The fibrinolysis inhibitor α2-antiplasmin in the human cornea

Current Eye Research

Volumn 30, Issue 12, 2005, Pages 1097-1103

  Ayala, Aidee ^a   Warejecka, Debra J ^a   Vaughan, Kimberly A ^a   Twining, Sally S ^a   Yue, Beatrice Y J T ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

Author keywords

2 antiplasmin; Cornea; Fibrinolysis; Plasmin; Serpin

Indexed keywords

ALPHA 2 ANTIPLASMIN; ANTIFIBRINOLYTIC AGENT; COMPLEMENTARY DNA; MESSENGER RNA; RNA; ANTIPLASMIN;

ADULT; AGED; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORNEA; CORNEA ENDOTHELIUM; CORNEA EPITHELIUM; CORNEA STROMA; DNA SEQUENCE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; WESTERN BLOTTING; ADOLESCENT; ENZYME IMMUNOASSAY; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIFIBRINOLYTIC AGENTS; ANTIPLASMIN; BASE SEQUENCE; BLOTTING, WESTERN; CORNEAL STROMA; ENDOTHELIUM, CORNEAL; EPITHELIUM, CORNEAL; HUMANS; IMMUNOBLOTTING; IMMUNOENZYME TECHNIQUES; MIDDLE AGED; MOLECULAR SEQUENCE DATA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 29144449414     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1080/02713680500403046     Document Type: Article

References (42)

