메뉴 건너뛰기




Volumn 56, Issue 4, 2005, Pages 363-371

Facts about nicotine toxicity

Author keywords

Acute toxicity; Exposure; Long term toxicity; NOAEL; Risk estimation; Risk evaluation

Indexed keywords

ALKALOID; COTININE; NICOTINE; TOBACCO SMOKE;

EID: 29044444709     PISSN: 00041254     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (60)

References (57)
  • 1
    • 0020460365 scopus 로고
    • Nicotine, resorption and fate
    • Schevelbein H. Nicotine, resorption and fate. Pharm Ther 1982;18:233-48.
    • (1982) Pharm Ther , vol.18 , pp. 233-248
    • Schevelbein, H.1
  • 2
    • 0027219721 scopus 로고
    • Gas chromatographic-mass spectrometric method for determination of anabasine, anatabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users
    • Jacob P 3rd, Yu L, Liang G, Shulgin AT, Benowitz NL. Gas chromatographic-mass spectrometric method for determination of anabasine, anatabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users. J Chromatogr 1993;619:49-61.
    • (1993) J Chromatogr , vol.619 , pp. 49-61
    • Jacob III, P.1    Yu, L.2    Liang, G.3    Shulgin, A.T.4    Benowitz, N.L.5
  • 3
    • 32544432806 scopus 로고    scopus 로고
    • World Health Organization; Geneva
    • WHO. An international treaty for tobacco control. World Health Organization. Geneva; 2003 [cited 10 June 2005], Available from: http://www.who.int/features/2003/
    • (2003) An International Treaty for Tobacco Control
  • 5
    • 1942532837 scopus 로고    scopus 로고
    • Nicotine, its metabolism and an overview of its biological effects
    • Yildiz D. Nicotine, its metabolism and an overview of its biological effects. Toxicon 2004;43:619-32.
    • (2004) Toxicon , vol.43 , pp. 619-632
    • Yildiz, D.1
  • 7
    • 0022297887 scopus 로고
    • Suicide plan by nicotine poisoning: A review of nicotine toxicity
    • Saxena K, Scheman A. Suicide plan by nicotine poisoning: A review of nicotine toxicity. Vet Hum Toxicol 1985;27:495-7.
    • (1985) Vet Hum Toxicol , vol.27 , pp. 495-497
    • Saxena, K.1    Scheman, A.2
  • 8
    • 0023248707 scopus 로고
    • Prolonged absorption with development of tolerance to toxic effects following cutaneous exposure to nicotine
    • Benowitz NL, Lake T, Keller KH, Lee BL. Prolonged absorption with development of tolerance to toxic effects following cutaneous exposure to nicotine. Clin Pharmacol Ther 1987;42:119-20.
    • (1987) Clin Pharmacol Ther , vol.42 , pp. 119-120
    • Benowitz, N.L.1    Lake, T.2    Keller, K.H.3    Lee, B.L.4
  • 10
    • 0030885491 scopus 로고    scopus 로고
    • A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes
    • Messina ES, Tyndale RF, Sellers EM. A major role for CYP2A6 in nicotine C-oxidation by human liver microsomes. J. Pharmacol Exp Ther 1997;282:1608-14.
    • (1997) J. Pharmacol Exp Ther , vol.282 , pp. 1608-1614
    • Messina, E.S.1    Tyndale, R.F.2    Sellers, E.M.3
  • 11
    • 0002097119 scopus 로고
    • Human pharmacology of nicotine
    • Cappell HD et al. (eds.). New York: Plenum Press
    • Benowitz NL. Human pharmacology of nicotine. In: Cappell HD et al. (eds.) Research Advances in Alcohol and Drug Problems, Volume 9. New York: Plenum Press; 1986.
    • (1986) Research Advances in Alcohol and Drug Problems , vol.9
    • Benowitz, N.L.1
  • 12
    • 0036061470 scopus 로고    scopus 로고
    • Smoking during pregnancy: A way to transfer the addiction to the next generation?
    • Hellstrom-Lindahl E, Nordberg A. Smoking during pregnancy: a way to transfer the addiction to the next generation? Respiration 2002;69:289-93.
    • (2002) Respiration , vol.69 , pp. 289-293
    • Hellstrom-Lindahl, E.1    Nordberg, A.2
  • 13
    • 0026542485 scopus 로고
    • Nicotine excretion by the apocrine and eccrine sweat in smokers and passive smokers
    • Balabanova S, Buhler G, Schneider E, Boschek HJ, Schneitler H. Nicotine excretion by the apocrine and eccrine sweat in smokers and passive smokers. Hautarzt 1992;43:73-6.
    • (1992) Hautarzt , vol.43 , pp. 73-76
