A polymorphism in the endothelin-A receptor gene is linked to baroreflex sensitivity

Journal of Hypertension

Volumn 23, Issue 11, 2005, Pages 2019-2026

  Ormezzano, Olivier ^a,f   Poirier, Odette ^c   Mallion, Jean Michel ^a   Nicaud, Viviane ^c   Amar, Jacques ^d   Chamontin, Bernard ^d   Mounier Véhier, Claire ^e   François, Patrice ^b   Cambien, François ^c   Baguet, Jean Philippe ^a  

^a Service de Cardiologie et Hypertension Artérielle   (France)

^b HÔPITAL MICHALLON   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d CHU PURPAN   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Baroreflex; Endothelin; Genetic; Human; Hypertension

Indexed keywords

ALDOSTERONE SYNTHASE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSINOGEN; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CLINICAL FEATURE; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; FEMALE; GENETIC ANALYSIS; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RECEPTOR GENE; SYSTOLIC BLOOD PRESSURE;

EID: 29244446240     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.hjh.0000184748.49189.36     Document Type: Article

References (48)

1. Mancia G, Parati G, Pomidossi G, Casadei R, Ri Rienzo M, Zanchetti A. Arterial baroreflexes and blood pressure and heart rate variabilities in humans. Hypertension 1986; 8:147-153.
2. Sasaki S, Yoneda Y, Fujita H, Uchida A, Takenaka K, Takesako T, et al. Association of blood pressure variability with induction of atherosclerosis in cholesterol-fed rats. Am J Hypertens 1994; 7:453-459.
3. Palatini P, Julius S. Heart rate and the cardiovascular risk. J Hypertens 1997; 15:3-17.
4. Kardos A, Watterich G, Menezes RD, Csanády M, Casadei B, Rudas L. Determinants of spontaneous baroreflex sensitivity in a healthy working population. Hypertension 2001; 37:911-916.
5. Iellamo F, Legramante JM, Pigozzi F, Spataro A, Norbiato G, Lucini D, Pagani M. Conversion from vagal to sympathetic predominance with strenuous training in high-performance world class athletes. Circulation 2002; 105:2719-2724.
6. Weinstock M, Weksler-Zangen S, Schorer-Apelbaum D. Genetic factors involved in the determination of baroreceptor heart-rate sensitivity. J Hypertens 1986; 4:s290-s292.
7. Tank J, Jordan J, Diedrich A, Stoffels M, Franke G, Faulhaber HD, et al. Genetic influences on baroreflex function in normal twins. Hypertension 2001; 37:907-910.
8. Pinna GD, La Rovere MT, Maestri R, Mortara A, Bigger JT, Schwartz PJ. Comparison between invasive and non-invasive measurements of baroreflex sensitivity; implications for studies on risk stratification after a myocardial infarction. Eur Heart J 2000; 21:1522-1529.
9. La Rovere MT, Pinna GD, Hohnloser SH, Marcus FI, Mortara A, Nohara R, et al., and the ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Baroreflex sensitivity and heart rate variability in the identification of patients at risk for life-threatening arrhythmias: implications for clinical trials. Circulation 2001; 103:2072-2077.
10. Mortara A, La Rovere MT, Pinna GD, Parziale P, Maestri R, Capomolla S, et al. Depressed arterial baroreflex sensitivity and not reduced heart rate variability identifies patients with chronic heart failure and nonsustained ventricular tachycardia: the effect of high ventricular filling pressure. Am Heart J 1997; 134:879-888.
11. La Rovere MT, Bigger JT Jr, Marcus FI, Mortara A, Schwartz PJ. Baroreflex sensitivity and heart-rate variability in prediction of total cardiac mortality after myocardial infarction. ATRAMI (Autonomic Tone and Reflexes After Myocardial Infarction) Investigators. Lancet 1998; 351:478-484.
