Reversal of gene expression profile in the phenylketonuria mouse model after adeno-associated virus vector-mediated gene therapy

Molecular Genetics and Metabolism

Volumn 86, Issue SUPPL., 2005, Pages 124-132

  Oh, Hyun Jeong ^a,b   Lee, Hyejin ^a   Park, Joo Won ^c   Rhee, Hwanseok ^d   Koo, Soo Kyung ^a   Kang, Seongman ^b   Jo, Inho ^a   Jung, Sung Chul ^c  

^a Korea National Institute of Health   (South Korea)

^b Korea University   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

^d Yonsei University   (South Korea)

Author keywords

Adeno associated virus; Gene therapy; Microarray; Mouse; Neurological pathogenesis; Phenylketonuria

Indexed keywords

ADENOVIRUS VECTOR; BONE GAMMA CARBOXYGLUTAMATE PROTEIN RELATED SEQUENCE 1; CATHELIN RELATED ANTIMICROBIAL PEPTIDE; CD79A ANTIGEN; COLLAGENASE 3; LEUKOCYTE ELASTASE; LYSOZYME; MYELOPEROXIDASE; NEUTROPHILIC GRANULE PROTEIN; PHENYLALANINE 4 MONOOXYGENASE; PROCOLLAGEN I ALPHA1; PROCOLLAGEN I ALPHA2; PROTEIN; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

AMINO ACID BLOOD LEVEL; AMINO ACID BRAIN LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; CONTROLLED STUDY; DEGRADATION; DISEASE MODEL; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE STRUCTURE; GENE THERAPY; INFLAMMATION; MALE; MOUSE; NEUTROPHIL; NOCICEPTIVE RECEPTOR; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENYLKETONURIA; PRIORITY JOURNAL; PROTEIN FAMILY; SENSORY NERVE CELL; UPREGULATION; VIRAL GENE DELIVERY SYSTEM;

ADENO-ASSOCIATED VIRUS; ADENOVIRIDAE; ANIMALIA;

EID: 28844474908     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2005.06.015     Document Type: Article

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