Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin

Cell Stress and Chaperones

Volumn 10, Issue 4, 2005, Pages 285-295

  Patterson, Charles E ^a,d   Abrams, William R ^b   Wolter, Nikolaus E ^c   Rosenbloom, Joel ^b   Davis, Elaine C ^c  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c MCGILL UNIVERSITY   (Canada)

^d BAYLOR UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; COLLAGEN TYPE 1; GERANYLTRANSFERASE; IMMUNOPHILIN; MESSENGER RNA; PROTEIN; PROTEIN FKBP 65; RNA; RNA POLYMERASE II; SCLEROPROTEIN; TRANSFERASE INHIBITOR; TRANSFORMING GROWTH FACTOR BETA1; TROPOELASTIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DOWN REGULATION; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG DEVELOPMENT; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; REGULATORY MECHANISM; UPREGULATION;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CELLS, CULTURED; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX PROTEINS; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; IMMUNOPHILINS; LUNG; MICE; MICE, INBRED C57BL; PEPTIDYLPROLYL ISOMERASE; RNA STABILITY; TACROLIMUS BINDING PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMALIA;

EID: 29144462565     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1379/CSC-118R.1     Document Type: Article

References (54)

1. Benedetti C, Fabbri M, Sitia R, Cabibbo A. 2000. Aspects of gene regulation during the UPR in human cells. Biochem Biophys Res Comm 278: 530-536.
2. Betsuyaku T, Fukuda Y, Parks WC, Shipley JM, Senior RM. 2000. Gelatinase B is required for alveolar bronchiolization after intratracheal bleomycin. Am J Pathol 157: 525-535.
3. Bush KT, Hendrickson BA, Nigam SK. 1994. Induction of the FK506-binding protein, FKBP13, under conditions which misfold proteins in the endoplasmic reticulum. Biochem J 303: 705-708.
4. Capron L, Jarnet J, Heudes D, Joseph-Monrose D, Bruneval P. 1997. Repeated balloon injury of rat aorta. A model of neointima with attenuated inhibition by heparin. Arterioscler Thromb Vasc Biol 17: 1649-1656.
5. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidinium. Anal Biochem 162: 156-159.
6. Coker RK, Laurent GJ, Shahzeidi S, Lympany PA, du Bois RM, Jeffery PK, McAnulty RJ. 1997. Transforming growth factors-β1, β2, and β3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis. Am J Pathol 150: 981-991.
7. Colley NJ, Baker EK, Stamnes MA, Zuker CS. 1991. The cyclophilin homolog ninaA is required in the secretory pathway. Cell 67: 255-263.
8. Coss MC, Winterstein D, Sowder RC, Simek SL. 1995. Molecular cloning, DNA sequence analysis, and biochemical characterization of a novel 65-kDa FK506-binding protein (FKBP65). J Biol Chem 270: 29336-29341.
9. Davis EC. 1993. Stability of elastin in the developing mouse aorta: a quantitative radioautographic study. Histochemistry 100: 17-26.
10. Davis EC. 2000. FK506-binding proteins in the secretory pathway. In: Immunophilins in the Brain. FKBP Ligands: Novel Strategies for the Treatment of Neurodegenerative Disorders, ed Gold BG, Fischer G, Herdegen T. Prous Science, S.A., Barcelona, Spain, 59-66.
11. Davis EC, Broekelmann TJ, Ozawa Y, Mecham RP. 1998. Identification of tropoelastin as a ligand for the 65-kD FK506-binding protein, FKBP65, in the secretory pathway. J Cell Biol 140: 295-303.
12. Dolinski K, Muir S, Cardenas M, Heitman J. 1997. All cyclophilins and FK506 binding proteins are, individually and collectively, dispensible for viability in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 94: 13093-13098.
