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The error in these values is ± 0.10, which is the error in measuring pH
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The error in these values is ± 0.10, which is the error in measuring pH.
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36
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33847452526
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note
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A second vibrational mode was present in the amide I region of a 0.10 M solution of 2 in dioxane. This low frequency mode was absent in a 1.0 mM solution of 2. This second vibrational mode was likely the result of a hydrogen bond from the hydroxyl group of one molecule of 2 to the amide carbonyl group of another molecule of 2, as was observed in crystalline 2 (ref. 29). To minimize this apparent aggregation, FTIR experiments in dioxane were performed on 1.0 mM solutions of 1-3.
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37
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33847456135
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note
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A kinetic analysis of 2 in dioxane was precluded by aggregation. Decreasing the concentration of 2 from 0.10 M to 1.0 mM resulted in a 10-20% increase in isomerization rates and an increase in error from < 10% to >60%, depending on the temperature. The aggregation of 2 in dioxane during NMR spectroscopy experiments was also observed by FTIR spectroscopy (ref 36).
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48
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33847471727
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note
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19F resonances at most temperatures.
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50
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