Synthesis, conformational and pharmacological studies of glycosylated chimeric peptides of Met-enkephalin and FMRFa

Brain Research Bulletin

Volumn 68, Issue 5, 2006, Pages 329-334

  Masand, Gita ^a   Hanif, Kashif ^a   Sen, Somdutta ^a   Ahsan, Aarif ^a   Maiti, Souvik ^a   Pasha, Santosh ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

Bioavailability; Chimeric peptides; FMRFa; Glycosylated peptides; Met enkephalin

Indexed keywords

5 SERYLTYROSYLGLYCYLGLYCYLPHENYLALANYLMETHIONYLLYSYLLYSYLLYSYLPHENYLALANYL METHIONYLARGINYLPHENYLALANINAMIDE; GLUCOSE; GLUCOSE TRANSPORTER 1; METENKEPHALIN DERIVATIVE; O GALACTOSE 5 SERYLTYROSYLGLYCYLGLYCYLPHENYLALANYLMETHIONYLLYSYLLYSYLLYSYLPHENYLALANYL METHIONYLARGINYLPHENYLALANINAMIDE; O GLUTAMYL 5 SERYLTYROSYLGLYCYLGLYCYLPHENYLALANYLMETHIONYLLYSYLLYSYLLYSYLPHENYLALANYL METHIONYLARGINYLPHENYLALANINAMIDE; PEPTIDE; TYROSYLGLYCYLGLYCYLPHENYLALANYLMETHIONYLLYSYLLYSYLLYSYLPHENYLALANYL METHIONYLARGINYLPHENYLALAMIDE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; CHIMERA; CIRCULAR DICHROISM; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG CONFORMATION; DRUG EFFICACY; DRUG PENETRATION; DRUG STRUCTURE; DRUG SYNTHESIS; GLUCOSE TRANSPORT; GLYCOSYLATION; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS; STRUCTURE ANALYSIS; TAIL FLICK TEST;

ANIMALS; BLOOD-BRAIN BARRIER; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG INTERACTIONS; ENKEPHALIN, METHIONINE; FMRFAMIDE; GLYCOPEPTIDES; GLYCOSYLATION; MASS SPECTROMETRY; MICE; OLIGOPEPTIDES; PAIN; PAIN MEASUREMENT; PROTEIN CONFORMATION; REACTION TIME; TIME FACTORS;

EID: 29244460633     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2005.09.009     Document Type: Article

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