Changes in heart rate variability are correlated to hemodynamic improvement with chronic CARVEDILOL therapy in heart failure

Journal of Cardiac Failure

Volumn 11, Issue 9, 2005, Pages 693-699

  Bullinga, John R ^a   Alharethi, Rami ^b   Schram, Mark S ^b   Bristow, Michael R ^c   Gilbert, Edward M ^b  

^a NEW YORK UNIVERSITY   (United States)

^b UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

adrenergic antagonist; Carvedilol; Congestive heart failure; Heart rate variability

Indexed keywords

CARVEDILOL; NORADRENALIN;

ADULT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CLINICAL ARTICLE; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY SINUS; CORRELATION ANALYSIS; DOUBLE BLIND PROCEDURE; FEMALE; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE EJECTION FRACTION; HEART RATE; HEART RATE VARIABILITY; HOLTER MONITORING; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; AGED, 80 AND OVER; CARBAZOLES; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY, AMBULATORY; FEMALE; HEART FAILURE, CONGESTIVE; HEART RATE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; PROPANOLAMINES; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 29144455179     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2005.06.435     Document Type: Article

References (49)

1. J.N. Cohn, T.B. Levine, and M.T. Olivari Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure N Engl J Med 1984 311 1984 819 823
2. G.C. Francis, S.R. Goldsmith, T.B. Levine, M.T. Olivari, and J.N. Cohn The neurohumoral axis in congestive heart failure Ann Intern Med 101 1984 370 377
3. D.L. Eckberg, M. Drabinsky, and E. Braunwald Defective cardiac parasympathetic control in patients with heart disease N Engl J Med 285 1971 877 883
4. M.R. Bristow β-Adrenergic receptor blockade in chronic heart failure Circulation 101 2000 558 569
5. The SOLVD investigators Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions N Engl J Med 10 1992 685 691
6. B. Pitt, F. Zannad, W.J. Remme, R. Cody, A. Castaigne, and A. Perez The effect of spironolactone on morbidity and mortality in patients with severe heart failure N Engl J Med 10 1999 709 717
7. M. Packer, M.R. Bristow, J.N. Cohn, W. Colucci, M. Fowler, E.M. Glibert, and N. Shusterman The effect of carvedilol on morbidity and mortality in patients with chronic heart failure N Engl J Med 334 1996 1349 1355
8. Carvedilol Prospective Randomized Cumulative Survival Study Group Effect of Carvedilol on Survival in Severe Chronic Heart Failure N Engl J Med 344 2001 1651 1658
9. CIBIS-II Investigators and Committees The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomized trial Lancet 353 1999 9 13
10. MERIT-HF Study Group Effect of Metoprolol CR/XL in chronic congestive heart failure: Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF) Lancet 353 1999 2001 2007
11. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology Heart rate variability - standards of measurement, physiologic interpretation, and clinical use Circulation 93 1996 1043 1065
12. M.T. La Rovere, J.T. Bigger, F.I. Marcus, A. Mortara, P.J. Schwartz, and for the ATRAMI Investigators Baroreflex sensitivity and heart rate variability in prediction of total cardiac mortality after myocardial infarction Lancet 351 1998 478 484
13. P. Ponikowski, S.D. Anker, T.P. Chua, R. Szelemej, M. Piepoli, and S. Adamopoulos Depressed heart rate variability as an independent predictor of death in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy Am J Cardiol 79 1997 1645 1650
14. B. Szabo, D.J. Veldhuisen, N. Van der Veer, J. Brouwer, P.A. De Graeff, and H.J. Crijns Prognostic value of heart rate variability in chronic congestive heart failure secondary to idiopathic or ischemic dilated cardiomyopathy Am J Cardiol 1997 978 980
