in pulmonary arterial hypertension
    • E.D. Michelakis The role of the NO axis and its therapeutic implications in pulmonary arterial hypertension Heart Fail Rev 8 2003 5 21
    • (2003) Heart Fail Rev , vol.8 , pp. 5-21
    • Michelakis, E.D.1
  • 42
    • 1842530387 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
    • B.K. Sastry, C. Narasimhan, N.K. Reddy, B.S. Raju Clinical efficacy of sildenafil in primary pulmonary hypertension a randomized, placebo-controlled, double-blind, crossover study J Am Coll Cardiol 43 2004 1149 1153
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1149-1153
    • Sastry, B.K.1    Narasimhan, C.2    Reddy, N.K.3    Raju, B.S.4
  • 43
    • 0242349756 scopus 로고    scopus 로고
    • Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension
    • E.D. Michelakis, W. Tymchak, M. Noga, L. Webster, X.C. Wu, D. Lien, S.H. Wang, D. Modry, S.L. Archer Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension Circulation 108 2003 2066 2069
    • (2003) Circulation , vol.108 , pp. 2066-2069
    • Michelakis, E.D.1    Tymchak, W.2    Noga, M.3    Webster, L.4    Wu, X.C.5    Lien, D.6    Wang, S.H.7    Modry, D.8    Archer, S.L.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.