Enantio selective and gender-dependent depletion of chlordane compounds from rat tissues

Journal of Toxicology and Environmental Health - Part A

Volumn 68, Issue 22, 2005, Pages 1917-1938

  Bondy, Genevieve S ^a   Coady, Laurie ^a   Doucet, Josée ^a   Armstrong, Cheryl ^a   Kriz, Robert ^a   Liston, Virginia ^a   Robertson, Patrick ^b   Norstrom, Ross ^c   Moisey, John ^c  

^a TOXICOLOGY RESEARCH DIVISION   (Canada)

^b Health Canada and World Health Organization Collaborating Center for Standardization and Evaluation of Biologicals   (Canada)

^c ENVIRONMENT CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORDANE; MICROSOME ENZYME; NONACHLOR; OXYCHLORDANE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BODY BURDEN; CHIRALITY; COMPARATIVE STUDY; CONTROLLED STUDY; DEPLETION; ENANTIOMER; ENANTIOSELECTIVITY; ENZYME INDUCTION; FEMALE; FOOD CONTAMINATION; LIVER WEIGHT; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; TISSUE DISTRIBUTION; TOXICOKINETICS; TOXICOLOGICAL PARAMETERS; TOXIN ANALYSIS;

ANIMALIA; RODENTIA;

EID: 28844476780     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390500226920     Document Type: Article

References (33)

