Endothelial adhesion of synchronized gastric tumor cells changes during cell cycle transit and correlates with the expression level of CD44 splice variants

World Journal of Gastroenterology

Volumn 11, Issue 40, 2005, Pages 6243-6248

  Oertl, Anton ^a   Castein, Jens ^a   Engl, Tobias ^a   Beecken, Wolf Dietrich ^a   Jonas, Dietger ^a   Melamed, Richard ^a   Blaheta, Roman A ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Adhesion; CD44; Cell cycle; Gastrointestinal tumors

Indexed keywords

APHIDICOLIN; CD44V ANTIGEN; CD44V4 ANTIGEN; CD44V5 ANTIGEN; CD44V7 ANTIGEN; HERMES ANTIGEN; HYALURONIC ACID; LYMPHOCYTE ANTIGEN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANTIGEN FUNCTION; ARTICLE; CELL ADHESION; CELL CULTURE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL INTERACTION; CELL LINE; CELL SYNCHRONIZATION; CORRELATION ANALYSIS; ENDOTHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; MONOLAYER CULTURE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STOMACH ADENOCARCINOMA; TUMOR CELL; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

EID: 29544431803     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v11.i40.6243     Document Type: Article

References (27)

1. Jothy S. CD44 and its partners in metastasis. Clin Exp Metastasis 2003; 20: 195-201
2. Sumiyoshi Y, Yamashita Y, Maekawa T, Sakai N, Shirakusa T, Kikuchi M. Expression of CD44, vascular endothelial growth factor, and proliferating cell nuclear antigen in severe venous invasional colorectal cancer and its relationship to liver metastasis. Surg Today 2000; 30: 323-327
3. Yue SQ, Yang YL, Dou KF, Li KZ. Expression of PCNA and CD44mRNA in colorectal cancer with venous invasion and its relationship to liver metastasis. World J Gastroenterol 2003; 9: 2863-2865
4. Jungling B, Menges M, Goebel R, Wittig BM, Weg-Remers S, Pistorius G, Schilling M, Bauer M, Konig J, Zeitz M, Stallmach A. Expression of CD44v6 has no prognostic value in patients with colorectal cancer. Z Gastroenterol 2002; 40: 229-233
5. Indinnimeo M, Cicchini C, Giarnieri E, Stazi A, Mingazzini PL, Stipa V. Evaluation of CD44 variant 6 expression and clinicopathological factors in pulmonary metastases from colon carcinoma. Oncol Rep 2003; 10: 1875-1877
6. Abbasi AM, Chester KA, Talbot IC, Macpherson AS, Boxer G, Forbes A, Malcolm AD, Begent RH. CD44 is associated with proliferation in normal and neoplastic human colorectal epithelial cells. Eur J Cancer 1993; 29: 1995-2002
7. Ioachim E, Goussia A, Agnantis NJ. Glycoprotein CD44 expression in colorectal neoplasms. An immuno-histochemical study including correlation with cathepsin D, extracellular matrix components, p53, Rb, bcl-2, c-erbB-2, EGFR and proliferation indices. Virchows Arch 1999; 434: 45-50
8. Furuta K, Zahurak M, Yang XL, Rosada C, Goodman SN, August JT, Hamilton SR. Relationship between CD44 expression and cell proliferation in epithelium and stroma of colorectal neoplasms. Am J Pathol 1996; 149: 1147-1155
9. Blaheta RA, Kronenberger B, Woitaschek D, Weber S, Scholz M, Schuldes H, Encke A, Markus BH. Development of an ultrasensitive in vitro assay to monitor growth of primary cell cultures with reduced mitotic activity. J Immunol Methods 1998; 211: 159-169
10. Miyake K, Underhill CB, Lesley J, Kincade PW. Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition. J Exp Med 1990; 172: 69-75
11. Tarin D, Bolodeoku J, Hatfill SJ, Sugino T, Woodman AC, Yoshida K. The clinical significance of malfunction of the CD44 locus in malignancy. J Neurooncol 1995; 26: 209-219
