Effects of glucocorticoids on infiltrating cells and epithelial cells of nasal polyps

Annals of Otology, Rhinology and Laryngology

Volumn 113, Issue 6, 2004, Pages 465-473

  Watanabe, Kazumasa ^a,b   Kanaizumi, Etsuko ^a,b   Shirasaki, Hideaki ^a,b   Himi, Tetsuo ^a,b  

^a Sapporo Medical University ^*

^b SAPPORO MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Eosinophil; Epithelial cell; Glucocorticoid; Granulocyte macrophage colony stimulating factor; T lymphocyte

Indexed keywords

AMPHOTERICIN B; CYTOKINE; DEXAMETHASONE; EPIDERMAL GROWTH FACTOR; FLUTICASONE PROPIONATE; GLUCOCORTICOID; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HYDROCORTISONE; HYPOPHYSIS EXTRACT; INSULIN; INTERLEUKIN 4; LIOTHYRONINE; PENICILLIN G; STREPTOMYCIN SULFATE; TRANSFERRIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; APOPTOSIS; ARTICLE; CELL CULTURE; CELL INFILTRATION; CLINICAL ARTICLE; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NICK END LABELING; NOSE MUCOSA; NOSE POLYP; POLYPECTOMY; PRIORITY JOURNAL; STEROID THERAPY; T LYMPHOCYTE;

EID: 2942695861     PISSN: 00034894     EISSN: None     Source Type: Journal    
DOI: 10.1177/000348940411300610     Document Type: Article

References (36)

