Phospholipid synthesis is decreased in neuronal tissue in a mouse model of Sandhoff disease

Journal of Neurochemistry

Volumn 90, Issue 1, 2004, Pages 80-88

  Buccoliero, Rosaria ^a   Bodennec, Jacques ^a   Van Echten Deckert, Gerhild ^b   Sandhoff, Konrad ^b   Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Ganglioside; Lysosome; Phospholipid; Sandhoff; Sphingolipid; Tay Sachs

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE A; BETA N ACETYLHEXOSAMINIDASE B; CHOLINE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; GANGLIOSIDE GM2; PHOSPHATIDYLSERINE SYNTHASE; PHOSPHOLIPID; SERINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; GENE; GENE MUTATION; HEXB GENE; MOUSE; NERVE CELL; NEUROPATHOLOGY; NONHUMAN; PHOSPHOLIPID METABOLISM; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; SANDHOFF DISEASE; TAY SACHS DISEASE;

ANIMALS; BETA-N-ACETYLHEXOSAMINIDASE; BRAIN; CARBON RADIOISOTOPES; CDPDIACYLGLYCEROL-SERINE O-PHOSPHATIDYLTRANSFERASE; CELLS, CULTURED; CHOLINE; CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; LIVER; MICE; MICE, KNOCKOUT; NEURONS; ORGAN SPECIFICITY; PHOSPHOLIPIDS; SANDHOFF DISEASE; SERINE; SPLEEN; TRITIUM;

ANIMALIA;

EID: 2942648803     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02457.x     Document Type: Article

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