12. Tolg C, Hofmann M, Herrlich P, Ponta H. Splicing choice from 10 variant exons establishes CD44 variability. Nucleic Acids Res 1993; 21: 1225-1229
13. Leister I, Manegold S, Schuler P, Alves F, Becker H, Fuzesi L, Markus PM. Effect of laparotomy and CO(2) pneumoperitoneum on tumor growth of human colon carcinoma and expression pattern of tumor-associated proteins in the SCID mouse. Int J Colorectal Dis 2003; 18: 508-513
14. Mulder JW, Wielenga VJ, Polak MM, van den Berg FM, Adolf GR, Herrlich P, Pals ST, Offerhaus GJ. Expression of mutant p53 protein and CD44 variant proteins in colorectal tumorigenesis. Gut 1995; 36: 76-80
15. Mulder JW, Kruyt PM, Sewnath M, Seldenrijk CA, Weidema WF, Pals ST, Offerhaus GJ. Difference in expression of CD44 splice variants between proximal and distal adenocarcinoma of the large bowel. Br J Surg 1995; 82: 1468-1470
16. Heider KH, Dammrich J, Skroch-Angel P, Muller-Hermelink HK, Vollmers HP, Herrlich P, Ponta H. Differential expression of CD44 splice variants in intestinal- and diffuse-type human gastric carcinomas and normal gastric mucosa. Cancer Res 1993; 53: 4197-4203
17. Harn HJ, Ho LI, Chang JY, Wu CW, Jiang SY, Lee HS, Lee WH. Differential expression of human metastasis adhesion molecule CD44V in Chinese stomach carcinoma. Cancer 1995; 75: 1065-1071
18. Montgomery E, Abraham SC, Fisher C, Deasel MR, Amr SS, Sheikh SS, House M, Lilliemoe K, Choti M, Brock M, Ephron DT, Zahuruk M, Chadburn A. CD44 loss in gastric stromal tumors as a prognostic marker. Am J Surg Pathol 2004; 28: 168-177
19. Torbenson M, Dhir R, Nangia A, Becich MJ, Kapadia SB. Prostatic carcinoma with signet ring cells: a clinicopathologic and immunohistochemical analysis of 12 cases, with review of the literature. Mod Pathol 1998; 11: 552-559
20. Tempfer C, Losch A, Heinzl H, Hausler G, Hanzal E, Kolbl H, Breitenecker G, Kainz C. Prognostic value of immunohistochernically detected CD44 isoforms CD44v5, CD44v6 and CD44v7-8 in human breast cancer. Eur J Cancer 1996; 32: 2023-2025
21. Zada AA, Singh SM, Reddy VA, Elsasser A, Meisel A, Haferlach T, Tenen DG, Hiddemann W, Behre G. Downregulation of c-Jun expression and cell cycle regulatory molecules in acute myeloid leukemia cells upon CD44 ligation. Oncogene 2003; 22: 2296-2308
22. Oruetxebarria I, Venturini F, Kekarainen T, Houweling A, Zuijderduijn LM, Mohd-Sarip A, Vries RG, Hoeben RC, Verrijzer CP. P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells. J Biol Chem 2004; 279: 3807-3816
23. Righi L, Deaglio S, Pecchioni C, Gregorini A, Horenstein AL, Bussolati G, Sapino A, Malavasi F. Role of CD31/platelet endothelial cell adhesion molecule-1 expression in in vitro and in vivo growth and differentiation of human breast cancer cells. Am J Pathol 2003; 162: 1163-1174
24. Kurozumi K, Nakao K, Nishida T, Nakahara M, Ogino N, Tsujimoto M. Significance of biologic aggressiveness and proliferating activity in papillary thyroid carcinoma. World J Surg 1998; 22: 1237-1242
25. Jackson PA, Green MA, Pouli A, Hubbard R, Marks CG, Cook MG. Relation between stage, grade, proliferation, and expression of p53 and CD44 in adenomas and carcinomas of the colorectum. J Clin Pathol 1995; 48: 1098-1101
26. Vairo G, Soos TJ, Upton TM, Zalvide J, DeCaprio JA, Ewen ME, Koff A, Adams JM. Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation. Mol Cell Biol 2000; 20: 4745-4753
27. Kaul R, Mukherjee S, Ahmed F, Bhat MK, Chhipa R, Galande S, Chattopadhyay S. Direct interaction with and activation of p53 by SMAR1 retards cell-cycle progression at G2/M phase and delays tumor growth in mice. Int J Cancer 2003; 103: 606-615