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Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 3, 2006, Pages 727-730

A novel class of sodium/calcium exchanger inhibitors: Design, synthesis, and structure-activity relationships of 4-phenyl-3-(piperidin-4-yl)-3,4-dihydro- 2(1H)-quinazolinone derivatives

(4) Hasegawa, Hirohiko a Muraoka, Masami a Matsui, Kazuki a Kojima, Atsuyuki b

a DAINIPPON SUMITOMO PHARMA CO LTD (Japan)

b Sumika Technoservice Corporation (Japan)

Author keywords

4 Phenyl 3 (piperidin 4 yl) 3,4 dihydro 2(1H) quinazolinone derivatives; Inhibitor; Na+ Ca2+ exchanger; Sodium calcium exchanger

Indexed keywords

5 (N,N DIMETHYL)AMILORIDE; QUINAZOLINONE DERIVATIVE; SM 15811; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG; VALYLMETHIONYLARGINYLPHENYLALANINAMIDE;

ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; INHIBITION KINETICS; STRUCTURE ACTIVITY RELATION;

DRUG DESIGN; ENZYME INHIBITORS; INHIBITORY CONCENTRATION 50; PIPERIDINES; QUINAZOLINES; SODIUM-CALCIUM EXCHANGER; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 29544439676 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2005.10.012 Document Type: Article

Times cited : (14)

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- note
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