Enantioselective metabolism of the endocrine disruptor pesticide methoxychlor by human cytochromes P450 (P450s): Major differences in selective enantiomer formation by various P450 isoforms

Drug Metabolism and Disposition

Volumn 30, Issue 12, 2002, Pages 1329-1336

  Hu, Yiding ^a   Kupfer, David ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; METHOXYCHLOR; PESTICIDE; INSECTICIDE; ISOENZYME;

ARTICLE; CATALYSIS; CHIRALITY; CONTROLLED STUDY; DEMETHYLATION; DRUG METABOLISM; ENANTIOMER; ESTROGEN ACTIVITY; HUMAN; HUMAN CELL; HYDROXYLATION; PRIORITY JOURNAL; RACEMIC MIXTURE; STEREOCHEMISTRY; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; ENDOCRINE SYSTEM; ENZYMOLOGY; LIVER MICROSOME; METABOLISM; STEREOISOMERISM;

MAMMALIA;

CYTOCHROME P-450 ENZYME SYSTEM; ENDOCRINE SYSTEM; HUMANS; INSECTICIDES; ISOENZYMES; METHOXYCHLOR; MICROSOMES, LIVER; STEREOISOMERISM;

EID: 0036892632     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.12.1329     Document Type: Article

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