HPLC-UV method development and validation for 16-dehydropregnenolone, a novel oral hypolipidaemic agent, in rat biological matrices for application to pharmacokinetic studies

Journal of Pharmaceutical and Biomedical Analysis

Volumn 33, Issue 4, 2003, Pages 755-764

  Singh, S K ^a   Mehrotra, Nitin ^a   Sabarinath, S ^a   Gupta, R C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Biomatrix; Dehydropregnenolonehypolipidaemic agents; Pharmacokinetics; Reversed phase chromatography

Indexed keywords

3 BETA HYDROXY 5,16 PREGNADIEN 20 ONE; ANTILIPEMIC AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG STORAGE; DRUG STRUCTURE; FECES ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0242457511     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(03)00308-X     Document Type: Article

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