Prevention and treatment of leptospirosis

Expert Review of Anti-Infective Therapy

Volumn 2, Issue 2, 2004, Pages 293-298

  Edwards, Charles N ^a   Levett, Paul N ^b  

^a UNIVERSITY OF THE WEST INDIES   (Jamaica)

^b Saskatchewan Health   (Canada)

Author keywords

Ceftriaxone; Chemoprophylaxis; Doxycycline; Immunization; Penicillin; Waterborne; Zoonoses

Indexed keywords

AMPICILLIN; BACTERIAL VACCINE; CEFTRIAXONE; DESMOPRESSIN; DOXYCYCLINE; DOXYCYCLINE HYCLATE; ELECTROLYTE; INFUSION FLUID; NITRIC OXIDE; PARACETAMOL; PENICILLIN G;

ANIMAL HUSBANDRY; BACTERIAL TRANSMISSION; DRUG DOSE REGIMEN; DRUG EFFICACY; EPIDEMIC; FEVER; HEMOFILTRATION; HEMOPTYSIS; HUMAN; IMMUNIZATION; LEPTOSPIRA; LEPTOSPIROSIS; LUNG HEMORRHAGE; MYALGIA; PROTECTIVE CLOTHING; REVIEW; SOIL POLLUTION; WATER CONTAMINATION; ZOONOSIS;

EID: 2942566204     PISSN: 14787210     EISSN: None     Source Type: Journal    
DOI: 10.1586/14787210.2.2.293     Document Type: Review

References (44)

