Quantification of low levels of amorphous content in sucrose by hyperDSC

International Journal of Pharmaceutics

Volumn 307, Issue 2, 2006, Pages 150-155

  Lappalainen, Minna ^a   Pitkänen, Ilkka ^a   Harjunen, Päivi ^b  

^a UNIVERSITY OF JYVÄSKYLÄ   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Amorphous content; Glass transition; HyperDSC; Sucrose

Indexed keywords

CRYSTALLIN; SUCROSE;

ARTICLE; CONTENT ANALYSIS; CORRELATION ANALYSIS; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; GLASS TRANSITION TEMPERATURE; GRINDING; HEAT; LINEAR REGRESSION ANALYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REACTION TIME;

CALORIMETRY, DIFFERENTIAL SCANNING; CRYSTALLIZATION; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; SUCROSE; THERMODYNAMICS; TRANSITION TEMPERATURE;

EID: 29244470558     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2005.09.029     Document Type: Article

References (37)

1. T. Carstensen, and K. Van Scoik Amorphous-to-crystalline transformation of sucrose Pharm. Res. 7 1990 1278 1281
2. K.L. Christensen, G.P. Pedersen, and H.G. Kristensen Physical stability of redispersible dry emulsions containing amorphous sucrose Eur. J. Pharm. Biopharm. 53 2002 147 153
3. P. Claudy, M. Siniti, and J. El Hajri Thermodynamic study of the glass relaxation phenomena, DSC study of annealing maltitol glass J. Therm. Anal. Calorim. 68 2002 251 264
4. J. Font, J. Muntasell, and E. Cesari Solid state amorhization of organic crystals and thermodynamic properties of amorphized solids Mater. Res. Bulletin 32 1997 1691 1696
5. P. Gabbott, P. Clarke, T. Mann, P. Royall, and S. Shergill A high-sensitivity, high-speed DSC technique: measurement of amorphous lactose Am. Lab. 35 2003 17-18, 20, 22
6. D. Gao, and H. Rytting Use of solution calorimetry to determine the extent of crystallinity of drugs and excipients Int. J. Pharm. 151 1997 183 192
7. H. Gloria, and D. Sievert Changes in the physical state of sucrose during dark chocolate processing J. Agric. Food Chem. 49 2001 2433 2436
8. B.C. Hancock, S.L. Shamblin, and Z. Zografi Molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures Pharm. Res. 12 1995 799 806
9. M. Hurtta, and I. Pitkänen Quantification of low levels of amorphous content in maltitol Thermochim. Acta 419 2004 19 29
10. M. Hurtta, I. Pitkänen, and J. Knuutinen Melting behaviour of d-sucrose d-glucose and d-fructose Carbohydr. Res. 339 2004 2267 2273
11. J. Kerč, and S. Srčič Thermal analysis of glassy pharmaceuticals Thermochim. Acta 248 1995 81 95
12. C. McGregor, M.H. Saunders, G. Buckton, and R.D. Saklatvala The use of high-speed differential scanning calorimetry (Hyper-DSC™) to study the thermal properties of carbamazepine polymorphs Thermochim. Acta 417 2004 231 237
13. P.D. Orford, R. Paker, and S.G. Ring Aspects of the glass transition behaviour of mixtures of carbohydrates of low molecular weight Carbohydr. Res. 196 1990 11 18
14. Perkin-Elmer. Measurement of the Fictive Temperature of Polystyrene. Thermal Analysis Newsletter, Application Example PETAN-51.
15. T.F.J. Pijpers, V.B.F. Mathot, B. Goderis, R.L. Scherrenberg, and E.W. van der Vegte High-speed calorimetry for the study of the kinetics of (de)vitrification, crystallization, and melting of macromolecules Macromolecules 35 2002 3601 3613
16. A. Raemy, C. Kaabi, E. Ernst, and G. Vuataz Precise determination of low level sucrose amorphism by microcalorimetry J. Therm. Anal. 40 1993 437 444
17. Robinson, P., 2002. HyperDSC, High Speed DSC Technique. Abstract Book of ESTAC8, p. 101.
18. Y. Roos, and M. Karel Plasticizing effect of water on thermal behaviour and crystallization of amorphous food models J. Food Sci. 56 1991 38 43
19. Y. Roos Phase Transitions in Foods 1995 Academic Press Inc. San Diego
20. Y. Roos Melting and glass transitions of low molecular weight carbohydrates Carbohydr. Res. 238 1993 39 48
21. A. Saleki-Gerhardt, and G. Zografi Non-isothermal and isothermal crystallization of sucrose from the amorphous state Pharm. Res. 11 1994 1166 1173
22. A. Saleki-Gerhardt, C. Ahlneck, and G. Zografi Assessment of disorder in crystalline solids Int. J. Pharm. 101 1994 237 247
23. M. Saunders, K. Podluii, S. Shergill, G. Buckton, and P. Royall The potential of high speed DSC (Hyper-DSC) for the detection and quantification of small amounts of amorphous content in predominantly crystalline samples Int. J. Pharm. 274 2004 35 40
24. S.L. Shamblin, E.Y. Huang, and G. Zografi The effects of co-lyophilized polymeric additives on the glass transition temperature and crystallization of amorphous sucrose J. Therm. Anal. 47 1996 1567 1579
25. S.L. Shamblin, and G. Zografi Enthalpy relaxation in binary amorphous mixtures containing sucrose Pharm. Res. 15 1998 1828 1834
26. S.L. Shamblin, and G. Zografi The effects of absorbed water on the properties of amorphous mixtures containing sucrose Pharm. Res. 16 1999 1119 1124
27. S.L. Shamblin, X. Tang, L. Chang, B. Hancock, and M.J. Pikal Characterization of the time scales of molecular motion in pharmaceutically important glasses J. Phys. Chem. B 103 1999 4113 4121
28. L. Slade, and H. Levine Beyond water activity: recent advances based on an alternative approach to the assessment of food quality and safety Crit. Rev. Food Sci. Nutr. 30 1991 115 360
29. I. Tsukushi, O. Yamamuro, and T. Matsuo Amorphization of organic compounds by ball milling Solid State Commun. 94 1995 1013 1018
30. I. Tsukushi, O. Yamamuro, and T. Matsuo Structural relaxations and thermodynamic properties of molecular amorphous solids by mechanical milling Progr. Theor. Phys. Suppl. 126 1997 89 92
31. R. Urbani, F. Sussich, S. Prejac, and A. Cesàro Enthalpy relaxation and glass transition behaviour of sucrose by static and dynamic DSC Thermochim. Acta 304/305 1997 359 367
32. I. Vanhal, and G. Blond Impact of melting conditions of sucrose on its glass transition temperature J. Agric. Food Chem. 47 1999 4285 4290
33. B. Wunderlich Thermal Analysis 1990 Academic Press Inc. San Diego
34. R. Wungtanagorn, and S.J. Schmidt Phenomenological study of enthalpy relaxation of amorphous glucose, fructose, and their mixture Thermochim. Acta 369 2001 95 116
35. O. Yamamuro, I. Tsukushi, and T. Matsuo Solid state amorphization of organic molecular crystals using a vibrating mill Mol. Cryst. Liq. Cryst. 227 1996 205 214
36. L. Yu Amorphous pharmaceutical solids: preparation, characterization and stabilization Adv. Drug. Deliv. Rev. 48 2001 27 42
37. X.M. Zeng, G.P. Martin, and C. Marriot Effects of molecular weight of polyvinylpyrrolidone on the glass transition and crystallization of co-lyophilized sucrose Int. J. Pharm. 218 2001 63 73