'Deaf, mute and whispering' silent synapses: Their role in synaptic plasticity

Journal of Physiology

Volumn 557, Issue 1, 2004, Pages 3-12

  Voronin, Leon L ^a   Cherubini, Enrico ^b  

^a INSTITUTE OF HIGHER NERVOUS ACTIVITY AND NEUROPHYSIOLOGY   (Russian Federation)

^b SISSA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; CALCIUM ION; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; CALCIUM;

ANIMAL CELL; ANIMAL TISSUE; BRAIN SLICE; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENDRITIC SPINE; DEPOLARIZATION; HYPOTHESIS; LONG TERM POTENTIATION; NERVE CELL PLASTICITY; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; PROBABILITY; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; REVIEW; SYNAPSE; TIME; CALCIUM CELL LEVEL; CELL FUNCTION; FACILITATION; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; NEUROTRANSMITTER RELEASE; PAIRED PULSE FACILITATION; POST TETANIC POTENTIATION; POSTSYNAPTIC TRANSMISSION; PRESYNAPTIC TRANSMISSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; SILENT SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; HUMANS; LONG-TERM POTENTIATION; NEURONAL PLASTICITY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSES; SYNAPTIC MEMBRANES;

EID: 2942679371     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.058966     Document Type: Review

References (42)