1. Li W-Y, Chong SSN, Huang EY, Tuan T-L. Plasminogen activator/plasmin system: a major player in wound healing? Wound Repair Regen. 2003;11:239-247.
2. Berta A, Tozser J, Holley FJ. Determination of plasminogen activator activities in normal and pathological human tears. The significance of tear plasminogen activators in the inflammatory and traumatic lesions of the cornea and the conjunctiva. Acta Ophthalmol. 1990;68:508-514.
3. Twining SS, Wilson PM, Ngamkitidechakul C. Extrahepatic synthesis of plasminogen in the human cornea is up-regulated by interleukins-1α and -1β. Biochem J. 1999;339:705-712.
4. Twining SS, Schulte DP, Zhou X, et al. Changes in rat corneal matrix metalloproteinases and serine proteinases under vitamin A deficiency. Curr Eye Res. 1997;16:158-165.
5. Tao Y, Bazan HE, Bazan NG. Platelet-activating factor enhances urokinase-type plasminogen activator gene expression in corneal epithelium. Invest Ophthalmol Vis Sci. 1996;37:2037-2046.
6. Ramsby ML, Kreutzer DL. Fibrin induction of tissue plasminogen activator expression in corneal endothelial cells in vitro. Invest Ophthalmol Vis Sci. 1993;34:3207-3219.
7. Wang Z, Kurpakus-Wheater M. Decreased plasminogen activator inhibitor-1 secretion in hypoxic corneal epithelial cells is associated with increased urokinase plasminogen activator activity. Int J Biochem Cell Biol. 2003;35:339-348.
8. Berman M. The pathogenesis of corneal epithelial defects. Acta Ophthalmol Suppl. 1989;192:55-64.
9. Berman M, Leary R, Gage J. Evidence for a role of the plasminogen activator-plasmin system in corneal ulceration. Invest Ophthalmol Vis Sci. 1980;19:1204-1221.
10. Kao WW, Kao CW, Kaufman AH, et al. Healing of corneal epithelial defects in plasminogen- and fibrinogen-deficient mice. Invest Ophthalmol Vis Sci. 1998;39:502-508.
11. Drew AF, Schiman HL, Kombrinck KW, et al. Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice. Invest Ophthalmol Vis Sci. 2000;41:67-72.
12. Watanabe M, Yano W, Kondo S, et al. Up-regulation of urokinase-type plasminogen activator in corneal epithelial cells induced by wounding. Invest Ophthalmol Vis Sci. 2003;44:3332-3338.
13. Morimoto K, Mishima H, Nishida T, Otori T. Role of urokinase type plasminogen activator (u-PA) in corneal epithelial migration. Thromb Haemost. 1993;69:387-391.
14. Tozser J, Berta A. Plasminogen activator inhibitors in human tears. Acta Ophthalmol. 1991;69:426-431.
15. Williams DL, Risse B, Kim S, Saunders D, et al. Plasminogen activator inhibitor type 2 in human corneal epithelium. Invest Ophthalmol Vis Sci. 1999;40:1669-1675.
16. Tervo T, Tervo K, van Setten GB, et al. Plasminogen activator and its inhibitor in the experimental corneal wound. Exp Eye Res. 1989;48:445-449.
17. Sawaguchi S, Twining SS, Yue BY, et al. α2-Macroglobulin levels in normal human and keratoconus corneas. Invest Ophthalmol Vis Sci. 1994;35:4008-4014.
18. Twining SS, Fukuchi T, Yue BY, et al. Corneal synthesis of α1-proteinase inhibitor (α1-antitrypsin). Invest Ophthalmol Vis Sci. 1994;35:458-462.
19. Kolev K, Lerant I, Tenekejiev K, Machovich R. Regulation of fibrinolytic activity of neutrophil leukocyte elastase, plasmin, and miniplasmin by plasma protease inhibitors. J Biol Chem. 1994;269:17030-17034.
20. Gettins PGW. Serpin structure, mechanism and function. Chem Rev. 2002;102:4751-4804.
21. Frank PS, Douglas JT, Locher M, et al. Structural/functional characterization of the α2-plasmin inhibitor C-terminal peptide. Biochemistry. 2003;42:1078-1085.
22. Bangert K, Johnsen AH, Christensen U, Thorsen S. Different N-terminal forms of alpha 2-plasmin inhibitor in human plasma. Biochem J. 1993;291:623-625.
23. Twining SS, Fukuchi T, Yue BYJT, et al. α2-Macroglobulin, is present in and synthesized by the cornea. Invest Ophthalmol Vis Sci. 1994;35:3226-3233.
24. Twining SS, Everse SJ, Wilson PM, et al. Localization and quantification of α-1-proteinase inhibitor in the human cornea. Curr Eye Res. 1989;8:389-395.
25. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265-275.
26. Cesarone CF, Bolognesi C, Santi L. Improved microfluorometric DNA determination in biological material using 33258 Hoechst. Anal Biochem. 1979;100:188-197.
27. Griffith M, Osborne R, Munger R, et al. Functional human corneal equivalents constructed from cell lines. Science. 1999;286:2169-2172.
28. Watsky MA, Griffith M, Wang D-A, Tigyi GJ. Phospholipid growth factors and corneal wound healing. Ann NY Acad Sci. 2000;905:142-158.
29. Ngamkitidechakul C, Warejcka DJ, Burke JM, O'Brien WJ, Twining SS. Sufficiency of the reactive site loop of maspin for induction of cell-matrix adhesion and inhibition of cell invasion: conversion of ovalbumin to a maspin-like molecule. J Biol Chem. 2003;278:31796-31806.
30. Twining SS, Fukuchi T, Yue BYJT, et al. α1-Antichymotrypsin is present in and synthesized by the cornea. Curr Eye Res. 1994;13:433-439.
31. Lee KN, Lee CS, Tae W-C, et al. Cross-linking of wild-type and mutant α2-antiplasmins to fibrin by activated factor XIII and by a tissue transglutaminase. J Biol Chem. 2000;275:37382-37389.
32. Saito H, Goldsmith GH, Moroi M, Aoki N. Inhibitory spectrum of α2-plasmin inhibitor. Proc Natl Acad Sci USA. 1979;76:2013-2017.
33. Rijken DC, Juhan-Vague I, Collen D. Complexes between tissue-type plasminogen activator and proteinase inhibitors in human plasma, identified with an immunoradiometric assay. J Lab Clin Med. 1983;101:285-294.
34. Le DM, Besson A, Fogg DK, et al. Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade. J Neurosci. 2003;23:4034-4043.
35. Monea S, Lehti K, Keski-Oja J, Mignatti P. Plasmin activates pro-matrix metalloproteinase-2 with a membrane-type 1 matrix metalloproteinase-dependent mechanism. J Cell Physiol. 2002;192:160-170.
36. Davis GE, Pintar AKA, Salazar R, Maxwell SA. Matrix metalloproteinase-1 and -9 activation by plasmin regulates a novel endothelial cell-mediated mechanism of collagen gel contraction and capillary tube regression in three-dimensional collagen matrices. J Cell Sci. 2001;114:917-930.
37. Andreasen P, Kjoller L, Christensen L, Duffy MJ. The urokinase-type plasminogen activator system in cancer metastasis. Int J Cancer. 1997;72:1-22.
38. Krishnan S, Deora AB, Annes JP, et al. Annexin II-mediated plasmin generation activates TGF-β3 during epithelial-mesenchymal transformation in the developing avian heart. Dev Biol. 2004;265:140-154.
39. Matsuno H, Kozawa O, Yoshimi N, et al. Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction. Blood. 2002;100:2487-2493.
40. Salonen EM, Tervo T, Torma E, et al. Plasmin in tear fluid of patients with corneal ulcers: basis for new therapy. Acta Ophthalmol. 1987;65:3-12.
41. Virtanen T, Honkanen N, Harkonen M, et al. Elevation of tear fluid plasmin activity of contact lens wearers studied with a rapid fluorometric assay. Cornea. 1994;13:210-213.
42. Cejkova J, Lojda Z, Vacik J, et al. Histochemical changes in the rabbit cornea and plasmin activity in the tear fluid during contact lens wear. Favourable influence of protease inhibitors (aprotinin, PC5, elastatinal). Histochemistry. 1992;97:69-76.