Chemosensitivity assay in mice prostate tumor: Preliminary report of flow cytometry, DNA fragmentation, ion ratiometric methods of anti-neoplastic drug monitoring

Cancer Cell International

Volumn 4, Issue , 2004, Pages

  Sharma, Rakesh ^a   Kline, Richard ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Apoptosis; DNA fragmentation; Flow cytometry; Ion ratiometric assay; MRI; Prostate tumor

Indexed keywords

ANTINEOPLASTIC AGENT; CALCIUM ION; CAMPTOTHECIN; DNA FRAGMENT; DOCETAXEL; ETOPOSIDE; FLUORESCENT DYE; IONOMYCIN; MONENSIN; PHOSPHORUS 31; PHOSPHORYLCHOLINE; SODIUM 23; SODIUM ION;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CANCER CELL CULTURE; CELL DEATH; CHEMICAL ANALYSIS; CHEMOSENSITIVITY; CONTROLLED STUDY; DNA DETERMINATION; DRUG MECHANISM; DRUG MONITORING; DRUG RESPONSE; FLOW CYTOMETRY; IN VIVO STUDY; MOUSE; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; SODIUM CELL LEVEL; TUMOR CELL;

EID: 2942513551     PISSN: 14752867     EISSN: None     Source Type: Journal    
DOI: 10.1186/1475-2867-4-3     Document Type: Article

References (14)

1. Evan G, Vousden K: Proliferation, cell cycle and apoptosis in cancer. Nature 2001, 411:342-348.
2. Lin XS, Denmeade SR, Cisek L, Isaacs JT: Mechanism and role of growth arrest in programmed (apoptotic) death of prostatic cancer cells induced by thapsigargin. Prostate 1997, 33(3):201-7.
3. Kay PA, Riehle DL, Cheville JC et al.: Comparison of quantitative histomorphometry and DNA ploidy in tissue sections of prostate carcinoma. Anal Quant Cytol Histol 2002, 24(1):7-14.
4. Maier S, Reich E, Martin R, Bachem M, Altug V, Hautmann RE, Gschwend JE: Tributyrin induces differentiation, growth arrest and apoptosis in androgen-sensitive and androgen-resistant human prostate cancer cell lines. Int J Cancer 2000, 88(2):245-51.
5. Kline R, Wu EX, Petrylak DP, Szabolcs M, Alderson PO, Weisfeldt ML, Canon PJ, Katz J: Rapid in vivo monitoring of chemotherapeutic response using weighted sodium magnetic resonance imaging. Clin Cancer Res 2000, 6(6):2146-2156.
6. Mastbergen SC, Duivenvoorden I, Versteegh RT et al.: Cell cycle arrest and clonogenic tumor cells killed by divergent chemotherapeutic drugs. Anticancer Res 2000, 20(3A):1833-38.
7. Rockwell P, O'Connor WJ, King K et al.: Cell-surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci USA 1997, 94(12):6523-28.
8. Kopper KL, Adorante JS: Regulation of intracellular calcium in N1E-115 neuroblastoma cells: the role of Na(+)/Ca(++) exchange. Am J Physiol cell Physiol 2002, 282(5):C1000-8.
9. Lee VM, Quinn PA, Jennings SC, Halligan AW: Altered Na+/H+ exchanger isoform 1 activity in immortalized lymphoblasts from women with pre-eclampsia: evidence for an intermediate phenotype. Clin Sci(Lond) 2002, 103(5):503-9.
10. Winter PM, Poptani H, Bansal N: Effects of chemotherapy by 1,3-bis(2-chloroethyl)-1-nitrosourea on single quantum- and triple quantum-filtered 23Na and 31P nuclear magnetic resonance of the subcutaneously implanted 9L glioma. Cancer Res 2001, 61(5):2002-7.
11. Faivre S, Chan D, Salinas R, Woynarowska B, Woynarowski JM: DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells. Biochem Pharmacol 2003, 66(2):225-37.
12. Li Y, Raffo AJ, Drew L, Mao Y, Tran A, Petrylak DP, Fine RL: Fasmediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143. Cancer Res 2003, 63(7):1527-33.
13. Drew L, Fine RL, Do TN, Douglas GP, Petrylak DP: The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells. Clin Cancer Res 2002, 8(12):3922-32.
14. Petrylak DP: Chemotherapy for advanced hormone refractory prostate cancer. Urology 1999, 54(6A Suppl):30-5. Review