Probing the topography of HIV-1 nucleocapsid protein with the alkylating agent N-ethylmaleimide

Biochemistry

Volumn 37, Issue 51, 1998, Pages 17890-17897

  Chertova, Elena N ^a,b   Kane, Bradley P ^a   McGrath, Connor ^a   Johnson, Donald G ^a   Sowder II, Raymond C ^a   Arthur, Larry O ^a   Henderson, Louis E ^a  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CYSTEINE; N ETHYLMALEIMIDE; NUCLEOCAPSID PROTEIN; RECOMBINANT PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; DRUG DESIGN; DRUG TARGETING; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; REACTION ANALYSIS; VIRUS NUCLEOCAPSID; VIRUS REPLICATION;

ALKYLATING AGENTS; AMINO ACID SEQUENCE; CAPSID; CAPSID PROTEINS; CYSTEINE; ETHYLMALEIMIDE; FLUORESCENCE POLARIZATION; GENE PRODUCTS, GAG; HIV-1; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; SEQUENCE ANALYSIS; VIRAL PROTEINS; ZINC FINGERS;

EID: 0032559060     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980907y     Document Type: Article

References (24)

1. Henderson, L. E., Sowder, R., Copeland, T. D., Smythers, G., and Oroszlan, S. (1984) J. Virol. 52, 492-500.
2. Copeland, T. D., Morgan, M. A., and Oroszlan, S. (1984) Virology 133, 137-145.
3. Aldovini, A., and Young, R. A. (1990) J. Virol. 64, 1920-1926.
4. Dupraz, P., Oertle, S., Meric, C., Damay, P., and Spahr, P. F. (1990) J. Virol. 64, 4978-4987.
5. Gorelick, R. J., Henderson, L. E., Hanser, J. P., and Rein, A. (1988) Proc. Natl. Acad. Sci. U.S.A. 85, 8420-8424.
6. Gorelick, R. J., Nigida, S. M., Jr., Bess, J. W., Jr., Arthur, L. O., Henderson, L. E., and Rein, A. (1990) J. Virol. 64, 3207-3211.
7. Gorelick, R. J., Chabot, D. J., Rein, A., Henderson, L. E., and Arthur, L. O. (1993) J. Virol. 67, 4027-4036.
8. Schwartz, M. D., Fiore, D., and Panganiban, A. T. (1997) J. Virol. 71, 9295-9305.
9. Zhang, Y., and Barklis, E. (1995) J. Virol. 69, 5716-5722.
10. Gorelick, R. J., Chabot, D. J., Ott, D. E., Gagliardi, T. D., Rein, A., Henderson, L. E., and Arthur, L. O. (1996) J. Virol. 70, 2593-2597.
11. Gallay, P., Swingler, S., Song, J., Bushman, F., and Trono, D. (1995) Cell 83, 569-576.
12. Henderson, L. E., Rice, W. G., and Arthur, L. O. (1995) in U.S. Patent Application USSN 08/312, pp 331, U.S.A.
13. Rice, W. G., Schaeffer, C. A., Harten, B., Villinger, F., South, T. L., Summers, M. F., Henderson, L. E., Bess, J. W., Jr., Arthur, L. O., McDougal, J. S., Orloff, S. L., Mendeleyev, J., and Kun, E. (1993) Nature 361, 473-475.
14. Rice, W. G., Supko, J. G., Malspeis, L., Buckheit, R. W., Jr., Clanton, D., Bu, M., Graham, L., Schaeffer, C. A., Turpin, J. A., Domagala, J., Rocco, G., Bader, J. P., Halliday, S. M., Coren, L., Sowder, R. C., II, Arthur, L. O., and Henderson, L. E. (1995) Science 270, 1194-1197.
15. Wu, W., Henderson, L. E., Copeland, T. D., Gorelick, R. J., Bosche, W. J., Rein, A., and Levin, J. G. (1996) J. Virol. 70, 7132-7142.
16. Fisher, R. J., Rein, A., Fivash, M., Urbaneja, M. A., Casas-Finet, J. R., Medaglia, M., and Henderson, L. E. (1998) J. Virol. 72, 1902-1909.
17. Summers, M. F., South, T. L., Kim, B., and Hare, D. R. (1990) Biochemistry 29, 329-340.
18. Hathout, Y., Fabris, D., Han, M. S., Sowder, R. C., 2nd, Henderson, L. E., and Fenselau, C. (1996) Drug. Metab. Dispos. 24, 1395-1400.
19. Tummino, P. J., Scholten, J. D., Harvey, P. J., Holler, T. P., Maloney, L., Gogliotti, R., Domagala, J., and Hupe, D. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 969-973.
20. Summers, M. F., Henderson, L. E., Chance, M. R., Bess, J. W., Jr., South, T. L., Blake, P. R., Sagi, I., Perez-Alvarado, G., Sowder, R. C. I., Hare, D. R., and Arthur, L. O. (1992) Protein Sci. 1, 563-574.
21. Mely, Y., Jullian, N., Morellet, N., De Rocquigny, H., Dong, C. Z., Piemont, E., Roques, B. P., and Gerard, D. (1994) Biochemistry 33, 12085-12091.
22. Morellet, N., de Rocquigny, H., Mely, Y., Jullian, N., Demene, H., Ottmann, M., Gerard, D., Darlix, J. L., Fournie-Zaluski, M. C., and Roques, B. P. (1994) J. Mol. Biol. 235, 287-301.
23. Lee, B. L., De Guzman, R. N., Turner, B., Tjandra, N., Bax, A., and Summers, M. F. (1998) J. Mol. Biol. 279, 633-649.
24. De Guzman, R. N., Wu, Z. R., Stalling, C. C., Pappalardo, L., Borer, P. N., and Summers, M. F. (1998) Science 279, 384-388.