Teaching systems biology: An active-learning approach

Cell Biology Education

Volumn 4, Issue WINTER, 2005, Pages 323-329

  Kumar, Anuj ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Active learning; Bioinformatics; Cooperative learning; Functional genomics; Graduate; Systems biology; Undergraduate; Yeast

Indexed keywords

CONTROLLED STUDY; COOPERATION; DNA MICROARRAY; HUMAN; HYBRID; HYPOTHESIS; LEARNING; MEDICAL EDUCATION; REVIEW; SAMPLE; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; UNITED STATES; UNIVERSITY;

DATA COLLECTION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROBLEM-BASED LEARNING; SEQUENCE HOMOLOGY; STUDENTS; SYSTEMS BIOLOGY; TEACHING; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 28644442528     PISSN: 15367509     EISSN: 15367509     Source Type: Journal    
DOI: 10.1187/cbe.04-12-0057     Document Type: Review

References (25)

1. Altschul, S.F., Gish, W., Miller, W., Meyers, E.W., and Lipman, D.J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
2. Baines, A.T., McVey, M., Rybarczyk, B., Thompson, J.T., and Wilkins, H.R. (2004). Mystery of the toxic flea dip: an interactive approach to teaching aerobic cellular respiration. Cell Biol. Educ. 3, 62-68.
3. Boutros, M., Kiger, A.A., Armknecht, S., Kerr, K., Hild, M., Koch, B., Haas, S.A., Consortium, H.F., Paro, R., and Perrimon, N. (2004). Genome-wide RNAi analysis of growth and viability in Drosophila cells. Science 303, 832-835.
4. Campbell, A.M. (2003). Public access for teaching genomics, proteomics, and bioinformatics. Cell Biol. Educ. 2, 98-111.
5. Clarke, J. (1994). Pieces of the puzzle: the jigsaw method. In: Handbook of Cooperative Learning Methods, ed. S. Sharan. Westport, CT: Greenwood Press, 34-50.
6. Coelho, P.S., Kumar, A., and Snyder, M. (2000). Genome-wide mutant collections: toolboxes for functional genomics. Curr. Opin. Microbiol. 3, 309-315.
7. Davidson, E.H., Rast, J.P., Oliveri, P., Ransick, A., Calestani, C., Yuh, C.H., Minokawa, T., Amore, G., Hinman, V., Arenas-Mena, C., Otim, O., Brown, C.T., Livi, C.B., Lee, P.Y., Revilla, R., Rust, A.G., Pan, Z., Schilstra, M.J., Clarke, P.J., Arnone, M.I., Rowen, L., Cameron, R.A., McClay, D.R., Hood, L., and Bolouri, H. (2002). A genomic regulatory network for development. Science 295, 1669-1678.
8. DeRisi, J.L., Iyer, V.R., and Brown, P.O. (1997). Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278, 680-686.
9. Harwood, W.S. (2003). Course enhancement: a road map for devising active-learning and inquiry-based science courses. Int. J. Dev. Biol. 47, 213-221.
10. Ideker, T., Thorsson, V., Ranish, J.A., Christmas, R., Buhler, J., Eng, J.K., Bumgarner, R., Goodlett, D.R., Aebersold, R., and Hood, L. (2001). Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. Science 292, 929-934.
11. International Human Genome Sequencing Consortium (2004). Finishing the euchromatic sequence of the human genome. Nature 431, 931-945.
12. Kamath, R., Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta, M., Kanapin, A., Le Bot, N., Moreno, S., Sohrmann, M., Welchman, D.P., Zipperlen, P., and Ahringer, J. (2003). Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421, 231-237.
13. Kitano, H. (2002). Systems biology: a brief overview. Science 295, 1662-1664.
14. Klionsky, D.J. (2002). Constructing knowledge in the lecture hall: a quiz-based group-learning approach to introductory biology. J. Coll. Sci. Teach. 31, 246-251.
15. Koonin, E.V. (1997). Big time for small genomes. Genome Res. 7, 418-421.
16. Kumar, A., and Snyder, M. (2001). Emerging technologies in yeast genomics. Nat. Rev. Genet. 2, 302-312.
17. Lord, T.R. (1994). Using constructivism to enhance student learning in college biology. J. Coll. Sci. Teach. 23, 346-348.
18. Malacinski, G.M. (2003). Student-oriented learning: an inquiry-based developmental biology lecture course. Int. J. Dev. Biol. 47 135-140.
19. Malacinski, G.M., and Zell, P.W. (1996). Learning molecular biology means more than memorizing the formula for tryptophan. J. Coll. Sci. Teach. 25, 198-202.
20. McKinney, K., and Graham-Buxton, M. (1993). The use of collaborative learning groups in the large class: is it possible? Teach. Sociol. 21, 403-408.
21. Olsen, G.J., and Woese, C.R. (1997). Archaeal genomics: an overview. Cell 89, 991-994.
22. Paulson, D.R., and Faust, J.L. (2002). Active Learning for the College Classroom. http://www.calstatela.edu/dept/chem/chem2/Active/ index.htm (accessed 30 November, 2004).
23. Schena, M., Shalon, D., Davis, R.W., and Brown, P.O. (1995). Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270, 467-470.
24. Sharan, S. (1994). Handbook of Cooperative Learning Methods. Westport, CT: Greenwood Press.
25. Wyckoff, S. (2001). Changing the culture of undergraduate science teaching. J. Coll. Sci. Teach. 29, 409-414.