Maternal treatment with a high dose of CpG ODN during gestation alters fetal craniofacial and distal limb development in C57BL/6 mice

Vaccine

Volumn 24, Issue 3, 2006, Pages 263-271

  Prater, M Renee ^a,b   Johnson, Victor J ^c   Germolec, Dori R ^d   Luster, Michael I ^c   Holladay, Steven D ^b  

^a EDWARD VIA COLLEGE OF OSTEOPATHIC MEDICINE   (United States)

^b VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^c NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Abortion; CpG ODN; Craniofacial and distal limb development; Fetal malformation; Immunostimulatory DNA; Th1 cytokine shift

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIFICATION; CELL DEATH; CRANIOFACIAL DEVELOPMENT; CRANIOFACIAL MALFORMATION; DRUG MEGADOSE; FEMALE; FETUS; FETUS RESORPTION; HISTOLOGY; HYPOTHESIS; INFLAMMATION; INJECTION; INNER EAR DISEASE; LIMB DEFECT; LIMB DEVELOPMENT; MALE; NONHUMAN; PLACENTA; PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TREATMENT OUTCOME; TROPHOBLAST;

ANIMALS; BODY WEIGHT; CPG ISLANDS; CRANIOFACIAL ABNORMALITIES; CYTOKINES; DNA, BACTERIAL; FEMALE; FETAL DEATH; FETAL RESORPTION; FETAL WEIGHT; LIMB DEFORMITIES, CONGENITAL; MALE; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDES; PLACENTA; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY, ANIMAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; VACCINES, DNA;

EID: 29044438533     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2005.07.105     Document Type: Article

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