Structure of the His44 → Ala single point mutant of the distal finger motif of HIV-1 nucleocapsid protein: A combined NMR, molecular dynamics simulation, and fluorescence study

Biochemistry

Volumn 43, Issue 24, 2004, Pages 7687-7697

  Stote, Roland H ^a   Kellenberger, Esther ^b,c   Muller, Hervé ^a   Bombarda, Elisa ^d   Roques, Bernard P ^c   Kieffer, Bruno ^b   Mély, Yves ^d  

^a UNIVERSITÉ LOUIS PASTEUR   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c CNRS   (France)

^d UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; CONFORMATIONS; DISEASES; IMMUNOLOGY; MOLECULAR DYNAMICS; MOLECULAR STRUCTURE; VIRUSES;

IMMUNODEFICIENCY;

MUTAGENESIS;

ALANINE; DNA; HISTIDINE; NUCLEOCAPSID PROTEIN; PEPTIDE; PROTEIN NCP7; UNCLASSIFIED DRUG; ZINC ION; CAPSID PROTEIN; GAG PROTEIN; NCP7 PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; FLUORESCENCE; HUMAN IMMUNODEFICIENCY VIRUS 1; METAL BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DNA BINDING; PROTEIN MOTIF; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; SIMULATION; VIRUS INFECTIVITY; VIRUS NUCLEOCAPSID; ZINC FINGER MOTIF; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; NUCLEAR MAGNETIC RESONANCE; SPECTROFLUOROMETRY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

ALANINE; AMINO ACID MOTIFS; CAPSID PROTEINS; GENE PRODUCTS, GAG; HISTIDINE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; POINT MUTATION; SPECTROMETRY, FLUORESCENCE; VIRAL PROTEINS;

EID: 2942739181     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi036137u     Document Type: Article

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