1. World Health Organization. Leptospirosis worldwide, 1999. Wkly Epidemiol. Rec. 74, 237-242 (1999).
2. Edwards CN. 'Leptospirosis'. In: Infectious Diseases. Cohen J, Powderly WG (Eds). Mosby, PA, USA (2004).
3. Johnson RC, Faine S. 'Leptospira'. In: Bergey's Manual of Systematic Bacteriology, Vol. 1. Krieg NR, Holt JG (Eds). Williams & Wilkins, BA, USA, 62-67 (1984).
4. Dikken H, Kmety E. 'Serological typing methods of leptospires'. In: Methods in Microbiology, Vol. 11. Bergan T, Norris JR (Eds). Academic Press, London, UK, 259-307 (1978).
5. Terpstra WJ. Typing leptospira from the perspective of a reference laboratory. Acta Leiden. 60, 79-87 (1992).
6. Yasuda PH, Steigerwalt AG, Sulzer KR, Kaufmann AF, Rogers F, Brenner DJ. Deoxyribonucleic acid relatedness between serogroups and serovars in the family Leptospiraceae with proposals for seven new Leptospira species. Int. J. Syst. Bacteriol. 37, 407-415 (1987).
7. Ramadass P, Jarvis BDW, Corner RJ, Penny D, Marshall RB. Genetic characterization of pathogenic Leptospira species by DNA hybridization. Int. J. Syst. Bacteriol. 42, 215-219 (1992).
8. Brenner DJ, Kaufmann AF, Sulzer KR, Steigerwalt AG, Rogers FC, Weyant RS. Further determination of DNA relatedness between serogroups and serovars in the family Leptospiraceae with a proposal for Leptospira alexanderi sp. nov. and four new Leptospira genomospecies. Int. J. Syst. Bacteriol. 49, 839-858 (1999).
9. Pérolat P, Chappel RJ, Adler B et al. Leptospira fainei sp. nov., isolated from pigs in Australia. Int. J. Syst. Bacteriol. 48, 851-858 (1998).
10. Levett PN. Leptospirosis. Clin. Microbiol. Rev. 14, 296-326 (2001).
11. Morgan J, Bornstein SL, Karpati AM et al. Outbreak of leptospirosis among Triathlon participants and community residents in Springfield, Illinois, 1998. Clin. Infect. Dis. 34, 1593-1599 (2002).
12. Sejvar J, Bancroft E, Winthrop K et al. Leptospirosis in 'Eco-Challenge' athletes, Malaysian Borneo, 2000. Emerg. Infect. Dis. 9, 702-707 (2003).
13. Sakamoto M, Sagara H, Koizumi N, Watanabe H. A case of leptospirosis infection in Borneo Island, Malaysia. Kansenshogaku Zasshi. 75, 1057-1061 (2001).
14. Evans M, Baranton G. Leptospirosis outbreak in Eco Challenge 2000 participants. Eurosurveil. Wkly (2000).
15. Douglin CP, Jordan C, Rock R, Hurley A, Levett PN. Risk factors for severe leptospirosis in the parish of St. Andrew, Barbados. Emerg. Infect. Dis. 3, 78-80 (1997).
16. Ko AI, Galvao Reis M, Ribeiro Dourado CM, Johnson WD, Riley LW, Salvador Leptospirosis Study Group. Urban epidemic of severe leptospirosis in Brazil. Lancet 354, 820-825 (1999).
17. Vinetz JM, Glass GE, Flexner CE, Mueller P, Kaslow DC. Sporadic urban leptospirosis. Ann. Int. Med. 125, 794-798 (1996).
18. Trevejo RT, Rigau-Perez JG, Ashford DA et al. Epidemic leptospirosis associated with pulmonary hemorrhage - Nicaragua, 1995. J. Infect. Dis. 178, 1457-1463 (1998).
19. Pan American Health Organization. Impact of Hurricane Mitch on Central America. Epidemiol. Bull. 19, 1-13 (1998).
20. World Health Organization. Leptospirosis, India. Report of the investigation of a post-cyclone outbreak in Orissa, November 1999. Wkly Epidemiol. Rec. 75, 217-223 (2000).
21. Sanders EJ, Rigau-Perez JG, Smits HL et al. Increase of leptospirosis in dengue-negative patients after a hurricane in Puerto Rico in 1996. Am. J. Trop. Med. Hyg. 61, 399-404 (1999).
22. Bharti AR, Nally JE, Ricaldi JN et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect. Dis. 3, 757-771 (2003).
23. Brown CA, Roberts AW, Miller MA et al. Leptospira interrogans serovar Grippotyphosa infection in dogs. J. Am. Vet. Med. Assoc. 209, 1265-1267 (1996).
24. Birnbaum N, Barr SC, Center SA, Schermerhorn T, Randolph JF, Simpson KW. Naturally acquired leptospirosis in 36 dogs: serological and clinicopathological features. J. Small Animal Prac. 39, 231-236 (1998).
25. Prescott JF, McEwen B, Taylor J, Woods JP, Abrams-Ogg A, Wilcock B. Resurgence of leptospirosis in dogs in Ontario: recent findings. Can. Vet. J. 43, 955-961 (2002).
26. Faine S, Adler B, Bolin C, Perolat P. Leptospira and leptospirosis, 2nd Edition. MedSci, Melbourne, Australia (1999).
27. Matthias MA, Levert PN. Leptospiral carriage by mice and mongooses on the island of Barbados. W. Indian Med. J. 51, 10-13 (2002).
28. Naiman BM, Alt D, Bolin CA, Zuerner R, Baldwin CL. Protective killed Leptospira borgpetersenii vaccine induces potent Th1 immunity comprising responses by CD4 and gammadelta T-lymphocytes. Infect. Immun. 69, 7550-7558 (2001).
29. Bolin CA, Alt DP. Use of a monovalent leptospiral vaccine to prevent renal colonization and urinary shedding in cattle exposed to Leptospira borgpetersenii serovar hardjo. Am. J. Vet. Res. 62, 995-1000 (2001).
30. Martínez Sánchez R, Pérez Sierra A, Baró Suárez M et al. Evaluación de la efectividad de una nueva vacuna contra la leptospirosis humana en grupos en riesgo. Pan. Am. J. Public Health 8, 385-392 (2000).
31. Takafuji ET, Kirkpatrick JW, Miller RN et al. An efficacy trial of doxycycline chemoprophylaxis against leptospirosis. N. Engl. J. Med. 310, 497-500 (1984).
32. Gonsalez CR, Casseb J, Monteiro FG et al. Use of doxycycline for leptospirosis after high-risk exposure in Sao Paulo, Brazil. Rev. Inst. Med. Trop. Sao Paulo. 41, 59-61 (1998).
33. Sehgal SC, Sugunan AP, Murhekar MV, Sharma S, Vijayachari P. Randomized controlled trial of doxycycline prophylaxis against leptospirosis in an endemic area. Int. J. Antimicrob. Agents. 13, 249-255 (2000).
34. McClain JBL, Ballou WR, Harrison SM, Steinweg DL. Doxycycline therapy for leptospirosis. Ann. Int. Med. 100, 696-698 (1984).
35. Edwards CN, Nicholson GD, Hassell TA, Everard COR, Callender J. Leptospirosis in Barbados: a clinical study. W. Indian Med. J. 39, 27-34 (1990).
36. Tse KC, Yip PS, Hui KM et al. Potential benefit of plasma exchange in treatment of severe icteric leptospirosis complicated by acute renal failure. Clin. Diagn. Lab. Immunol. 9, 482-484 (2002).
37. Borer A, Metz I, Gilad J et al. Massive pulmonary hemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration. J. Infect. 38, 42-45 (1999).
38. Pea L, Roda L, Boussaud V, Lonjon B. Desmopressin therapy for massive hemoptysis associated with severe leptospirosis. Am. J. Resp. Crit. Care Med. 167, 726-728 (2003).
39. Guidugli F, Castro AA, Atallah AN. Antibiotics for treating leptospirosis (Cochrane Review). In: Cochrane Library, Issue 3. Oxford: Update Software (2003).
40. Edwards CN, Nicholson GD, Hassell TA, Everard COR, Callender J. Penicillin therapy in icteric leptospirosis. Am. J. Trop. Med. Hyg. 39, 388-390 (1988).
41. Watt G, Padre LP, Tuazon ML et al. Placebo-controlled trial of intravenous penicillin for severe and late leptospirosis. Lancet 433-435 (1988).
42. Costa E, Lopes AA, Sacramento E et al. Penicillin at the late stage of leptospirosis: a randomized controlled trial. Rev. Inst. Med. Trop. Sao Paulo 45, 141-145 (2003).
43. Vientz J. A mountain out of a molehill: do we treat acute leptospirosis and if so, with what? Clin. Infect. Dis. 36, 1514-1515 (2003).
44. Panaphut T, Domrongkitchaiporn S, Vibhagool A, Thinkamrop B, Susaengrat W. Ceftriaxone compared with sodium penicillin G for treatment of severe leptospirosis. Clin. Infect. Dis. 36, 1507-1513 (2003).