12. Osterziel KJ, Hanlein D, Willenbrock R, Eichhorn C, Luft F, Dietz R. Baroreflex sensitivity and cardiovascular mortality in patients with mild to moderate heart failure. Br Heart J 1995; 73:517-522.
13. Ylitalo A, Airaksinen KE, Hautanen A, Kupari M, Carson M, Virolainen J, et al. Baroreflex sensitivity and variants of the renin angiotensin system genes. J Am Coll Cardiol 2000; 35:194-200.
14. Gollasch M, Tank J, Luft FC, Jordan J, Maass P, Krasko C, et al. The BK channel beta1 subunit gene is associated with human baroreflex and blood pressure regulation. J Hypertens 2002; 20:927-933.
15. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, et al., and the National High Blood Pressure Education Program Coordinating Committee. Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 2003; 42:1206-1252.
16. Benetos A, Gautier S, Ricard S, Topouchian J, Asmar R, Poirier O, et al. Influence of angiotensin-converting enzyme and angiotensin II type 1 receptor gene polymorphisms on aortic stiffness in normotensive and hypertensive patients. Circulation 1996; 94:698-703.
17. Imholz BPM, Wieling W, Langewouters GJ, Van Montfrans GA. Continuous finger arterial pressure: utility in the cardiovascular laboratory. Clin Auton Res 1991; 1:43-53.
18. Herpin D, Ragot S. Mid- and long-term reproducibility of noninvasive measurements of spontaneous arterial baroreflex sensitivity in healthy volunteers. Am J Hypertens 1997; 10:790-797.
19. Parati G, Di Rienzo M, Bertinieri G, Pomidossi G, Casadei R, Groppelli A, et al. Evaluation of the baroreceptor-heart rate reflex by 24-hour intra-arterial blood pressure monitoring in humans. Hypertension 1988; 12:214-222.
20. Di Rienzo M, Parati G, Castiglioni P, Tordi R, Mancia G, Pedotti A. Baroreflex effectiveness index: an additional measure of baroreflex control of heart rate in daily life. Am J Physiol Regul Integr Comp Physiol 2001; 280:R744-R751.
21. Pitzalis M, Parati G, Massari F, Guida P, Di Rienzo M, Rizzon B, et al. Enhanced reflex response to baroreceptor deactivation in subjects with tilt-induced syncope. J Am Coll Cardiol 2003; 41:1167-1173.
22. Tsuchiyama Y, Kasamatsu K, Hano T, Nishio I. Related articles, links acute effect of endothelin AB antagonist on sympathetic outflow in conscious rats with heart failure. Circ J 2002; 66:841-845.
23. Itoh S, van den Buuse M. Sensitization of baroreceptor reflex by central endothelin in conscious rats. Am J Physiol 1991; 260:H1106-H1112.
24. Van den Buuse M, Itoh S. Central effects of endothelin on baroreflex of spontaneously hypertensive rats. J Hypertens 1993; 11:379-387.
25. Dai SM, Shan ZZ, Miao CY, Yin M, Su DF. Hemodynamic responses to endothelin-1 and endothelin antagonists microinjected into the nucleus tractus solitarius in rats. J Cardiovasc Pharmacol 1997; 30:475-480.
26. Mosqueda-Garcia R, Appalsamy M, Fernandez-Violante R, Hamakubo T. Modulatory effects of endothelin on baroreflex activation in the nucleus of the solitary tract. Eur J Pharmacol 1998; 351:203-207.
27. Schiffrin EL, Thibault G. Plasma endothelin in human essential hypertension. Am J Hypertens 1991; 4:303-308.
28. Lemne CE, Lundeberg T, Theodorsson E, de Faire U. Increased basal concentrations of plasma endothelin in borderline hypertension. J Hypertens 1994; 12:1069-1074.
29. Schiffrin EL, Deng LY, Sventek P, Day R. Enhanced expression of endothelin-1 gene in resistance arteries in severe human essential hypertension. J Hypertens 1997; 15:57-63.
30. Hasegawa K, Fujiwara H, Doyama K, Inada T, Ohtani S, Fujiwara T, et al. Endothelin-1-selective receptor in the arterial intima of patients with hypertension. Hypertension 1994; 23:288-293.
31. Krum H, Viskoper RJ, Lacourciere Y, Budde M, Charlon V. The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators. N Engl J Med 1998; 338:784-790.
