3-O-acetyl-11-keto-boswellic acid decreases basal intracellular Ca 2+ levels and inhibits agonist-induced Ca2+ mobilization and mitogen-activated protein kinase activation in human monocytic cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 316, Issue 1, 2006, Pages 224-232

  Poeckel, Daniel ^a   Tausch, Lars ^a   George, Sven ^a   Jauch, Johann ^b   Werz, Oliver ^c  

^a GOETHE UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2,4,6 TRIMETHYL N (META 3 TRIFLUOROMETHYLPHENYL)BENZENESULFONAMIDE; 3 O ACETYL 11 KETO BOSWELLIC ACID; BENZENESULFONAMIDE DERIVATIVE; CALCIUM ION; CATION CHANNEL; ENZYME ACTIVATOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; TERPENOID DERIVATIVE; THAPSIGARGIN; THROMBOCYTE ACTIVATING FACTOR; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CELL ACTIVATION; CELL ISOLATION; CELL STIMULATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; EVOKED RESPONSE; HUMAN; HUMAN CELL; MONOCYTE; NEUTROPHIL; PRIORITY JOURNAL;

ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CALCIUM; CALCIUM CHANNEL AGONISTS; CELL LINE; CELL MEMBRANE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INOSINE TRIPHOSPHATE; MITOGEN-ACTIVATED PROTEIN KINASES; MONOCYTES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLATELET ACTIVATING FACTOR; TRITERPENES;

EID: 29244468511     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.089466     Document Type: Article

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