Autoantibody profiles in the sera of patients with Q fever: Characterization of antigens by immunofluorescence, immunoblot and sequence analysis

Journal of Autoimmune Diseases

Volumn 2, Issue , 2005, Pages

  Camacho, M T ^a   Outschoorn, I ^a   Tellez, A ^a   Sequi J ^b  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; AUTOANTIBODY; CELL ANTIGEN; CELL EXTRACT; CYTOSKELETON PROTEIN; ELONGATION FACTOR 1ALPHA; HEART ANTIBODY; SMOOTH MUSCLE ANTIBODY;

ADULT; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; CLINICAL RESEARCH; CONTROLLED STUDY; FEMALE; HELA CELL; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INCIDENCE; MALE; OBSERVATION; Q FEVER; SEQUENCE HOMOLOGY;

EID: 28644436937     PISSN: 17402557     EISSN: 17402557     Source Type: Journal    
DOI: 10.1186/1740-2557-2-10     Document Type: Article

References (45)

1. Madariaga MG, Rezai K, Trenholme GM, Weinstein RA: Q fever: a biological weapon in your backyard. Lancet Infect Dis 2003, 3(11):709-721.
2. Maurin M, Raoult D: Q Fever. Clin Microbiol Rev 1999, 12:518-553.
3. Harris RJ, Storm PA, Lloyd A, Arens M, Marmion BP: Long-term persistence of Coxiella burnetii in the host after primary Q fever. Epidemiol Infect 2000, 124:543-549.
4. Raoult D, Marrie TJ, Mege JL: Natural history and pathophysiology of Q fever. Lancet Infect Dis 2005, 5:219-226.
5. Arricau-Bouvery N, Rodolakis A: Is Q fever and emerging or reemerging zoonosis? Vet Res 2005, 36:327-349.
6. Raoult D, Tissot-Dupont H, Foucault C, Gouvernet J, Fournier PE, Bernit E, Stein A, Nesri M, Harle J, Weiller PJ: Q fever 1985-1998. Medicine 2000, 79:109-123.
7. Bossi P, Tegnell A, Baka A, van Loock F, Hendriks J, Werner A, Maidhof H, Gouvras G: Bichat Guidelines for the Clinical Management of Q Fever and Bioterrorism-Related Q Fever. Eurosurveillance 2004, 9(12E19-E20 [http://www.eurosurveillance.org].
8. Fournier PE, Marrie TJ, Raoult D: Diagnosis of Q fever. J Clin Microbiol 1998, 36:1823-1933.
9. Dighiero G, Rose NR: Critical self-epitopes are key to the understanding of self-tolerance and autoimmunity. Immunol Today 1999, 20:423-428.
10. Klareskog L, Lorentzen J, Padyukov L, Alfredsson L: Genes and environment in arthritis: can RA be prevented? Arthritis Res 2002, 4:31-36.
11. Kamradt T, Goggel R, Erg KJ: Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection. Trends Immunol 2005, 26:260-267.
12. Slev PR, Potts WK: Disease consequences of pathogen adaptation. Curr Opin Immunol 2002, 14:609-614.
13. Behar SM, Porcelli SA: Mechanisms of autoimmune disease induction. The role of the immune response to microbial pathogens. Arthritis Rheum 1995, 38:458-476.
14. Small PLC, Ramakrishnan L, Falkow S: Remodelling schemes of intracellular pathogens. Science 1994, 263:637-639.
15. Aichele P, Bachmann MF, Hengartner H, Zinkernagel RM: Immunopathology or organ-specific autoimmunity as a consequence of virus infection. Immunol Rev 1996, 152:21-45.
16. Naucler CS, Larsson S, Moller E: A novel mechanism for virus-induced autoimmunity in humans. Immunol Rev 1996, 152:175-192.
17. Von Herrath MG, Oldstone MBA: Virus-induced autoimmune disease. Curr Opin Immunol 1996, 8:878-885.
18. Kaplan D, Ferrari I, Lopez Bergami P, Mahler E, Levitus G, Chiale P, Hoebekes J, Van Regenmortel MHV, Levin MJ: Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus. Proc Natl Acad USA 1997, 94:10301-10306.
19. Rose NR, Herskowitz A, Neumann DA, Neu N: Autoimmune myocarditis: a paradigm of post-infection autoimmune disease. Immunol Today 1988, 9:117-120.
20. Wolfgram LJ, Beisel KW, Rose NR: Heart-specific autoantibodies following murine Coxsackievirus B3 myocarditis. J Exp Med 1965, 161:1112-1121.
21. Kaplan MH, Meyeserian M: An immunological cross-reaction berween Group-A Streptococcal cells and human heart tissue. Lancet 1962, 1:706-710.