1. Antonova I, Arancio O, Trillat AC, Wang HG, Zablow L, Udo H, Kandel ER & Hawkins RD (2001). Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation. Science 294, 1547-1550.
2. Benke TA, Luthi A, Isaac IT & Collingridge GL (1998). Modulation of AMPA receptor unitary conductance by synaptic activity. Nature 393, 793-797.
3. Berretta N, Rossokhin AV, Cherubini E, Astrelin AV & Voronin LL (1999). Long-term synaptic changes induced by intracellular tetanization of CA3 pyramidal neurons in the hippocampal slices from juvenile rats. Neuroscience 93, 469-477.
4. Bliss TVP & Collingridge GL (1993). A synaptic model for memory: long-term potentiation in the hippocampus. Nature 361, 31-39.
5. Choi S, Klingauf J & Tsien RW (2000). Postfusional regulation of cleft glutamate concentration during LTP at 'silent synapses'. Nature Neurosci 3, 330-336.
6. Choi S, Klingauf J & Tsien RW (2003). Fusion pore modulation as a presynaptic mechanism contributing to expression of long-term potentiation. Philos Trans R Soc Lond B Biol Sci 358, 695-705.
7. Clark BA & Cull-Candy SG (2002). Activity-dependent recruitment of extrasynaptic NMDA receptor activation at an AMPA receptor-only synapse. J Neurosci 22, 4428-4436.
8. Cottrell JR, Dube GR, Egles C & Liu G (2000). Distribution, density, and clustering of functional glutamate receptors before and after synaptogenesis in hippocampal neurons. J Neurophysiol 84, 1573-1587.
9. Durand GM, Kovalchuk Y & Konnerth A (1996). Long-term potentiation and functional synapse induction in developing hippocampus. Nature 381, 71-75.
10. Emptage NJ, Reid CA, Fine A & Bliss TV (2003). Optical quantal analysis reveals a presynaptic component of LTP at hippocampal Schaffer associational synapses. Neuron 38, 797-804.
11. Esteban JA, Shi SH, Wilson C, Nuriya M, Huganir RL & Malinow R (2003). PKA phosphorylation of AMPA receptor subunits controls synaptic trafficking underlying plasticity. Nature Neurosci 6, 136-143.
12. Gasparini S, Saviane C, Voronin LL & Cherubini E (2000). Silent synapses in the developing hippocampus: Lack of functional AMPA receptors or low probability of glutamate release? Proc Natl Acad Sci U S A 97, 9741-9746.
13. Groc L, Gustafsson B & Hanse E (2002). Spontaneous unitary synaptic activity in CA1 pyramidal neurons during early postnatal development: constant contribution of AMPA and NMDA receptors. J Neurosci 22, 5552-5562.
14. Hayashi Y, Shi SH, Esteban JA, Piccini A, Poncer JC & Malinow R (2000). Driving AMPA receptors into synapses by LTP and CaMKII: requirement for GluR1 and PDZ domain interaction. Science 287, 2262-2267.
15. Isaac JT (2003). Postsynaptic silent synapses: evidence and mechanisms. Neuropharmacology 45, 450-460.
16. Isaac JT, Nicoll RA & Malenka RC (1995). Evidence for silent synapses: implications for the expression of LTP. Neuron 15, 427-434.
17. Kuhnt U & Voronin LL (1994). Interaction between paired-pulse facilitation and long-term potentiation in area CA1 of guinea-pig hippocampal slices: application of quantal analysis. Neuroscience 62, 391-397.
18. Kullmann DM (1994). Amplitude fluctuations of dual-componcnt EPSCs in hippocampal pyramidal cells: implications for long-term potentiation. Neuron 12, 1111-1120.
19. Kullmann DM (2003). Silent synapses: what are they telling us about long-term potentiation? Philos Trans R Soc Lond B Biol Sci 358, 727-733.
20. Kullmann DM, Erdeuli G & Asztely F (1996). LTP of AMPA and NMDA receptor-mediated signals: evidence for presynaptic expression and extrasynoptic glutamate spill-over. Neuron 17, 461-474.
21. Kullmann DM & Asztely F (1998). Extrasynaptic glutamate spillover in the hippocampus: evidence and implications. Trends Neurosci 21, 8-14.
22. Larkman AU & Jack JJ (1995). Synaptic plasticity: hippocampal LTP. Curr Opin Neurobiol 5, 324-334.
23. Liao D, Hessler NA & Malinow R (1995). Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature 375, 400-403.
24. Liao D, Scannevin RH & Huganir R (2001). Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors. J Neurosci 21, 6008-6017.
25. Maggi L, Le Magueresse C, Changeux J-P & Cherubini E (2003). Nicotine activates immature 'silent' connections in the developing hippocampus. Proc Natl Acad Sci U S A 100, 2059-2064.
26. Malinow R & Malenka RC (2002). AMPA receptor trafficking and synaptic plasticity. Ann Rev Neurosci 25, 103-126.
27. Manabe T & Nicoll RA (1994). Long-term potentiation: evidence against an increase in transmitter release probability in the CA1 region of the hippocampus. Science 265, 1888-1892.
28. Montgomery JM, Pavlidis P & Madison DV (2001). Pair recordings reveal all-silent synaptic connections and the postsynaptic expression of long-term potentiation. Neuron 29, 691-701.
29. Nicoll RA (2003). Expression mechanisms underlying long-term potentiation: a postsynaptic view. Philos Trans R Soc Lond B Biol Sci 358, 721-726.
30. Petralia RS, Esteban JA, Wang YX, Partridge JG, Zhao HM, Wenthold RJ & Malinow R (1999). Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses. Nature Neurosci 2, 31-36.
31. Piccini A & Malinow R (2002). Critical postsynaptic density 95/disc large/zonula occludens-I interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites. J Neurosci 22, 5387-5392.
32. Redman SV (1990). Quantal analysis of synaptic potentials in neurons of the central nervous system. Physiol Rev 70, 165-122.
33. Renger JJ, Egles C & Liu G (2001). A developmental switch in neurotransmitter flux enhances synaptic efficacy by affecting AMPA receptor activation. Neuron 29, 469-484.
34. Saviane C, Savtchenko LP, Raffaelli G, Voronin LL & Cherubini E (2002). Frequency-dependent shift from paired-pulse facilitation to paired-pulse depression at unitary CA3-CA3 synapses in the rat hippocampus. J Physiol 544, 469-476.
35. Schikorski T & Stevens CF (1997). Quantitative ultrastructural analysis of hippocampal excitatory synapses. J Neurosci 17, 5858-5867.
36. Schulz PE (1997). Long-term potentiation involves increases in the probability of neurotransmitter release. Proc Natl Acad Sci USA 94, 5888-5893.
37. Shi SH, Hayashi Y, Petralia RS, Zaman SH, Wenthold RJ, Svoboda K & Malinow R (1999). Rapid spine delivery and redistribution of AMPA receptors after synaptic NMDA receptor activation. Science 284, 1811-1816.
38. Voronin LL (1993). On the quantal analysis of hippocampal long-term potentiation and related phenomena of synaptic plasticity. Neuroscience 56, 275-304.
39. Voronin LL, Altinbaev RS, Bayazitov IT, Gasparini S, Kasyanov AV, Saviane C, Savtchenko L & Cherubini E (2004). Postsynaptic depolarisation enhances transmitter release and causes the appearance of responses at 'silent' synapses in rat hippocampus. Neuroscience, in the press.
40. Voronin LL & Cherubini E (2003). 'Presynaptic silence' may be golden. Neuropharmacology 45, 439-449.
41. Zakharenko SS, Zablow L & Siegelbaum SA (2001). Visualization of changes in presynaptic function during long-term synaptic plasticity. Nature Neurosci 4, 711-717.
42. Zhang LI & Poo MM (2001). Electrical activity and development of neural circuits. Nature Neurosci 4, 1207-1214.