Electron-transfer chemistry of Ru-linker-(heme)-modified myoglobin: Rapid intraprotein reduction of a photogenerated porphyrin cation radical

Inorganic Chemistry

Volumn 43, Issue 12, 2004, Pages 3593-3596

  Immoos, Chad E ^a   Di Bilio, Angel J ^b   Cohen, Michael S ^a   Van Der Veer, Wytze ^a   Gray, Harry B ^b   Farmer, Patrick J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOMYOGLOBIN; CATION; MYOGLOBIN; PORPHYRIN; RUTHENIUM COMPLEX;

ARTICLE; ELECTRON SPIN RESONANCE; ELECTRON TRANSPORT; OXIDATION REDUCTION REACTION; PHOTOCHEMISTRY; REACTION ANALYSIS; SYNTHESIS;

ANIMALS; APOPROTEINS; CATIONS; ELECTRON TRANSPORT; FREE RADICALS; HEME; HORSES; MOLECULAR STRUCTURE; MYOGLOBIN; OXIDATION-REDUCTION; PORPHYRINS; PROTEIN STRUCTURE, SECONDARY; RUTHENIUM;

EID: 2942547311     PISSN: 00201669     EISSN: None     Source Type: Journal    
DOI: 10.1021/ic049741h     Document Type: Article

References (36)

1. Ortiz de Montellano, P. R. Annu. Rev. Pharmacol. Toxicol. 1992, 32, 89-107.
2. Sono, M.; Roach, M. P.; Coulter, E. D.; Dawson, J. H. Chem. Rev. 1996, 96, 2841-2887.
3. Hiner, A. N. P.; Raven, E. L.; Thorneley, R. N. F.; Garcí a-Cánovas, F.; Rodríguez-López, J. N. J. Biol. Inorg. Chem. 2002, 7, 27-34.
4. Huyett, J. E.; Doan, P. E.; Gurbiel, R.; Houseman, A. L. P.; Sivaraja, M.; Goodin, D. B.; Hoffman, B. M. J. Am. Chem. Soc. 1995, 117, 9033-9041.
5. Stubbe, J.; van der Donk, W. A. Chem. Rev. 1998, 98, 705-762.
6. Pesavento, R. P.; Van Der Donk, W. A. Adv. Protein Chem. 2001, 58, 317-385.
7. Chouchane, S.; Girotto, S.; Yu, S. W.; Magliozzo, R. S. J. Biol. Chem. 2002, 277, 42633-42638.
8. Ivancich, A.; Jakopitsch, C.; Auer, M.; Un, S.; Obinger, C. J. Am. Chem. Soc. 2003, 125, 14093-14102.
9. Gibson, J. F.; Ingram, D. J. E.; Nicholls, P. Nature 1958, 181, 1398-1399.
10. He, B.; Sinclair, R.; Copeland, B. R.; Makino, R.; Powers, L. S.; Yamazaki, I. Biochemistry 1996, 35, 2413-2420.
11. Gunther, M. R.; Tschirret-Guth, R. A.; Lardinois, O. M.; Ortiz de Montellano, P. R. Chem. Res. Toxicol. 2003, 16, 652-660.
12. Svistunenko, D. A.; Dunne, J.; Fryer, M.; Nicholls, P.; Reeder, B. J.; Wilson, M. T.; Bigotti, M. G.; Cutruzzola, F.; Cooper, C. E. Biophys. J. 2002, 83, 2845-2855.
13. Hamachi, I.; Tsukiji, S.; Shinkai, S.; Oishi, S. J. Am. Chem. Soc. 1999, 121, 5500-5506.
14. Hamachi, I.; Takashima, H.; Hu, Y. Z.; Shinkai, S.; Oishi, S. Chem. Commun. 2000, 13, 1127-1128.
15. Tsuchida, E.; Nishide, H.; Sato, Y.; Kaneda, M. Bull. Chem. Soc. Jpn. 1982, 55, 1890-1895.
16. Martinis, S. A.; Sotiriou, C.; Chang, C. K.; Sligar, S. G. Biochemistry 1989, 28, 879-884.
17. Bjerrum, M. J.; Casimiro, D. R.; Chang, I.-J.; Di Bilio, A. J.; Gray, H. B.; Hill, M. G.; Langen, R.; Mines, G. A.; Skov, L. K.; Winkler, J. R.; Wuttke, D. S. J. Bioenerg. Biomembr. 1995, 27, 295-302.
18. Berglund, J.; Pascher, T.; Winkler, J. R.; Gray, H. B. J. Am. Chem. Soc. 1997, 119, 2464-2469.
19. Low, D. W.; Winkler, J. R.; Gray, H. B. J. Am. Chem. Soc. 1996, 118, 117-120.
20. 3+ (Hickman, D. L.; Nanthakumar, A.; Goff, H. M. J. Am. Chem. Soc. 1988, 110, 6384-6390).
21. . (∼530 nm) absorptions are totally masked by intense heme Soret and Q bands.
22. 2O binding.
23. Harriman, A. J. Phys. Chem. 1987, 91, 6102-6104.
24. Tommos, C.; Skalicky, J. J.; Pilloud, D. L.; Wand, A. J.; Dutton, P. L. Biochemistry 1999, 38, 9495-9507.
25. Defelippis, M. R.; Murthy, C. P.; Faraggi, M.; Klapper, M. H. Biochemistry 1989, 28, 4847-4853.
26. Farhangrazi, Z. S.; Sinclair, R.; Powers, L.; Yamzaki, I. Biochemistry 1995, 34, 14970.
27. Di Bilio, A. J.; Crane, B. R.; Wehbi, W. A.; Kiser, C. N.; Abu-Omar, M. M.; Carlos, R. M.; Richards, J. H.; Winkler, J. R.; Gray, H. B. J. Am. Chem. Soc. 2001, 123, 3181-3182.
28. Tew, D.; Ortiz de Montellano, P. R. J. Biol. Chem. 1988, 263, 17880-17886.
29. Harris, M. N.; Burchiel, S. W.; Winyard, P. G.; Engen, J. R.; Mobarak, C. D.; Timmins, G. S. Chem. Res. Toxicol. 2002, 15, 1589-1594.
30. Sahlin, M.; Cho, K. B.; Pötsch, S.; Lytton, S. D.; Huque, Y.; Gunther, M. R.; Sjöberg, B. M.; Mason, R. P.; Gräslund, A. J. Biol. Inorg. Chem. 2002, 7, 74-82.
31. . formation.
32. The decay of the peroxo radical within 40 s is in accord with the ∼7 s lifetime of peroxo radicals in Mb.30 All the radicals observed in photolysis experiments on RuC7Mb, with the exception of the species corresponding to the EPR spectrum in Figure 4B (which persists longer than 2 min), decay within 40 s.
33. Kelman, D. J.; Degray, J. A.; Mason, R. P. J. Biol. Chem. 1994, 269, 7458-7463.
34. . are unknown.
35. Miller, J. E.; Gradinaru, C.; Crane, B. R.; Di Bilio, A. J.; Wehbi, W. A.; Un, S.; Winkler, J. R.; Gray, H. B. J. Am. Chem. Soc. 2003, 125, 14220-14221.
36. Evans, S. V.; Brayer, G. D. J. Mol. Biol. 1990, 213, 885-897.