Biphenylsulfonacetic acid inhibitors of the human papillomavirus type 6 E1 helicase inhibit ATP hydrolysis by an allosteric mechanism involving tyrosine 486

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 12, 2005, Pages 4834-4842

  White, Peter W ^a   Faucher, Anne Marie ^a   Massariol, Marie Josée ^a   Welchner, Ewald ^a   Rancourt, Jean ^a   Cartier, Mireille ^a   Archambault, Jacques ^a,b  

^a BOEHRINGER INGELHEIM CANADA LTD   (Canada)

^b CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ANTIVIRUS AGENT; BIPHENYLSULFONACETIC ACID INHIBITOR; CYSTEINE; GLYCOPROTEIN E1; HELICASE; TYROSINE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ALLOSTERISM; ARTICLE; DNA REPLICATION; DRUG POTENCY; ENZYME ACTIVITY; EPITHELIUM; HUMAN PAPILLOMAVIRUS TYPE 6; IC 50; MUTAGENESIS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; VIRUS INFECTION; VIRUS INHIBITION; VIRUS REPLICATION;

ACETIC ACIDS; ADENOSINE TRIPHOSPHATE; ALLOSTERIC REGULATION; BIPHENYL COMPOUNDS; ENZYME INHIBITORS; HUMANS; HYDROLYSIS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRIDAE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; TYROSINE;

EID: 28844467115     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.12.4834-4842.2005     Document Type: Article

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