Design, synthesis, and antifungal activity of inhibitors of brassilexin detoxification in the plant pathogenic fungus Leptosphaeria maculans

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 3, 2006, Pages 714-723

  Pedras, M Soledade C ^a   Suchy, Mojmir ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Brassilexin; Detoxification inhibitor; Leptosphaeria maculans; Phoma lingam; Phytoalexin

Indexed keywords

1,2 BENZOISOTHIAZOLE; 3 PHENYLTHIOPHENE; 4 (1 NAPHTHYL)ISOTHIAZOLE; 4 (2 AMINOPHENYL)ISOTHIAZOLE; 4 (2 CHLOROPHENYL)ISOTHIAZOLE; 4 (2 HYDROXYPHENYL)ISOTHIAZOLE; 4 (2 METHOXYPHENYL)ISOTHIAZOLE; 4 (2 NAPHTHYL)ISOTHIAZOLE; 4 (2 NITROPHENYL)ISOTHIAZOLE; 4 (2 TOLYL)ISOTHIAZOLE; 4 PHENYLISOTHIAZOLE; ANTIFUNGAL AGENT; BRASSILEXIN; INDOLE DERIVATIVE; ISOTHIAZOLE DERIVATIVE; ISOTHIAZOLO[5,4 B]QUINOLINE; ISOTHIAZOLO[5,4 B]THIANAPHTHENE; THIENO[2,3 B]INDOLE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL STRUCTURE; DETOXIFICATION; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; FUNGUS; FUNGUS CULTURE; GROWTH INHIBITION; INFRARED SPECTROSCOPY; LEPTOSPHAERIA MACULANS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTIFUNGAL AGENTS; ASCOMYCOTA; BIOLOGICAL ASSAY; BIOTRANSFORMATION; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; INDOLES; KINETICS; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANTS; TERPENES; THIAZOLES;

FUNGI; LEPTOSPHAERIA MACULANS;

EID: 28844470380     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.08.053     Document Type: Article

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