Three-dimensional in vitro reaggregates of embryonic cardiomyocytes: A potential model system for monitoring effects of bioactive agents

Journal of Biomolecular Screening

Volumn 10, Issue 8, 2005, Pages 814-822

  Bartholoma P ^a   Gorjup, E ^a   Monz, D ^a   Reininger Mack, A ^a   Thielecke, H ^a   Robitzki, A ^b  

^a FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^b Division of Molecular Biological Biochemical Processing Technology   (Germany)

Author keywords

Heart muscle spheroids; In vitro test model; Isoproterenol; Three dimensional cell culture

Indexed keywords

BETA ADRENERGIC RECEPTOR; CADHERIN; COMPLEMENTARY DNA; CONNEXIN 43; GENOMIC DNA; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE; MUSCARINIC RECEPTOR; MUSCLE PROTEIN; MYOSIN HEAVY CHAIN; RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CHICK EMBRYO; CONTROLLED STUDY; DRUG EFFECT; DRUG RESEARCH; EMBRYO; ENZYME ACTIVATION; HEART MUSCLE CELL; HIGH THROUGHPUT SCREENING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPHEROID CELL; THREE DIMENSIONAL IMAGING;

ADRENERGIC BETA-AGONISTS; ANIMALS; BIOLOGICAL MARKERS; CELL CULTURE TECHNIQUES; CHICK EMBRYO; CONNEXIN 43; DESMIN; DRUG EVALUATION, PRECLINICAL; ELECTROPHYSIOLOGY; ISOPROTERENOL; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; RNA; SPHEROIDS, CELLULAR;

ANIMALIA;

EID: 29144530591     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057105280070     Document Type: Article

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