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Volumn 131, Issue 6, 2005, Pages 759-768

Construction and characterization of recombinant single-chain variable fragment antibodies against Toxoplasma gondii MIC2 protein

Author keywords

Monoclonal antibodies; Phage display; Recombinant protein; Toxoplasmosis

Indexed keywords

MONOCLONAL ANTIBODY; PARASITE ANTIGEN; PROTEIN ANTIBODY; PROTEIN MIC2; PROTOZOAL PROTEIN; RECOMBINANT ANTIBODY; RECOMBINANT PROTEIN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

EID: 28844432623     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182005008450     Document Type: Article
Times cited : (11)

References (36)
  • 1
    • 2942550031 scopus 로고    scopus 로고
    • Generation of antibody libraries: PCR amplification and assembly of light-and heavy-chain coding sequences
    • ed. Barbas, C. F., Burton, D. R., Scott, J. K. and Silverman, G. J., Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Andris-Widhopf, J., Steinberger, P., Fuller, R., Rader, C. and Barbas, C. F. (2001). Generation of antibody libraries: PCR amplification and assembly of light-and heavy-chain coding sequences. In Phage Display: A Laboratory Manual (ed. Barbas, C. F., Burton, D. R., Scott, J. K. and Silverman, G. J.), pp. 9.1-9.113. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
    • (2001) Phage Display: A Laboratory Manual
    • Andris-Widhopf, J.1    Steinberger, P.2    Fuller, R.3    Rader, C.4    Barbas, C.F.5
  • 2
    • 0032535999 scopus 로고    scopus 로고
    • Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
    • Arap, W., Pasqualini, R. and Ruoslahti, E. (1998). Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279, 377-380.
    • (1998) Science , vol.279 , pp. 377-380
    • Arap, W.1    Pasqualini, R.2    Ruoslahti, E.3
  • 4
    • 13444305223 scopus 로고    scopus 로고
    • A combination of antigenic regions of Toxoplasma gondii microneme proteins induces protective immunity against oral infection with parasite cysts
    • Beghetto, E., Nielsen, H. V., Del Porto, P., Buffolano, W., Guglietta, S., Felici, F., Petersen, E. and Gargano, N. (2005). A combination of antigenic regions of Toxoplasma gondii microneme proteins induces protective immunity against oral infection with parasite cysts. Journal of Infectious Diseases 191, 637-645.
    • (2005) Journal of Infectious Diseases , vol.191 , pp. 637-645
    • Beghetto, E.1    Nielsen, H.V.2    Del Porto, P.3    Buffolano, W.4    Guglietta, S.5    Felici, F.6    Petersen, E.7    Gargano, N.8
  • 5
    • 0031813707 scopus 로고    scopus 로고
    • Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein
    • Bera, T. K., Kennedy, P. E., Berger, E. A., Barbas, C. F. III and Pastan, I. (1998). Specific killing of HIV-infected lymphocytes by a recombinant immunotoxin directed against the HIV-1 envelope glycoprotein. Molecular Medicine 4, 384-391.
    • (1998) Molecular Medicine , vol.4 , pp. 384-391
    • Bera, T.K.1    Kennedy, P.E.2    Berger, E.A.3    Barbas III, C.F.4    Pastan, I.5
  • 6
    • 28844477359 scopus 로고    scopus 로고
    • Antibody libraries
    • ed. Barbas, C. F., Burton, D. R., Scott, J. K. & Silverman, G. J., Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Burton, D. R. (2001). Antibody libraries. In Phage Display: A Laboratory Manual (ed. Barbas, C. F., Burton, D. R., Scott, J. K. & Silverman, G. J.), pp. 3.1-3.18. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
    • (2001) Phage Display: A Laboratory Manual
    • Burton, D.R.1
  • 7
    • 0036155839 scopus 로고    scopus 로고
    • Host cell invasion by the opportunistic pathogen Toxoplasma gondii
    • Carruthers, V. B. (2002) Host cell invasion by the opportunistic pathogen Toxoplasma gondii. Acta Tropica 81, 111-122.
    • (2002) Acta Tropica , vol.81 , pp. 111-122
    • Carruthers, V.B.1
  • 8
    • 0030956863 scopus 로고    scopus 로고
    • Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts
    • Carruthers, V. B. and Sibley, L. D. (1997). Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts. European Journal of Cellular Biology 73, 114-123.
    • (1997) European Journal of Cellular Biology , vol.73 , pp. 114-123
    • Carruthers, V.B.1    Sibley, L.D.2
  • 9
  • 10
    • 0033056238 scopus 로고    scopus 로고
    • Improving antibody affinity by mimicking somatic hypermutation in vitro
    • Chowdhury, P. S. and Pastan, I. (1999). Improving antibody affinity by mimicking somatic hypermutation in vitro. Nature Biotechnology 17, 568-572.
    • (1999) Nature Biotechnology , vol.17 , pp. 568-572
    • Chowdhury, P.S.1    Pastan, I.2
  • 11
    • 0033922059 scopus 로고    scopus 로고