32. Nicaud V, Poirier O, Behague I, Herrmann SM, Mallet C, Troesch A, et al. Polymorphisms of the endothelin-A and -B receptor genes in relation to blood pressure and myocardial infarction: the Etude Cas-Temoins sur l'Infarctus du Myocarde (ECTIM) Study. Am J Hypertens 1999; 12:304-310.
33. Lajemi M, Gautier S, Poirier O, Baguet JP, Mimran A, Gosse P, et al. Endothelin gene variants and aortic and cardiac structure in never-treated hypertensives. Am J Hypertens 2001; 14:755-760.
34. Ketch T, Biaggioni I, Robertson R, Robertson D. Four faces of baroreflex failure: hypertensive crisis, volatile hypertension, orthostatic tachycardia, and malignant vagotonia. Circulation 2002; 105:2518-2523.
35. Kardos A, Rudas L, Simon J, Gingl Z, Csanady M. Effect of postural changes on arterial baroreflex sensitivity assessed by the spontaneous sequence method and Valsalva manoeuvre in healthy subjects. Clin Auton Res 1997; 7:143-148.
36. Zollei E, Paprika D, Rudas L. Measures of cardiovascular autonomic regulation derived from spontaneous methods and the Valsalva maneuver. Auton Neurosci 2003; 31:100-105.
37. Kunst AE, Groenhof F, Mackenbach JP, Health EW. Occupational class and cause specific mortality in middle aged men in 11 European countries: comparison of population based studies. EU Working Group on Socioeconomic Inequalities in Health. BMJ 1998; 316:1636-1642.
38. Bertinieri G, Di Rienzo M, Cavallazzi A, Ferrari AU, Pedotti A, Mancia G. Evaluation of baroreceptor reflex by blood pressure monitoring in unanesthetized cats. Am J Physiol 1988; 254:H377-H383.
39. Laude D, Elghozi JL, Girard A, Bellard E, Bouhaddi M, Castiglioni P, et al. Comparison of various techniques used to estimate spontaneous baroreflex sensitivity (the EuroBaVar study). Am J Physiol Regul Integr Comp Physiol 2004; 286:R226-R231.
40. Lipman RD, Salisbury JK, Taylor JA. Spontaneous indices are inconsistent with arterial baroreflex gain. Hypertension 2003; 42:481-487; E-pub 15 September 2003.
41. Parati G, Di Rienzo M, Castiglioni P, Bouhaddi M, Cerutti C, Cividjian A, et al., and the European Society of Hypertension Working Group on Blood Pressure and Heart Rate Variability. Assessing the sensitivity of spontaneous baroreflex control of the heart: deeper insight into complex physiology. Hypertension 2004; 43:e32-e34.
42. Legramante JM, Raimondi G, Massaro M, Cassarino S, Peruzzi G, Iellamo F. Investigating feed-forward neural regulation of circulation from analysis of spontaneous arterial pressure and heart rate fluctuations. Circulation 1999; 99:1760-1766.
43. Malberg H, Wessel N, Hasart A, Osterziel KJ, Voss A. Advanced analysis of spontaneous baroreflex sensitivity, blood pressure and heart rate variability in patients with dilated cardiomyopathy. Clin Sci 2002; 102:465-473.
44. Pilowsky PM, Goodchild AK. Baroreceptor reflex pathways and neurotransmitters: 10 years on. J Hypertens 2002; 20:1675-1688.
45. Pickering TG, Gribbin B, Sleight P. Comparison of the reflex heart rate response to rising and falling arterial pressure in man. Cardiovasc Res 1972; 6:277-283.
46. Iellamo F, Legramante JM, Raimondi G, Castrucci F, Massaro M, Peruzzi G. Evaluation of reproducibility of spontaneous baroreflex sensitivity at rest and during laboratory tests. J Hypertens 1996; 14:1099-1104.
47. Casadei B, Paterson DJ. Should we still use nitrovasodilators to test baroreflex sensitivity? J Hypertens 2000; 18:3-6.
48. Tank J, Baevski RM, Fender A, Baevski AR, Graves KF, Ploewka K, Weck M. Reference values of indices of spontaneous baroreceptor reflex sensitivity. Am J Hypertens 2000; 13:268-275.