13. Ferreira LR, Norris K, Smith T, Hebert C, Sauk JJ. 1996. Hsp47 and other ER-resident molecular chaperones form heterocomplexes with each other and with collagen type IV chains. Connect Tissue Res 33: 265-273.
14. Galat A. 1993. Peptidylproline cis-trans-isomerases: immunophilins. Eur J Biochem 216: 689-707.
15. Hoff CR, Perkins DR, Davidson JM. 1999. Elastin gene expression is upregulated during pulmonary fibrosis. Connect Tissue Res 40: 145-153.
16. Indik Z, Yeh H, Ornstein-Goldstein N, Sheppard P, Anderson N, Rosenbloom JC, Peltonen L, Rosenbloom J. 1987. Alternative splicing of human elastin messenger-RNA indicated by sequence analysis of cloned genomic and complementary DNA. Proc Natl Acad Sci U S A 84: 5680-5684.
17. Ishii H, Mukae H, Kakugawa T, et al. 2003. Increased expression of collagen-binding heat shock protein 47 in murine bleomycin-induced pneumopathy. Am J Physiol Lung Cell Mol Physiol 285: L957-L963.
18. Jin Y-J, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ. 1991. Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A 88: 6677-6681.
19. Khalil N, Greenberg AH. 1991. The role of TGF-beta in pulmonary fibrosis. Ciba Found Symp 157: 194-207.
20. Ko MK, Kay EP. 2002. Differential interaction of molecular chaperones with procollagen I and type IV collagen in corneal endothelial cells. Mol Vis 8: 1-9.
21. Kucich U, Rosenbloom JC, Abrams WR, Rosenbloom J. 2002. Transforming growth factor-β stabilizes elastin mRNA by a pathway requiring active smads, protein kinase C-δ, and p38. Am J Respir Cell Mol Biol 26: 183-188.
22. Lamande SR, Bateman JF. 1999. Procollagen folding and assembly: the role of endoplasmic reticulum enzymes and molecular chaperones. Semin Cell Dev Biol 10: 455-464.
23. Lee AS. 1992. Mammalian stress response: induction of the glucose-regulated protein family. Curr Opin Cell Biol 4: 267-273.
24. Li DY, Brooke B, Davis EC, Mecham RP, Sorensen LK, Boak BB, Eichwald E, Keating MT. 1998. Elastin is an essential determinant of arterial morphogenesis. Nature 393: 276-280.
25. Lucey EC, Ngo HQ, Agarwal A, Smith BD, Snider GL, Goldstein RH. 1996. Differential expression of elastin and α1(I) collagen mRNA in mice with bleomycin-induced pulmonary fibrosis. Lab Investig 74: 12-20.
26. Mecham RP, Davis EC. 1994. Elastic Fiber Structure and assembly. In: Extracellular Matrix Assembly and Structure, ed Yurchenko PD, Birk DE, Mecham RP. Academic Press, San Diego, CA, 281-314.
27. Nagata K. 1996. Hsp47: a collagen-specific molecular chaperone. Trends Biochem Sci 21: 23-26.
28. 2+-binding activity. Genomics 54: 89-98.
29. Nigam SK, Jin Y-J, Jin M-J, Bush KT, Bierer BE, Burakoff SJ. 1993. Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J 294: 511-515.
30. Padilla PI, Chang M, Pacheco-Rodriguez G, Adamik R, Moss J, Vaughan M. 2003. Interaction of FK506-binding protein 13 with brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1): effects of FK506. Proc Natl Acad Sci U S A 100: 2322-2327.
31. Parks WC, Secrist H, Wu LC, Mecham RP. 1988. Developmental regulation of tropoelastin isoforms. J Biol Chem 263: 4416-4423.
32. Patterson CE, Schaub T, Coleman EJ, Davis EC. 2000. Developmental regulation of FKBP65: an ER-localized extracellular matrix binding-protein. Mol Biol Cell 11: 3925-3935.
33. Pelham HRB. 1990. The retention signal for soluble proteins of the endoplasmic reticulum. Trends Biochem Sci 15: 483-486.
34. Pittet J-F, Griffiths MJD, Geiser T, et al. 2001. TGF-β is a critical mediator of acute lung injury. J Clin Investig 107: 1537-1544.