    • Optimizing the expression of a monoclonal antibody fragment under the transcriptional control of the Escherichia coli lac promoter
    • Donovan, R. S., Robinson, C. W. and Glick, B. R. (2000). Optimizing the expression of a monoclonal antibody fragment under the transcriptional control of the Escherichia coli lac promoter. Canadian Journal of Microbiology 46, 532-541.
    • (2000) Canadian Journal of Microbiology , vol.46 , pp. 532-541
    • Donovan, R.S.1    Robinson, C.W.2    Glick, B.R.3
  • 13
    • 18244400631 scopus 로고    scopus 로고
    • Production and purification of Fab and scFv
    • ed. Barbas, C. F., Burton, D. R., Scott, J. K. & Silverman, G. J., Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Elia, M., Andris-Widhopf, J., Fuller, R. and Barbas, C. F. (2001). Production and purification of Fab and scFv. In Phage Display: A Laboratory Manual (ed. Barbas, C. F., Burton, D. R., Scott, J. K. & Silverman, G. J.), pp. 12.1-12.26. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
    • (2001) Phage Display: A Laboratory Manual
    • Elia, M.1    Andris-Widhopf, J.2    Fuller, R.3    Barbas, C.F.4
  • 15
    • 0003448569 scopus 로고
    • Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
    • Harlow, E. and Lane, D. (1988). Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
    • (1988) Antibodies: A Laboratory Manual
    • Harlow, E.1    Lane, D.2
  • 16
    • 1542375192 scopus 로고    scopus 로고
    • Multimerization of the Toxoplasma gondii MIC2 integrin-like A-domain is required for binding to heparin and human cells
    • Harper, J. M., Hoff, E. F. and Carruthers, V. B. (2004). Multimerization of the Toxoplasma gondii MIC2 integrin-like A-domain is required for binding to heparin and human cells. Molecular and Biochemical Parasitology 134, 201-212.
    • (2004) Molecular and Biochemical Parasitology , vol.134 , pp. 201-212
    • Harper, J.M.1    Hoff, E.F.2    Carruthers, V.B.3
  • 17
    • 0027768856 scopus 로고
    • The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme
    • Hawkins, R. E., Russell, S. J., Baier, M. and Winter, G. (1993). The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme. Journal of Molecular Biology 234, 958-964.
    • (1993) Journal of Molecular Biology , vol.234 , pp. 958-964
    • Hawkins, R.E.1    Russell, S.J.2    Baier, M.3    Winter, G.4
  • 20
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970). Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature, London 227, 680.
    • (1970) Nature, London , vol.227 , pp. 680
    • Laemmli, U.K.1
  • 21
    • 0032801102 scopus 로고    scopus 로고
    • Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: Effect of valency on cell binding
    • Le Gall, F., Kipriyanov, S. M., Moldenhauer, G. and Little, M. (1999). Di-, tri- and tetrameric single chain Fv antibody fragments against human CD19: effect of valency on cell binding. FEBS Letters 453, 164-168.
    • (1999) FEBS Letters , vol.453 , pp. 164-168
    • Le Gall, F.1    Kipriyanov, S.M.2    Moldenhauer, G.3    Little, M.4
  • 22
    • 0005229135 scopus 로고    scopus 로고
    • Mimicking somatic hypermutation: Affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain
    • Low, N. M., Holliger, P. and Winter, G. (1996). Mimicking somatic hypermutation: affinity maturation of antibodies displayed on bacteriophage using a bacterial mutator strain. Journal of Molecular Biology 260, 359-368.
    • (1996) Journal of Molecular Biology , vol.260 , pp. 359-368
    • Low, N.M.1    Holliger, P.2    Winter, G.3
  • 23
    • 0344196823 scopus 로고    scopus 로고
    • A new epitope tag from Hepatitis B virus preS1 for immunodetection, localization and affinity purification of recombinant proteins
    • Oh, M. S., Kim, K. S., Jang, Y. K., Maeng, C. Y., Min, S. H., Jang, M. H., Yoon, S. O., Kim, J. H. and Hong, H. J. (2003). A new epitope tag from Hepatitis B virus preS1 for immunodetection, localization and affinity purification of recombinant proteins. Journal of Immunological Methods 283, 77-89.
    • (2003) Journal of Immunological Methods , vol.283 , pp. 77-89
    • Oh, M.S.1    Kim, K.S.2    Jang, Y.K.3    Maeng, C.Y.4    Min, S.H.5    Jang, M.H.6    Yoon, S.O.7    Kim, J.H.8    Hong, H.J.9
  • 24
    • 0034177534 scopus 로고    scopus 로고
    • T cell clones raised from chronically infected healthy humans by stimulation with Toxoplasma gondii excretory-secretory antigens cross-react with live tachyzoites: Characterization of the fine antigenic specificity of the clones and implications for vaccine development
