99mTc-labeling of colchicine using [99mTc(CO) 3(H2O)3]+ and [ 99mTc≡N]2+ core for the preparation of potential tumor-targeting agents

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 3, 2006, Pages 793-799

  Korde, Aruna ^a   Satpati, Drishty ^a   Mathur, Anupam ^a   Mallia, Madhava ^a   Banerjee, Sharmila ^a   Kothari, Kanchan ^a   Sarma, H D ^a   Choudhari, Pradeep ^a   Venkatesh, Meera ^a  

^a BHABHA ATOMIC RESEARCH CENTRE   (India)

Author keywords

99mTc N 2+; 99mTc(CO)3(H2O) 3 +; Colchicine; Dithiocarbamate; Iminodiacetic acid; Tumor

Indexed keywords

CARBONYL DERIVATIVE; COLCHICINE DERIVATIVE; DIGLYCINE DERIVATIVE TC 99M; DITHIOCARBAMIC ACID DERIVATIVE; TRIMETHYLCOLCHINIC ACID; UNCLASSIFIED DRUG; COLCHICINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER MODEL; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BINDING; DRUG DISTRIBUTION; DRUG LIVER LEVEL; DRUG SYNTHESIS; DRUG TARGETING; DRUG UPTAKE; FIBROSARCOMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; MOUSE; NONHUMAN; PRECURSOR; THIN LAYER CHROMATOGRAPHY; ANIMAL; CHEMISTRY; DRUG RESISTANCE; EXPERIMENTAL MELANOMA; EXPERIMENTAL NEOPLASM; MULTIDRUG RESISTANCE; SCINTISCANNING; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALIA; MINK CELL FOCUS-FORMING VIRUS;

ANIMALS; CELL LINE, TUMOR; COLCHICINE; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FIBROSARCOMA; MELANOMA, EXPERIMENTAL; MICE; NEOPLASMS, EXPERIMENTAL; ORGANOTECHNETIUM COMPOUNDS; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 28844449330     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.09.006     Document Type: Article

References (14)

1. T. Graening, and H.G. Schmalz Angew. Chem., Int. Ed. 43 2004 3230
2. N.H. Hendrikse, E.J.F. Franssen, W.T.A. Van der Graaf, W. Vaalburg, and E.G.E. de vries Eur. J. Nucl. Med. 26 1999 283
3. A. Levchenko, B.M. Mehta, J.B. Lee, J.L. Humm, F. Augensen, O. Squire, P.J. Kothari, R.D. Finn, E.F. Leonard, and S.M. Larson J. Nucl. Med. 41 2000 493
4. J.F. Zareneyrizi, D.J. Yang, C.S. Oh, S. Ilgan, D.F. Yu, W. Tansey, C.W. Liu, E.E. Kim, and D.A. Podoloff Anticancer Drugs 10 1999 685
5. S. Jurrison, and J.D. Lydon Chem. Rev. 1999 2205
6. S. Banerjee, M.R.A. Pillai, and N. Ramamoorthy Semin. Nucl. Med. 32 2001 260
7. R. Alberto, R. Schibli, A. Egli, A.P. Schubiger, U. Abram, and T.A. Kaden J. Am. Chem. Soc. 120 1998 7987
8. A. Egli, R. Alberto, L. Tannahill, R. Schibli, U. Abram, and A. Schaffland J. Nucl. Med. 40 1999 1913
9. R. Waibel, R. Alberto, J. Willuda, R. Finnern, R. Schibli, and A. Stichelberger Nat. Biotechnol. 17 1999 897
10. C. Bolzati, A. Boschi, L. Uccelli, E. Malago, G. Bandoli, F. Tisato, F. Refosco, R. Pasqualini, and A. Duatti Inorg. Chem. 38 1999 4473
11. R. Pasqualini, V. Comazzi, E. Bellande, A. Duatti, and A. Marchi Int. J. Appl. Radiat. Isot. 43 1992 1329
12. J.P. Kothari, D.R. Finn, and M.S. Larson J. Label Compd. Radiopharmaceut. 36 1994 521
13. J.M. Elliot, J.R. Chipperfield, and S. Clark Inorg. Chem. 41 2002 293
14. S. Abram, A. Abram, H. Spies, and R. Munze J. Radioanal. Nucl. Ch. Ar. 102 1986 309