35. Razzaque MS, Ahmed AR. 2002. Collagen, collagen-binding heat shock protein 47 and transforming growth factor-β1 are induced in cicatrical pemphigoid: possible role(s) in dermal fibrosis. Cytokine 17: 311-316.
36. Razzaque MS, Hossain MA, Kohno S, Taguchi T. 1998a. Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47. Virchows Arch 432: 455-460.
37. Razzaque MS, Nazneen A, Taguchi T. 1998b. Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung disease. Mod Pathol 11: 1183-1188.
38. Rocnik EF, van deer Veer E, Cao H, Hegele RA, Pickering JG. 2002. Functional linkage between the endoplasmic reticulum protein Hsp47 and procollagen expression in human vascular smooth muscle cells. J Biol Chem 277: 38571-38578.
39. Santana A, Saxena B, Noble NA, Gold LI, Marshall BC. 1995. Increased expression of transforming growth factor beta isoforms (beta 1, beta 2, beta 3) in bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 13: 34-44.
40. Sasaki H, Sato T, Yamauchi N, et al. 2002. Induction of heat shock protein 47 synthesis by TGF-β and IL-1β via enhancement of the heat shock element binding activity of heat shock transcription factor 1. J Immunol 168: 5178-5183.
41. Schneuwly S, Shortridge RD, Larrivee DC, Ono T, Ozaki M, Pak WL. 1989. Drosophila ninaA gene encodes an eye-specific cyclophilin (cyclosporin A binding protein). Proc Natl Acad Sci U S A 86: 5390-5394.
42. Schreiber SL. 1991. Chemistry and biology of the immunophilins and their immunosuppressive ligands. Science 251: 283-287.
43. Shadidy M, Caubit X, Olsen R, Seternes O, Moens U, Krauss S. 1999. Biochemical analysis of mouse FKBP60, a novel member of the FKBP family. Biochim Biophys Acta 1446: 295-307.
44. Shieh B-H, Stamnes MA, Seavello S, Harris GL, Zuker CS. 1989. The ninaA gene required for visual transduction in Drosophila encodes a homologue of cyclosporin A-binding protein. Nature 338: 67-70.
45. Sigal NH, Dumont FJ. 1992. Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. Annu Rev Immunol 10: 519-560.
46. Sime PJ, Xing Z, Graham FL, Csaky KG, Gauldie J. 1997. Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung. J Clin Investig 100: 768-776.
47. Smith T, Ferreira LR, Hebert C, Norris K, Sauk JJ. 1995. Hsp47 and cyclophilin B traverse the endoplasmic reticulum with procollagen into pre-Golgi intermediate vesicles. J Biol Chem 270: 18323-18328.
48. Steinmann B, Bruckner P, Superti-Furga A. 1991. Cyclosporin A slows collagen triple-helix formation in vivo: indirect evidence for a physiologic role of peptidyl-prolyl cis-trans-isomerase. J Biol Chem 266: 1299-1303.
49. Swiderski RE, Dencoff JE, Floerchinger CS, Shapiro SD, Hunninghake GW. 1998. Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis. Am J Pathol 152: 821-828.
50. Tasab M, Batten MR, Bulleid NJ. 2000. HSP47: a molecular chaperone that interacts with and stabilizes correctly-folded procollagen. EMBO J 19: 2204-2211.
51. Thrall RS, Scalise PJ. 1995. Bleomycin. In: Pulmonary Fibrosis, ed Phan SH. Marcel Dekker, New York, NY, 231-292.
52. Wendel DP, Taylor DG, Albertine KH, Keating MT, Li DY. 2000. Impaired distal airway development in mice lacking elastin. Am J Respir Cell Mol Biol 23: 320-326.
53. Yamamura I, Hirata H, Hosokawa N, Nagata K. 1998. Transcriptional activation of the mouse HSP47 gene in mouse osteoblast MC3T3-E1 cells by TGF-β1. Biochem Biophys Res Comm 244: 68-74.
54. Zhang K, Phan SH. 1996. Cytokines and pulmonary fibrosis. Biol Signals 5: 232-239.