15. G. Yi, J.H. Goldman, P.J. Keeling, M. Reardon, W.J. McKenna, and M. Malik Heart rate variability in idiopathic dilated cardiomyopathy: relation to disease severity and prognosis Heart 77 1997 108 114
16. J. Nolan, P.D. Batin, R. Andrews, S.J. Lindsay, P. Brooksby, and M. Mullen Prospective study of heart rate variability and mortality in chronic heart failure: Results of the United Kingdom Heart Failure Evaluation and Assessment of Risk Trial (UK-Heart) Circulation 98 1998 1510 1516
17. P.F. Binkley, G.J. Haas, R.C. Starling, E. Nunziata, P.A. Hatton, and C.V. Leier Sustained augmentation of parasympathetic tone with angiotensin-converting enzyme inhibition in patients with congestive heart failure J Am Coll Cardiol 21 1993 655 661
18. A.D. Flapan, J. Nolan, J.M.M. Neilson, and D.J. Ewing Effect of captopril on cardiac parasympathetic activity in chronic cardiac failure secondary to coronary artery disease Am J Cardiol 69 1992 532 535
19. H. Krum, J.T. Bigger, R.L. Goldsmith, and M. Packer Effect of long-term digoxin therapy on autonomic function in patients with chronic heart failure J Am Coll Cardiol 25 1995 289 294
20. J.L. Lin, H.L. Chan, C.C. Du, I.N. Lin, C.W. Lai, and K.T. Lin Long-term beta-blocker therapy improves autonomic nervous regulation in advanced congestive heart failure: a longitudinal heart rate variability study Am Heart J 137 1999 658 665
21. K. Jansson, I. Hagerman, R. Ostlund, K.E. Karlberg, E. Nylander, and O. Nyquist The effects of metoprolol and captopril on heart rate variability in patients with idiopathic dilated cardiomyopathy Clin Cardiol 22 1999 397 402
22. F. Pousset, X. Copie, P. Lechat, P. Jaillon, J.P. Boissel, and M. Hetzel Effects of bisoprolol on heart rate variability in heart failure Am J Cardiol 77 1996 612 617
23. R.L. Goldsmith, J.T. Bigger, D.M. Bloomfield, H. Krum, R.C. Steinman, and J. Sackner-Bernstein Long-term carvedilol therapy increases parasympathetic nervous system activity in chronic congestive heart failure Am J Cardiol 80 1997 1101 1104
24. K. Strein, G. Sponer, B. Muller-Beckmann, and W. Bartsch Pharmacological profile of carvedilol, a compound with β-blocking and vasodilating properties J Cardiovasc Pharmacol 10 Suppl 11 1987 S33 S41
25. R.R. Ruffolo, M. Gelai, J.P. Hieble, R.N. Willette, and A.J. Nichols The pharmacology of carvedilol Eur J Clin Pharmacol 38 Suppl 2 1990 502 508
26. S.L. Olsen, E.M. Gilbert, D.G. Renlund, D.O. Taylor, F.D. Yanowitz, and M.R. Bristow Carvedilol improves left ventricular function and symptoms in chronic heart failure: a double-blind randomized study J Am Coll Cardiol 25 1995 1225 1231
27. H. Krum, J.D. Sackne-Bernstein, R.L. Goldsmith, M.L. Kukin, B. Schwartz, and J. Penn Double-blind, placebo-controlled study of long-term efficacy carvedilol in patients with severe chronic heart failure Circulation 92 1995 1499 1506
28. M. Metra, Nardi, R. Giubbini, and L. Dei Cas Effects of short- and long-term carvedilol administration on rest and exercise hemodynamic variables, exercise capacity and clinical conditions in patients with idiopathic dilated cardiomyopathy J Am Coll Cardiol 24 1994 1678 1687
29. S. Guzzetti, C. Cogliati, M. Turiel, C. Crema, F. Lombardi, and A. Malliani Sympathetic predominance followed by functional denervation in the progression of chronic heart failure Eur Heart J 16 1995 1100 1107
30. H. Tsuji, M.G. Larson, F.J. Venditti Jr., E.S. Manders, J.C. Evans, and C.L. Feldman Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study Circulation 94 1996 2850 2855