    • Balabanova, S.1    Buhler, G.2    Schneider, E.3    Boschek, H.J.4    Schneitler, H.5
  • 14
    • 0027378475 scopus 로고
    • Rates of excretion of cotinine, nicotine glucuronide, and 3-hydroxycotinine glucuronide in rat bile
    • Seaton MJ, Kyerematen GA, Vesell ES. Rates of excretion of cotinine, nicotine glucuronide, and 3-hydroxycotinine glucuronide in rat bile. Drug Metab Dispos 1993;21:927-32.
    • (1993) Drug Metab Dispos , vol.21 , pp. 927-932
    • Seaton, M.J.1    Kyerematen, G.A.2    Vesell, E.S.3
  • 15
    • 0022178208 scopus 로고
    • Nicotine and cotinine concentrations in serum and urine of infants exposed via passive smoking or milk from smoking mothers
    • Luck W, Nau H. Nicotine and cotinine concentrations in serum and urine of infants exposed via passive smoking or milk from smoking mothers. J Pediatr 1985;107:816-20.
    • (1985) J Pediatr , vol.107 , pp. 816-820
    • Luck, W.1    Nau, H.2
  • 16
    • 0021882484 scopus 로고
    • Nicotine renal excretion rate influences nicotine intake during cigarette smoking
    • Benowitz NL, Jacob P. Nicotine renal excretion rate influences nicotine intake during cigarette smoking. J Pharmacol Exp Ther 1985;234:153-5.
    • (1985) J Pharmacol Exp Ther , vol.234 , pp. 153-155
    • Benowitz, N.L.1    Jacob, P.2
  • 17
    • 0013845263 scopus 로고
    • Significance of smoking in investigation of urinary excretion rates of amines in man
    • Becket AH, Rowland M, Triggs EJ. Significance of smoking in investigation of urinary excretion rates of amines in man. Nature 1965;207:200-1.
    • (1965) Nature , vol.207 , pp. 200-201
    • Becket, A.H.1    Rowland, M.2    Triggs, E.J.3
  • 18
    • 0031979685 scopus 로고    scopus 로고
    • Urinary cotinine as a tobacco-smoke exposure index: A minireview
    • Haufroid V, Lison D. urinary cotinine as a tobacco-smoke exposure index: a minireview. Int Arch Occup Envirom Health 1998;71:162-8.
    • (1998) Int Arch Occup Envirom Health , vol.71 , pp. 162-168
    • Haufroid, V.1    Lison, D.2
  • 19
    • 0036142016 scopus 로고    scopus 로고
    • Is the hair nicotine level a more accurate biomarker of environmental tobacco smoke exposure than urine cotinine?
    • Al-Delaimy WK, Crane J, Woodward A. Is the hair nicotine level a more accurate biomarker of environmental tobacco smoke exposure than urine cotinine? J Epidemiol Community Health 2002;56:66-71.
    • (2002) J Epidemiol Community Health , vol.56 , pp. 66-71
    • Al-Delaimy, W.K.1    Crane, J.2    Woodward, A.3
  • 20
    • 0030880002 scopus 로고    scopus 로고
    • Analysis of nicotine and cotinine in the hair of hospitality workers exposed to environmental tobacco smoke
    • Dimich-Ward H, Gee H, Brauer M, Leung V. Analysis of nicotine and cotinine in the hair of hospitality workers exposed to environmental tobacco smoke. J Occup Environ Med 1997;39:946-8.
    • (1997) J Occup Environ Med , vol.39 , pp. 946-948
    • Dimich-Ward, H.1    Gee, H.2    Brauer, M.3    Leung, V.4
  • 21
    • 1642361748 scopus 로고    scopus 로고
    • Measuring tobacco smoke exposure: Quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods
    • Dhar P. Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal 2004;35:155-68.
    • (2004) J Pharm Biomed Anal , vol.35 , pp. 155-168
    • Dhar, P.1
  • 25
    • 0020607506 scopus 로고
    • Genetics of nicotine response in four inbred strains of mice
    • Marks MH, Burch JB, Collins AC. Genetics of nicotine response in four inbred strains of mice. J Pharmacol Exp Ther 1983;226:291-302.
    • (1983) J Pharmacol Exp Ther , vol.226 , pp. 291-302
    • Marks, M.H.1    Burch, J.B.2    Collins, A.C.3
  • 27
    • 29044447713 scopus 로고    scopus 로고
    • US-EPA. Chemical profile: Nicotine. US Environmental Protection Agency; 1987
    • US-EPA. Chemical profile: Nicotine. US Environmental Protection Agency; 1987.
  • 28
    • 84904292773 scopus 로고
    • NIOSH: Documentation for Immediately Dangerous to Life or Health Concentrations (IDLH)
    • National Institute for Occupational Safety and Health
