Bifunctional gonadotropin-releasing hormone antagonist-progesterone analogs with increased efficacy and duration of action

Endocrinology

Volumn 147, Issue 1, 2006, Pages 571-579

  Ratcliffe, Karen E ^a,e   Fraser, Hamish M ^a   Sellar, Robin ^a   Rivier, Jean ^b   Millar, Robert P ^a,c,d  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c UNIVERSITY OF CAPE TOWN   (South Africa)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e Inveresk Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHLORAMPHENICOL ACETYLTRANSFERASE; DEOXYCORTICOSTERONE; GONADORELIN; GONADORELIN ANTAGONIST; GONADORELIN DERIVATIVE; HORMONE BINDING PROTEIN; INOSITOL PHOSPHATE; PROGESTERONE; PROGESTERONE DERIVATIVE; STEROID; TESTOSTERONE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN COS7; DNA RESPONSIVE ELEMENT; DRUG ACTIVITY; DRUG CONJUGATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG HYDROXYLATION; HORMONE ACTION; HORMONE INHIBITION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; MALE; MARMOSET; METABOLIC CLEARANCE RATE; NONHUMAN; PLASMA PROTEIN BINDING; PRIORITY JOURNAL; REPORTER GENE; TESTOSTERONE BLOOD LEVEL;

ANIMALS; BLOOD PROTEINS; CELL CULTURE TECHNIQUES; GONADOTROPIN-RELEASING HORMONE; HALF-LIFE; HUMANS; INOSITOL PHOSPHATES; MALE; PROGESTERONE; RABBITS; RECEPTORS, LHRH; TRANSFECTION;

EID: 29344469102     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2004-1481     Document Type: Article

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