IGF-I gene transfer in thermally injured rats

Gene Therapy

Volumn 6, Issue 6, 1999, Pages 1015-1020

  Jeschke, M G ^a,b,d   Barrow, R E ^a,b   Hawkins, H K ^a,b   Yang, K ^c   Hayes, R L ^c   Lichtenbelt, B J ^a,b   Perez Polo, J R ^b   Herndon, D N ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d SHRINERS HOSPITALS FOR CHILDREN   (United States)

Author keywords

Growth factor; Insulin like growth factor I; Liposomes; Trauma; Wound healing

Indexed keywords

BETA GALACTOSIDASE; CHOLESTEROL; COMPLEMENTARY DNA; LIPOSOME; MUSCLE PROTEIN; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN; CYTOPLASM; ENCAPSULATION; GASTROCNEMIUS MUSCLE; GENE TRANSFER; GENETIC TRANSFECTION; LIVER; MALE; MUSCLE; MYOFIBROBLAST; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; SCALD; SERUM; SKIN; THERMAL INJURY; WOUND HEALING;

ANIMALS; BURNS; GENE THERAPY; INSULIN-LIKE GROWTH FACTOR I; LIPOSOMES; MALE; RATS; RATS, SPRAGUE-DAWLEY; WOUND HEALING;

ANIMALIA;

EID: 0033058945     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300923     Document Type: Article

References (28)

1. Firedmann T. Overcoming the obstacles to gene therapy. Sci Am 1997; 6: 96-101.
2. Feigner PL. Nonviral strategies for gene therapy. Sci Am 1997; 6: 102-106.
3. Feigner PL, Tsai YL, Sukhu L. Improved cationic lipid formulations for in vivo gene therapy. Ann NY Acad Sci 1995; 772: 126-139.
4. Felgner PL. Improvements in cationic liposomes for in vivo gene transfer. Hum Gene Ther 1996; 7: 1791-1793.
5. Bangham AD. Physical structure and behavior of lipids and lipid enzymes. Adv Lipid Res 1963; 1: 65-104.
6. Sharata HH, Katz KH. Liposomes. Int J Dermatol 1996; 35: 761-769.
7. Wheeler CJ, Felgner PL, Tsai YT. A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci USA 1996; 93: 11454-11459.
8. Pierre E, Herndon DN, Barrow RE. Growth hormone therapy in the treatment of burns. In: Torosian MH (ed). Growth Hormone in Critical Illness: Research and Clinical Studies. RG Landes Co: Texas, 1996, pp 105-116.
9. Meyer NA, Barrow RE, Herndon DN. Combined insulin-like growth factor-1 and growth hormone improves weight loss and wound healing in burned rats. J Trauma 1996; 31: 1008-1012.
10. Huang KF, Chung DH, Herndon DN. Insulin-like growth factor-1 (IGF-I) reduces gut atrophy and bacterial translocation after severe burn injury. Arch Surg 1993; 128: 47-54.
11. Strock LL, Singh H, Abdullah A. The effect of insulin-like growth factor-1 on postburn hypermetabolism. Surgery 1990; 108: 161-164.
12. Clemmons DR. Insulin-like growth factor-1 as an anabolic agent in catabolic states. Ann Intern Med 1994; 120: 596-597.
13. Lo HC, Hinton PH, Peterson CA, Ney DM. Simultaneous treatment with IGF-I and GH additively increases anabolism in parenterally fed rats. Am J Physiol 1995; 269: E368-E376.
14. Zaizen Y, Ford EG, Costin G. The effect of perioperative exogenous growth hormone on wound bursting strength in normal and malnourished rats. J Ped Surg 1990; 25: 70-74.
15. Guler HP, Zapf J, Scheiwiller E, Froesch ER. Recombinant human insulin-like growth factor-1 stimulates growth and has distinct effects on organ size in hypophysectomized rats. Proc Natl Acad Sci USA 1988; 85: 4889-4893.
16. Walker JL, Ginalska-Malinowska G, Romer TE. Effects of the infusion of insulin-like growth factor-1 in a child with growth hormone insensitivity syndrome. New Engl J Med 1991; 324: 1483-1488.
17. Martin P. Wound healing-aiming for perfect skin regeneration. Science 1997; 276: 75-81.
18. Pierre EJ, Perez-Polo JR, Mitchell AT, Herndon DN. Insulin-like growth factor-1 liposomal gene transfer and systemic growth hormone stimulate wound healing. J Burn Care Rehab 1997; 18: 287-291.
19. Jabri N et al. Adverse effects of recombinant human insulin-like growth factor-I in obese insulin-resistant type II diabetic patients. Diabetes 1994; 43: 369-374.
20. Bondy CA et al. Clinical uses of insulin-like growth factor-I. Ann Intern Med 1994; 120: 593-601.
21. Gore DC et al. Effect of exogenous growth hormone on whole-body and isolated-limb protein kinetics in burned patients. Arch Surg 1991; 126: 38-43.
22. Herndon DN, Barrow RE, Kunkel KR, Rutan RL. Effects of recombinant human growth hormone on donor-site healing in severely burned children. Ann Surg 1990; 212: 424-431.
23. Steenfos HH. Growth factors and wound healing. Scand J Plast Reconstr Hand Surg 1994; 28: 95-105.
24. Alexander MY, Akhurst RJ. Liposome-mediated gene transfer and expresion via the skin. Hum Mol Genet 1995; 4: 2279-2285.
25. Herndon DN, Barrow RE, Rutan, RL. A comparison of conservative versus early excision. Ann Surg 1989; 209: 547-553.
26. Rodriguez JL, Miller CG, Garner WL. Correlation of the local and systemic cytokine response with clinical outcome following thermal injury. J Trauma 1993; 34: 684-694.
27. Herndon DN, Wilmore DW, Mason AD Jr, Pruitt BA Jr. Development and analysis of a small animal model stimulating the human postburn hypermetabolic response. J Surg Res 1978; 25: 394-403.
28. Yang K, Perez-Polo JR, Faustinella G. In vitro studies of liposome-mediated gene transfection. In: Perez-Polo JR (ed). Paradigms of Neural Injury; Methods of Neuroscience. Academic Press, 1996, pp 290-297.