    • NIOSH: Documentation for Immediately Dangerous to Life or Health Concentrations (IDLH). Nicotine. National Institute for Occupational Safety and Health; 1994.
    • (1994) Nicotine
  • 29
    • 0020627161 scopus 로고
    • Acute intoxication with nicotine alkaloids and cannabinoids in children from ingestion of cigarettes
    • Malizia E, Andreucci G, Alfani F, Smeriglio M, Nicholai P. Acute intoxication with nicotine alkaloids and cannabinoids in children from ingestion of cigarettes. Hum Toxicol 1983;2:315-6.
    • (1983) Hum Toxicol , vol.2 , pp. 315-316
    • Malizia, E.1    Andreucci, G.2    Alfani, F.3    Smeriglio, M.4    Nicholai, P.5
  • 30
    • 84965339203 scopus 로고
    • The health consequences of smoking: Chronic obstructive lung disease
    • U.S. Department of Health and Human Services, Public Health Service, Office on Smoking and Health. DHHS Publication No. (PHS) 84-50205
    • U.S. Department of Health and Human Services. The Health Consequences of Smoking: Chronic Obstructive Lung Disease. A Report of the Surgeon General. U.S. Department of Health and Human Services, Public Health Service, Office on Smoking and Health. DHHS Publication No. (PHS) 84-50205; 1984.
    • (1984) A Report of the Surgeon General
  • 32
  • 33
    • 0029760877 scopus 로고    scopus 로고
    • The maternal and fetal physiologic effects of nicotine
    • Lambers DS, Clark KE. The maternal and fetal physiologic effects of nicotine. Semin Perinatol 1996;20:115-26.
    • (1996) Semin Perinatol , vol.20 , pp. 115-126
    • Lambers, D.S.1    Clark, K.E.2
  • 34
    • 0025766683 scopus 로고
    • Smoking and buccally administered nicotine. Acute effect on uterine and umbilical artery Doppler flow velocity waveforms
    • Bruner JP, Forouzan I. Smoking and buccally administered nicotine. Acute effect on uterine and umbilical artery Doppler flow velocity waveforms. J Reprod Med 1991;36:435-40.
    • (1991) J Reprod Med , vol.36 , pp. 435-440
    • Bruner, J.P.1    Forouzan, I.2
  • 37
    • 84937101225 scopus 로고
    • Mental development of children whose mothers smoked during pregnancy
    • Naeye RL, Peters EC. Mental development of children whose mothers smoked during pregnancy. Obstet Gynecol 1984;64:601-7.
    • (1984) Obstet Gynecol , vol.64 , pp. 601-607
    • Naeye, R.L.1    Peters, E.C.2
  • 39
    • 0025054597 scopus 로고
    • Assessment of genotoxicity of nicotine employing in vitro mammalian test systems
    • Trivedi AH, Dave BJ, Adhvaryu SG. Assessment of genotoxicity of nicotine employing in vitro mammalian test systems. Cancer Lett 1990;54:89-94.
    • (1990) Cancer Lett , vol.54 , pp. 89-94
    • Trivedi, A.H.1    Dave, B.J.2    Adhvaryu, S.G.3
  • 40
    • 0003448477 scopus 로고
    • The health consequences of involuntary smoking
    • Atlanta: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. DHHS Publication No. (CDC) 88-8406
    • U.S. Department of Health and Human Services. The Health Consequences of Involuntary Smoking. A Report of the Surgeon General. Atlanta: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health. DHHS Publication No. (CDC) 88-8406; 1988.
    • (1988) A Report of the Surgeon General
  • 41
    • 0025245549 scopus 로고
    • Cigarette smoking and endothelial injury: A review
    • Pittilo RM. Cigarette smoking and endothelial injury: a review. Adv Exp Med Biol 1990;273:61-78.
    • (1990) Adv Exp Med Biol , vol.273 , pp. 61-78
    • Pittilo, R.M.1
  • 42
    • 0029820141 scopus 로고    scopus 로고
    • Nicotine enhances expression of the neutrophil elastase gene and protein in a human myeloblast/promyelocyte cell line
    • Armstrong LW, Rom WN, Martiniuk FT, Hart D, Jagirdar J, Galdston M. Nicotine enhances expression of the neutrophil elastase gene and protein in a human myeloblast/promyelocyte cell line. Am J Respir Crit Care Med 1996;154:1520-4.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 1520-1524
    • Armstrong, L.W.1    Rom, W.N.2    Martiniuk, F.T.3    Hart, D.4    Jagirdar, J.5    Galdston, M.6
  • 43
    • 0028301357 scopus 로고