1. Addison, R. F., and Smith, T. G. 1998. Trends in organochlorine residue concentrations in ringed seal (Phoca hispida) from Holman, Northwest Territories, 1972-91. Arctic 51:253-261.
2. Arctic Monitoring and Assessment Programme 2004 AMAP assessment 2002: Persistent organic pollutants (POPs) in the Arctic. Oslo, Norway: AMAP.
3. Barnett, J. R., and Dorough, H. W. 1974. Metabolism of chlordane in rats. J. Agric. Food Chem. 22:612-619.
4. Bondy, G. S., Newsome, W. H., Armstrong, C. L., Suzuki, C. A. M., Doucet, J., Fernie, S., Hierlihy, S. L., Feeley, M. M., and Barker, M. G. 2000. trans-Nonachlor and cis-nonachlor toxicity in Sprague-Dawley rats: Comparison with technical chlordane. Toxicol. Sci. 58:386-398.
5. Bondy, G., Armstrong, C., Coady, L., Doucet, J., Robertson, P., Feeley, M., and Barker, M. 2003. Toxicity of the chlordane metabolite oxychlordane in female rats: clinical and histopathological changes. Food Chem. Toxicol. 41:291-301.
6. Bondy, G., Curran, I., Doucet, J., Armstrong, C., Coady, L., Hierlihy, L., Fernie, S., Robertson, P., and Barker, M. 2004. Toxicity of trans-nonachlor to Sprague-Dawley rats in a 90-day feeding study. Food Chem. Toxicol. 42:1015-1027.
7. Campbell, M. A., Gyorkos, J., Leece, B., Homonko, K, and Safe, S. 1983. The effects of twenty-two organochlorine pesticides as inducers of the hepatic drug-metabolizing enzymes. Gen. Pharmacol. 14:445-454.
8. Dearth, M. A., and Hites, R. A. 1991a. Complete analysis of technical chlordane using negative ionization mass spectrometry. Environ. Sci. Technol. 25:245-254.
9. Dearth, M. A., and Hites, R. A. 1991b. Depuration rates of chlordane compounds from rat fat. Environ. Sci. Technol. 25:1125-1128.
10. Esterbauer, H., and Cheeseman, K. H. 1990. Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal. Methods Enzymol 186:407-421.
11. Fisk, A. T., Moisey, J., Hobson, K. A., Karnovsky, N. J., and Norstrom, R. J. 2001. Chlordane components and metabolites in seven species of Arctic seabirds from the Northwater Polynya: Relationships with stable isotopes of nitrogen and enantiomeric fractions of chiral components. Environ. Pollut. 113:225-238.
12. Fisk, A. T., Holst, M., Hobson, K. A., Diffe, J., Moisey, J., and Norstrom, R. J. 2002. Persistent organochlorine contaminants and enantiomeric signatures of chiral pollutants in ringed seals (Phoca hispada) collected on the east and west side of the Northwater Polynya, Canadian Arctic. Arch. Environ. Contam. Toxicol. 42:118-126.
13. Gornall, A. G., Bardawill, C. J., and David, M. M. 1949. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177:751-766.
14. Hegeman, W. J. M., and Laane, R. W. P. M. 2002. Enantiomeric enrichment of chiral pesticides in the environment. Rev. Environ. Contam. Toxicol. 173:85-116.
15. Hoekstra, P. F., O'Hara, T. M., Karlsson, H., Soloman, K. R., and Muir, D. C. G. 2003. Enantiomer-specific biomagnification of α- hexachlorocyclohexane and selected chiral chlordane-related compounds within an Arctic marine food web. Environ. Toxicol. Chem. 22:2482-2491.
16. Hu, Y., and Kupfer, D. 2002. Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): Major differences in selective enantiomer formation by various P450 isoforms. Drug Metab. Dispos. 30:1329-1336.
17. Iwata, H., Tanabe, S., Iida, T., Baba, N., Ludwig, J. P., and Tatsukawa, R. 1998. Enantioselective accumulation of α-hexachlorocyclohexane in northern fur seals and double-crested cormorants: Effects of biological and ecological factors in the higher trophic levels. Environ. Sci. Technol. 32:2244-2249.
18. Karlsson, H., Oehme, M., Skopp, S., and Burkow, I. C. 2000. Enantiomer ratios of chlordane congeners are gender specific in cod (Gadus morhua) from the Barents Sea. Environ. Sci. Technol. 34:2126-2130.
19. Klobes, U., Vetter, W., Luckas, B., Skírnisson, K., and Plötz, J. 1998. Levels and enantiomeric ratios of α-HCH, oxychlordane, and PCB 149 in blubber of harbour seals (Phoca vitulina) and grey seals (Halichoerus gryphus) from Iceland and further species. Chemosphere 37:2501-2512.
20. Kuhnlein, H. V. 1995. Benefits and risks of traditional food for Indigenous peoples: Focus on dietary intakes of Arctic men. Can. J. Physiol. Pharmacol. 73:765-771.
21. Miyazaki, A., Sakai, M., and Marumo, S. 1980. Synthesis and biological activity of optically active heptachlor, 2-chloroheptachlor, and 3-chloroheptachlor. J. Agric. Food Chem. 28:1310-1311.
22. Muir, D. C. G., Born, H. W., Koczansky, K., and Stern, G. A. 2000. Temporal and spatial trends of persistent organochlorines in Greenland walrus (O dobenus rosmarus romanis). Sci. Total Environ. 245:73-86.
23. Newsome, W. H., and Ryan, J. J. 1999. Toxaphene and other chlorinated compounds in human milk from northern and southern Canada: A comparison. Chemosphere 39:519-526.
24. Nims, R. W., and Lubet, R. A. 1995. Induction of cytochrome P-450 in the Norway rat, Rattus norvegicus, following exposure to potential environmental contaminants. J. Toxicol. Environ. Health. 46:271-292.
25. Ohno, Y., Kawanishi, T., Takahashi, A., Nakaura, S., Kawashima, K., Tanaka, S., Takanaka, A., Omori, Y., Sekita, H., and Uchiyama, M. 1986. Comparisons of the toxicokinetic parameters in rats determined for low dose and high dose of γ-chlordane. J. Toxicol. Sci. 11:111-123.
26. Polischuk, S. C., Norstrom, R. J., and Ramsay, M. A. 2002. Body burdens and tissue concentrations of organochlorines in polar bears (Ursus maritimus) vary during seasonal fasts. Environ. Pollut. 118:29-39.
27. Street, J. C., and Blau, S. E. 1972. Oxychlordane: Accumulation in rat adipose tissue on feeding chlordane isomers or technical chlordane. J. Agric. Food Chem. 20:395-397.
28. 1 on several markers of nephrotoxicity in rats. Toxicol. Appl. Pharmacol. 133:207-214.
29. Tashiro, S., and Matsumura, F. 1978. Metabolism of trans-nonachlor and related chlordane components in rat and man. Arch. Environ. Contam. 7:113-127.
30. Van Oostdam, J., Donaldson, S., Feeley, M., Tremblay N. eds. 2003 Toxic substances in the Arctic and associated affects - Human health. In Canadian Arctic contaminants assessment report II, pp. 14-16. Ottawa, Ontario, Canada: Indian and Northern Affairs Canada.
31. White, J. C., Mattina, M. J. I., Eitzer, B. D., and Iannuci-Berger, W. 2002. Tracking chlordane compositional and chiral profiles in soil and vegetation. Chemosphere 47:639-646.
32. Wiberg, K., Letcher, R. J., Sandau, C. D., Norstrom, R. J., Tyskind, M., and Bidleman, T. F. 2000. The enantioselective bioaccumulation of chiral chlordane and α-HCH contaminants in the polar bear food chain. Environ. Sci. Technol. 34:2668-2674.
33. Wong, C. S., Lau, F., Clark, M., Mabury, S. A., and Muir, D. C. G. 2002. Rainbow trout (Oncorhynchus mykiss) can eliminate chiral organochlorine compounds enantioselectively. Environ. Sci. Technol. 36:1267-1262.