(1R,4S,5R)-3-fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: The fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases

Organic and Biomolecular Chemistry

Volumn 2, Issue 11, 2004, Pages 1592-1596

  Frederickson, Martyn ^a   Roszak, Aleksander W ^b   Coggins, John R ^c   Lapthorn, Adrian J ^b   Abell, Chris ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER CONCENTRATION; CATALYSIS; ENZYMES; FLUORINE COMPOUNDS; MOLECULAR STRUCTURE; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY;

FLASH COLUMN CHROMATOGRAPHY; ISOELECTRONIC STRUCTUE; REACTION INHIBITORS;

CARBOXYLIC ACIDS;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

3 DEHYDROQUINATE DEHYDRATASE; 3 FLUORO 1,4,5 TRIHYDROXY 2 CYCLOHEXENE 1 CARBOXYLIC ACID; 3-DEHYDROQUINATE DEHYDRATASE; 3-FLUORO-1,4,5-TRIHYDROXY-2-CYCLOHEXENE-1-CARBOXYLIC ACID; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; CYCLOHEXENE DERIVATIVE; ENZYME INHIBITOR; HYDROLYASE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; MYCOBACTERIUM TUBERCULOSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLOHEXANECARBOXYLIC ACIDS; CYCLOHEXENES; ENZYME INHIBITORS; HYDRO-LYASES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; MYCOBACTERIUM TUBERCULOSIS;

EID: 2942715211     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b404535a     Document Type: Article

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