1. Kanai N, Denburg J, Jordana M, Dolovich J. Nasal polyp inflammation. Effect of topical nasal steroid. Am J Respir Crit Care Med 1994;150:1094-100.
2. Elovic A, Wong DT, Weller PF, Matossian K, Galli SJ. Expression of transforming growth factors-alpha and beta 1 messenger RNA and product by eosinophils in nasal polyps. J Allergy Clin Immunol 1994;93:864-9.
3. Stoop AE, van der Heijden HA, Biewenga J, van der Baan S. Eosinophils in nasal polyps and nasal mucosa: an immunohistochemical study. J Allergy Clin Immunol 1993;91:616-22.
4. Simon HU, Yousefi S, Schranz C, Schapowal A, Bachert C, Blaser K. Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. J Immunol 1997;158:3902-8.
5. Tai PC, Sun L, Spry CJ. Effects of IL-5, granulocyte/macrophage colony-stimulating factor (GM-CSF) and IL-3 on the survival of human blood eosinophils in vitro. Clin Exp Immunol 1991;85:312-6.
6. Hamilos DL, Leung DY, Wood R, et al. Evidence for distinct cytokine expression in allergic versus nonallergic chronic sinusitis. J Allergy Clin Immunol 1995;96:537-44.
7. Pedersen CB, Mygind N, Sorensen H, Prytz S. Long-term treatment of nasal polyps with beclomethasone dipropionate aerosol. II. Clinical results. Acta Otolaryngol (Stockh) 1976;82:256-9.
8. Meagher LC, Cousin JM, Seckl JR, Haslett C. Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. J Immunol 1996;156:4422-8.
9. Lanza L, Scudeletti M, Puppo F, et al. Prednisone increases apoptosis in in vitro activated human peripheral blood T lymphocytes. Clin Exp Immunol 1996;103:482-90.
10. Cox G, Ohtoshi T, Vancheri C, et al. Promotion of eosinophil survival by human bronchial epithelial cells and its modulation by steroids. Am J Respir Cell Mol Biol 1991;4:525-31.
11. Xaubet A, Mullol J, Lopez E, et al. Comparison of the role of nasal polyp and normal nasal mucosal epithelial cells on in vitro eosinophil survival. Mediation by GM-CSF and inhibition by dexamethasone. Clin Exp Allergy 1994;24:307-17.
12. Shirasaki H, Kanaizumi E, Watanabe K, et al. Tumor necrosis factor increases MUC1 mRNA in cultured human nasal epithelial cells. Acta Otolaryngol (Stockh) 2003;123:524-31.
13. Fan GK, Itoh T, Imanaka M, Fujieda S, Takenaka H. Eosinophilic apoptosis in sinus mucosa: relationship to tissue eosinophilia and its resolution in allergic sinusitis. J Allergy Clin Immunol 2000;106:551-8.
14. Druilhe A, Wallaert B, Tsicopoulos A, et al. Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. Am J Respir Cell Mol Biol 1998;19:747-57.
15. Saunders MW, Wheatley AH, George SJ, Lai T, Birchall MA. Do corticosteroids induce apoptosis in nasal polyp inflammatory cells? In vivo and in vitro studies. Laryngoscope 1999;109:785-90.
16. Allen JS, Eisma R, Leonard G, Kreutzer D. Interleukin-3 interleukin-5, and granulocyte-macrophage colony-stimulating factor expression in nasal polyps. Am J Otolaryngol 1997;18:239-46.
17. Adachi T, Motojima S, Hirata A, et al. Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after stimulation with IL-5. J Allergy Clin Immunol 1996;98 (suppl):S207-S215.
18. Rudack C, Bachert C, Stoll W. Effect of prednisolone on cytokine synthesis in nasal polyps. J Interferon Cytokine Res 1999;19:1031-5.
19. Corrigan CJ, Hamid Q, North J, et al. Peripheral blood CD4 but not CD8 T-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy. Am J Respir Cell Mol Biol 1995;12:567-78.
20. Vignola AM, Chanez P, Chiappara G, et al. Evaluation of apoptosis of eosinophils, macrophages, and T lymphocytes in mucosal biopsy specimens of patients with asthma and chronic bronchitis. J Allergy Clin Immunol 1999;103:563-73.
21. Henriksson G, Norlander T, Forsgren J, Stierna P. Effects of topical budesonide treatment on glucocorticoid receptor mRNA down-regulation and cytokine patterns in nasal polyps. Am J Rhinol 2001;15:1-8.
22. Paliogianni F, Raptis A, Ahuja SS, Najjar SM, Boumpas DT. Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT. J Clin Invest 1993;91:1481-9.
23. Sanchez-Segura A, Brieva JA, Rodriguez C. T lymphocytes that infiltrate nasal polyps have a specialized phenotype and produce a mixed TH1/TH2 pattern of cytokines. J Allergy Clin Immunol 1998;102:953-60.
24. Shirasaki H, Watanabe K, Kanaizumi E, et al. Analysis of apoptotic cells in allergic and non-allergic nasal mucosa. Allergol Int 2001;50:311-7.
25. Bachert C, Gevaert P, Holtappels G, van Cauwenberge P. Mediators in nasal polyposis. Curr Allergy Asthma Rep 2002;2:481-7.
26. Tingsgaard PK, Larsen PL, Bock T, Lange Vejlsgaard G, Tos M. Expression of intercellular adhesion molecule-1 on the vascular endothelium in nasal polyps before, during and after topical glucocorticoid treatment. Acta Otolaryngol (Stockh) 1998;118:404-8.
27. Jahnsen FL, Haye R, Gran E, Brandtzaeg P, Johansen FE. Glucocorticosteroids inhibit mRNA expression for eotaxin, eotaxin-2, and monocyte-chemotactic protein-4 in human airway inflammation with eosinophilia. J Immunol 1999;163:1545-51.
28. Salvi S, Semper A, Blomberg A, et al. Interleukin-5 production by human airway epithelial cells. Am J Respir Cell Mol Biol 1999;20:984-91.
29. Reibman J, Talbot AT, Hsu Y, et al. Regulation of expression of granulocyte-macrophage colony-stimulating factor in human bronchial epithelial cells: roles of protein kinase C and mitogen-activated protein kinases. J Immunol 2000;165:1618-25.
30. Nakamura Y, Azuma M, Okano Y, et al. Upregulatory effects of interleukin-4 and interleukin-13 but not interleukin-10 on granulocyte/ macrophage colony-stimulating factor production by human bronchial epithelial cells. Am J Respir Cell Mol Biol 1996;15:680-7.
31. Finotto S, Ohno I, Marshall JS, et al. TNF-alpha production by eosinophils in upper airways inflammation (nasal polyposis). J Immunol 1994;153:2278-89.
32. Nonaka M, Nonaka R, Woolley K, et al. Distinct immunohistochemical localization of IL-4 in human inflamed airway tissues. IL-4 is localized to eosinophils in vivo and is released by peripheral blood eosinophils. J Immunol 1995;155:3234-44.
33. Jany B, Betz R, Schreck R. Activation of the transcription factor NF-kappa B in human tracheobronchial epithelial cells by inflammatory stimuli. Eur Respir J 1995;8:387-91.
34. Matsukura S, Stellato, C, Plitt JR, et al. Activation of eotaxin gene transcription by NF-kappa B and STAT6 in human airway epithelial cells. J Immunol 1999;163:6876-83.
35. Ray A, Zhang DH, Ray P. Antagonism of nuclear factor-kappa B functions by steroid hormone receptors. Biochem Soc Trans 1995;23:952-8.
36. Kim YK, Nakagawa N, Nakano K, Sulakvelidze I, Dolovich J, Denburg J. Stem cell factor in nasal polyposis and allergic rhinitis: increased expression by structural cells is suppressed by in vivo topical corticosteroids. J Allergy Clin Immunol 1997;100:389-99.