    • Prigione, I., Facchetti, P., Lecordier, L., Deslee, D., Chiesa, S., Cesbron-Delauw, M. F. and Pistoia, V. (2000). T cell clones raised from chronically infected healthy humans by stimulation with Toxoplasma gondii excretory-secretory antigens cross-react with live tachyzoites: characterization of the fine antigenic specificity of the clones and implications for vaccine development. Journal of Immunology 164, 3741-3748.
    • (2000) Journal of Immunology , vol.164 , pp. 3741-3748
    • Prigione, I.1    Facchetti, P.2    Lecordier, L.3    Deslee, D.4    Chiesa, S.5    Cesbron-Delauw, M.F.6    Pistoia, V.7
  • 25
    • 0037124107 scopus 로고    scopus 로고
    • Selection and identification of dense granule antigen GRA3 by Toxoplasma gondii whole genome phage display
    • Robben, J., Hertveldt, K., Bosmans, E. and Volckaert, G. (2002). Selection and identification of dense granule antigen GRA3 by Toxoplasma gondii whole genome phage display. Journal of Biological Chemistry 277, 17544-17547.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 17544-17547
    • Robben, J.1    Hertveldt, K.2    Bosmans, E.3    Volckaert, G.4
  • 26
    • 0023741661 scopus 로고
    • A highly conserved amino acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite
    • Robson, K. J. H., Hall, J. R. S., Jennings, M. W., Harris, T. J. R., Marsh, K., Newbold, C. I., Tate, V. E. and Weatherall, D. J. (1988). A highly conserved amino acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite. Nature, London 335, 79-82.
    • (1988) Nature, London , vol.335 , pp. 79-82
    • Robson, K.J.H.1    Hall, J.R.S.2    Jennings, M.W.3    Harris, T.J.R.4    Marsh, K.5    Newbold, C.I.6    Tate, V.E.7    Weatherall, D.J.8
  • 29
    • 0021818675 scopus 로고
    • Filamentous fusion phage: Novel expression vectors that display cloned antigens on the surface of the virion
    • Smith, G. P. (1985). Filamentous fusion phage: novel expression vectors that display cloned antigens on the surface of the virion. Science 288, 1315-1317.
    • (1985) Science , vol.288 , pp. 1315-1317
    • Smith, G.P.1
  • 32
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
    • Towbin, H., Staehelin, T. and Gordon, J. (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proceedings of the National Academy of Sciences, USA 76, 4350.
    • (1979) Proceedings of the National Academy of Sciences, USA , vol.76 , pp. 4350
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 33
    • 0029617767 scopus 로고
    • Molecular cloning of a gene from Plasmodium falciparum that codes for a protein sharing motif found in adhesive molecules from mammals and Plasmodia
    • Trottein, F., Triglia, T. and Cowman, A. F. (1995). Molecular cloning of a gene from Plasmodium falciparum that codes for a protein sharing motif found in adhesive molecules from mammals and Plasmodia. Molecular and Biochemical Parasitology 74, 129-141.
    • (1995) Molecular and Biochemical Parasitology , vol.74 , pp. 129-141
    • Trottein, F.1    Triglia, T.2    Cowman, A.F.3
  • 34
    • 0029960911 scopus 로고    scopus 로고
    • Toxoplasma gondii expressed sequence tags: Insights into tachyzoite gene expression
    • Wan, K.-L., Blackwell, J. M. and Ajioka, J. W. (1996). Toxoplasma gondii expressed sequence tags: insights into tachyzoite gene expression. Molecular and Biochemical Parasitology 75, 179-186.
    • (1996) Molecular and Biochemical Parasitology , vol.75 , pp. 179-186
    • Wan, K.-L.1    Blackwell, J.M.2    Ajioka, J.W.3
  • 35
    • 0031044707 scopus 로고    scopus 로고
    • Molecular characterization of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2
    • Wan, K.-L., Carruthers, V. B., Sibley, L. D. and Ajioka, J. W. (1997). Molecular characterization of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2. Molecular and Biochemical Parasitology 84, 203-214.
    • (1997) Molecular and Biochemical Parasitology , vol.84 , pp. 203-214
    • Wan, K.-L.1    Carruthers, V.B.2    Sibley, L.D.3    Ajioka, J.W.4
  • 36
    • 0035951540 scopus 로고    scopus 로고
    • A single-chain variable region immunoglobulin library from the abomasal lymph node of sheep infected with the gastrointestinal nematode parasite Haemonchus contortus
    • White, G. P., Meeusen, E. N. and Newton, S. E. (2001). A single-chain variable region immunoglobulin library from the abomasal lymph node of sheep infected with the gastrointestinal nematode parasite Haemonchus contortus. Veterinary Immunology and Immunopathology, 78, 117-129.
    • (2001) Veterinary Immunology and Immunopathology , vol.78 , pp. 117-129
    • White, G.P.1    Meeusen, E.N.2    Newton, S.E.3


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