31. J. Hoffmann, W. Grimm, V. Menz, H.H. Muller, and B. Maisch Heart rate variability and baroreflex sensitivity in idiopathic dilated cardiomyopathy Heart 83 2000 531 536
32. H.V. Huikuri, T. Makikallio, K.E. Airaksinen, R. Mitrani, A. Castellanos, and R.J. Myerburg Measurement of heart rate variability: a clinical tool or a research toy? J Am Coll Cardiol 34 1999 1878 1883
33. M.G. Kienzle, D.W. Ferguson, C.L. Birkett, G.A. Myers, W.J. Berg, and D.J. Mariano Clinical, hemodynamic and sympathetic neural correlates of heart rate variability in congestive heart failure Am J Cardiol 69 1992 761 767
34. T. Yoshikawa, A. Baba, M. Akaishi, H. Mitamura, S. Ogawa, and M. Suzuki Neurohumoral activations in congestive heart failure: correlations with cardiac function, heart rate variability, and baroreceptor sensitivity Am Heart J 137 1999 666 671
35. S. Challapalli, A.H. Kadish, G. Horvath, and J.J. Goldberger Differential effects of parasympathetic blockade and parasympathetic withdrawal on heart rate variability J Cardiovasc Electrophysiol 10 1999 1192 1199
36. M. Rocchetti, G. Malfatto, F. Lombardi, and A. Zaza Role of the input/output relation of sinoatrial myocytes in cholinergic modulation of heart rate variability J Cardiovasc Electrophysiol 11 2000 522 530
37. A. Mortara, P. Sleight, G.D. Pinna, R. Maestri, A. Prpa, and M.T. La Rouvere Abnormal awake respiratory patterns are common in chronic congestive heart failure and may prevent evaluation of autonomic tone by measures of heart rate variability Circulation 96 1997 246 252
38. L. Bernadi, F. Valle, M. Coco, A. Calciati, and P. Sleight Physical activity influences heart rate variability and very-low-frequency components in Holter electrograms Cardiovasc Res 32 1996 234 237
39. P. Van de Borne, N. Montano, M. Pagani, R. Oren, and V.K. Somers Absence of low-frequency variability of sympathetic nerve activity in severe heart failure Circulation 95 1997 1449 1454
40. A.J. Burger, and D. Aronson Effect of vasoactive therapy on heart rate variability in patients with acutely decompensated congestive heart failure Am J Cardiol 84 1999 476 478
41. P.D. Batin, and J. Nolan Assessment of autonomic function: reflex testing or variability analysis? J Amb Mon 9 1996 255 273
42. The Task Force on Heart Failure at the European Society of Cardiology Guidelines for the diagnosis of heart failure Eur Heart J 16 1995 741 751
43. G. Yi, M.M. Gallagher, Y.G. Yap, X.H. Guo, R. Harrison, and J.T. McDonald Consistency of multicenter measurements of heart rate variability in survivors of acute myocardial infarction PACE 23 2000 157 164
44. J.A. Taylor, D.L. Carr, C.W. Myers, and D.L. Eckberg Mechanisms underlying very-low-frequency RR-interval oscillations in humans Circulation 98 1998 547 555
45. M. Pagani, N. Montano, A. Porta, A. Malliani, F.M. Abboud, and C. Birkett Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans Circulation 95 1997 1441 1448
46. D.L. Eckberg Sympathovagal balance: a critical appraisal Circulation 96 1997 3224 3232
47. A.E. Hedman, J.D. Poloniecki, A.J. Camm, and M. Malik Relation of mean heart rate and heart rate variability in patients with left ventricular dysfunction Am J Cardiol 84 1999 225 228
48. E.M. Gilbert, W.T. Abraham, S. Olsen, B. Hattler, M. White, and P. Mealy Comparative hemodynamic, left ventricular function, and antiadrenergic effects of chronic treatment with metoprolol versus carvedilol in failing heart Circulation 94 1996 2817 2825
49. E.R. Azevedo, T. Kubo, S. Mak, A. Al-Hesayen, A. Schofield, and R. Allan Nonselective versus selective β-adrenergic receptor blockade in congestive heart failure: differential effects on sympathetic activity Circulation 104 2001 2194 2199