Acute effect of endothelin AB antagonist on sympathetic outflow in conscious rats with heart failure

Circulation Journal

Volumn 66, Issue 9, 2002, Pages 841-845

  Tsuchiyama, Yasuko ^a   Kasamatsu, Ken ^a   Hano, Takuzo ^a   Nishio, Ichiro ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Arterial baroreflex function; Myocardial infarction; Renal sympathetic nerve activity

Indexed keywords

ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR ANTAGONIST; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; TAK 044; CYCLOPEPTIDE;

ADRENERGIC SYSTEM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEART FAILURE; HEART INFARCTION; HEART RATE; HEMODYNAMICS; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSORECEPTOR REFLEX; RAT; ANIMAL; CONGESTIVE HEART FAILURE; DISEASE MODEL; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; BAROREFLEX; DISEASE MODELS, ANIMAL; HEART FAILURE, CONGESTIVE; MALE; PEPTIDES, CYCLIC; RATS; RATS, WISTAR; SYMPATHETIC NERVOUS SYSTEM;

EID: 0036731797     PISSN: 13469843     EISSN: None     Source Type: Journal    
DOI: 10.1253/circj.66.841     Document Type: Article

References (44)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. Physiological role of endothelin-1 in nonworking muscles during exercise in healthy subjects
3. Increased endothelin in experimental heart failure
4. Role of endogenous endothelin in chronic heart failure: Effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling
5. Inhibition of myocardial endothelin pathway improves long-term survival in heart failure
6. Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits: Beneficial effects on left ventricular and myocyte function
7. Pathophysiology of chronic heart failure
8. Sympathetic activation in heart failure
9. Predicting survival for an individual with congestive heart failure using plasma norepinephrine concentration
10. Central effect of endothelin on blood pressure in conscious rats
11. Endothelin as a neuropeptide: Cardiovascular effects in the brainstem of normotensive rats
12. Beneficial effects of long-term selective endothelin type A receptor blockade in canine experimental heart failure
13. Chronic endothelin blockade in dogs with pacing-induced heart failure: Possible modulation of sympathoexcitation
14. Chronic endothelin-1 blockade reduces sympathetic activity in rabbits with heart failure
15. Pharmacology of a non-selective ET A and ET B receptor antagonist, TAK-044 and the inhibition of myocardial infarct size in rats
16. Cardiorespiratory reflex in rats with left ventricular dysfunction
17. Reflex cardiovascular control in congestive heart failure
18. Increased renal nerve activity in cardiac failure: Arterial vs. cardiac baroreflex impairment
19. ANG II receptor blockade and arterial baroreflex regulation of renal sympathetic activity in cardiac failure
20. Endothelin-induced facilitation of sympathetic neurotransmission to the rat vas deferens: Effects of suramin
21. Renal sympathetic nerve activity in mice: Comparison between mice and rats and between normal and endothelin-1 deficient mice
22. 125I] endothelin in rat and human brain
23. Autoradiographic distribution in rat tissues of binding sites for endothelin: A neuropeptide?
24. 125I] endothelin-1 binding sites in rat brain
25. Endothelin: Visualization of mRSNAs by in situ hybridization provides evidence for local action
26. Abundance of endothelin-3 in rat intestine, pituitary gland and brain
27. Endothelin concentrations in cerebrospinal fluid in depressive patients
28. Modulatory effects of endothelin-1 on cardiovascular control in rats
29. Arterial baroreflex modulation of heart rate in chronic heart failure: Clinical and hemodynamics correlates and prognostic implications
30. Angiotensin II enhances baroreflex control of sympathetic outflow in heart failure
31. Improvement in baroreflex function by an oral angiotensin receptor antagonist in rats with myocardial infarction
32. Sensitization of baroreceptor reflex by central endothelin in conscious rats
33. Endothelin-1 microinjected into nucleus tracts solitarii of rats blocks arterial baroreflexes
34. Modulatory effects of endothelin on activation in the nucleus of the solitary tract
35. Suppression of aroreceptor discharge by endothelin at high carotid sinus pressure
36. Plasma endothelin in chronic heart failure
37. Increased plasma endothelin concentrations of endothelin in congestive heart failure in humans
38. Endothelin in human congestive heart failure
39. Plasma endothelin-1 correlates with the extent of pulmonary hypertension in patients with chronic heart failure
40. Role of endothelin in the maintenance of blood pressure in conscious rats with heart failure: Acute effects of the endothelin receptor antagonist Ro 47-0203 (Bosentan)
41. The effects on hemodynamics, cardiac function, and sympathetic activity of ET AB antagonist in experimental heart failure
42. Attenuation of the baroreceptor reflex by general anesthetic agents in the normotensive rats
43. Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans
44. Renal noradrenaline spillover correlates with muscle sympathetic activity in humans