    • Inhaled nicotine in humans: Effect on the respiratory and cardiovascular systems
    • Hansson L, Choudry NB, Karlsson JA, Fuller RW. Inhaled nicotine in humans: effect on the respiratory and cardiovascular systems. J Appl Physiol 1994;76:2420-7.
    • (1994) J Appl Physiol , vol.76 , pp. 2420-2427
    • Hansson, L.1    Choudry, N.B.2    Karlsson, J.A.3    Fuller, R.W.4
  • 45
    • 0024506829 scopus 로고
    • Neuroendocrine actions of nicotine and of exposure to cigarette smoke: Medical implications
    • Fuxe K, Andersson K, Eneroth P, Harfstrand A, Agnati L. Neuroendocrine actions of nicotine and of exposure to cigarette smoke: medical implications. Psychoneuroendocrinology 1989;14:19-41.
    • (1989) Psychoneuroendocrinology , vol.14 , pp. 19-41
    • Fuxe, K.1    Andersson, K.2    Eneroth, P.3    Harfstrand, A.4    Agnati, L.5
  • 46
    • 0028106622 scopus 로고
    • Effects of smoking and nicotine on the gastric mucosa: A review of clinical and experimental evidence
    • Endoh K, Leung FW. Effects of smoking and nicotine on the gastric mucosa: a review of clinical and experimental evidence. Gastroenterology 1994;107:864-78.
    • (1994) Gastroenterology , vol.107 , pp. 864-878
    • Endoh, K.1    Leung, F.W.2
  • 47
    • 0031404913 scopus 로고    scopus 로고
    • Is smoking still important in the pathogenesis of peptic ulcer disease?
    • Eastwood GL. Is smoking still important in the pathogenesis of peptic ulcer disease? J Clin Gastroenterol 1997;25(Suppl 1):S1-S7.
    • (1997) J Clin Gastroenterol , vol.25 , Issue.SUPPL. 1
    • Eastwood, G.L.1
  • 49
    • 0027257240 scopus 로고
    • The nicotine content of common vegetables
    • Domino EF, Hornbach E, Demana T. The nicotine content of common vegetables. N Engl J Med 1993;329:437-43.
    • (1993) N Engl J Med , vol.329 , pp. 437-443
    • Domino, E.F.1    Hornbach, E.2    Demana, T.3
  • 50
    • 0002699853 scopus 로고
    • Dietary nicotine and its significance in studies on tobacco smoking
    • Castro A, Monji N. Dietary nicotine and its significance in studies on tobacco smoking. Biochem Arch 1986;2:91-7.
    • (1986) Biochem Arch , vol.2 , pp. 91-97
    • Castro, A.1    Monji, N.2
  • 51
    • 84985275158 scopus 로고
    • Detection of nicotine in foods and plant materials
    • Sheen SJ. Detection of nicotine in foods and plant materials. J Food Sci 1988;53:1572-3.
    • (1988) J Food Sci , vol.53 , pp. 1572-1573
    • Sheen, S.J.1
  • 52
    • 0025277692 scopus 로고
    • A personal monitoring study to assess workplace exposure to environmental tobacco smoke
    • Coultas DB, Samet JM, McCarthy JF, Spengler JD. A personal monitoring study to assess workplace exposure to environmental tobacco smoke. Am J Public Health 1990;80:988-90.
    • (1990) Am J Public Health , vol.80 , pp. 988-990
    • Coultas, D.B.1    Samet, J.M.2    McCarthy, J.F.3    Spengler, J.D.4
  • 54
    • 0031888039 scopus 로고    scopus 로고
    • Exposure of casino employees to environmental tobacco smoke
    • Trout D, Decker J, Mueller C, Bernert JT, Pirkle J. Exposure of casino employees to environmental tobacco smoke. JOEM 1998;40:270-6.
    • (1998) JOEM , vol.40 , pp. 270-276
    • Trout, D.1    Decker, J.2    Mueller, C.3    Bernert, J.T.4    Pirkle, J.5
  • 55
    • 0033028068 scopus 로고    scopus 로고
    • Markers of environmental tobacco smoke exposure
    • Benowitz NL. Markers of environmental tobacco smoke exposure. Environ Health Perspect 1999;107(Supp 2):349-55.
    • (1999) Environ Health Perspect , vol.107 , Issue.SUPPL. 2 , pp. 349-355
    • Benowitz, N.L.1
  • 57
    • 29044432972 scopus 로고    scopus 로고
    • Pravilnik o maksimalno dopustivim koncentracijama štetnih tvari u atmosferi radnih prostorija i prostora i o biološkim graničnim vrijednostima
    • 92/1993
    • Pravilnik o maksimalno dopustivim koncentracijama štetnih tvari u atmosferi radnih prostorija i prostora i o biološkim graničnim vrijednostima. Narodne novine 92/1993.
    • Narodne Novine


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.