22. Isenberg DA, Maddison P, Swana G, Skinner RP, Swana M, Jones M, Addison I, Dudeney C, Shall S, Roiey AEL, Shoenfeld Y: Profile of autoantibodies in the serum of patients with tuberculosis, Klebsiella and other Gram-negative infections. Clin Exp Immunol 1987, 67:516-523.
23. Vaughan JH, Valbracht JR, Nguyen MD, Handley HH, Smith RS, Patrick K, Rhodes GH: Epstein-Barr virus-induced autoimmne responses. I Immunoglobulins M autoantibodies to proteins mimicking and not mimicking Epstein-Barr Virus Nuclear Antigen 1. J Clin Invest 1995, 95:1306-1315.
24. Vaughan JH, Nguyen MD, Valbracht JR, Smith RS, Patrick K, Rhodes GH: Epstein-Barr virus-induced autoimmune responses. II Immunoglobulin G autoantibodies to mimicking and not-mimicking epitopes. Presence in autoimmune disease. J Clin Invest 1995, 95:1316-1327.
25. Bachmaier K, Neu N, de la Maza LM, Pal S, Hassel A, Penninger JM: Chlamydia infections and heart disease linked through antigenic mimicry. Science 1999, 283:1335-1339.
26. Rose NR, Bona C: Defining criteria for autoimmune diseases (Witebsky's postulates revisited). Immunol Today 1993, 14:426-430.
27. Levy P, Raoult D, Razongles JJ: Q fever and autoimmunity. Eur J Epidemiol 1989, 5:447-453.
28. Camacho MT, Outschoorn I, Téllez A: Role of IgG subclasses in Q fever. Eur J Clin Microbiol Infect Dis 1995, 14:1070-1075.
29. Camacho MT, Outschoorn I, Echevarría C, Kovachova E, Yebra M, Maté I, Auffray P, Téllez A: Distribution of IgA subclass response to C.burnetii in patients with acute and chronic Q fever. Clin Immunol Immunopathol 1998, 88:80-83.
30. Tan EM: Relationship of nuclear staining patterns with precipitating antibodies in systemic lupus erythematosus. J Lab Clin Med 1967, 70:800-812.
31. Laemmli UK: Cleavage of structural proteins during assembly of thew head of bacteriophage T4. Nature 1970, 227:680-685.
32. Garcia-Lerma JG, Mendoza AZ, Ramos MJ, Sequi J: Evaluation of Recombinant Ro/SSA, La/SSB, Sm and U1 RNP Autoantigens in Clinical Diagnosis. J Clin Lab Anal 1995, 9:52-58.
33. Scheerder I, Buyzere M, Algoed L, De Lange M, Delanghe J, Bogaert AM, Clement DL: Characteristic anti-heart antibody patterns in post-cardiac injury syndrome, endocarditis and acute myocarditis. Eur Heart J 1987, 8:237-238.
34. Caforio AL, Bonifacio E, Stewart JT, Neglia D, Parodi O, Bottazzo GF, McKenna WJ: Novel organ-specific circulating cardiac autoantibodies in dilated cardiomyopathy. J Am Coll Cardiol 1990, 15:1527-1534.
35. Caforio AL, Mahon NJ, McKenna WJ: Cardiac autoantibodies to myosin and other heart-specific autoantigens in myocarditis and dilated cardiomyopathy. Autoimmunity 2001, 34:199-204.
36. Latif N, Baker C, Dunn MJ, Rose ML, Brady P, Yacoub MH: Frequency and specificity of antiheart antibodies in patients with dilated cardiomyopathy detected using SDS-PAGE and Western-blotting. J Am Coll Cardiol 1993, 22:1378-1384.
37. Tontsch D, Pankuweit S, Maish B: Autoantibodies in the sera of patients with rheumatic heart disease: characterization of myocardial antigens by two-dimensional immunoblotting and N-terminal sequence analysis. Clin Exp Immunol 2000, 121:270-274.
38. Neu N, Rose NR, Beisel KW, Herskowitz A, Gurri-Glass G, Craig SW: Cardiac Myosin induces myocarditis in genetically predisposed mice. J Immunol 1987, 139:3630-3636.
39. Moldave K: Discovery, resolution, purification and function of elongation factors. Methods Enzymol 1990, 182:809-818.
40. Negrutskii BS, El'skaya AV: Eukaryotic translation elongation factor 1 alpha: structure, expression, functions and possible role in aminoaciyl-tRNA channelling. Prog Nucleic Acid Res Mol Biol 1998, 60:47-78.
41. Bektas M, Guncer B, Guven C, Nurten R, Bermek E: Actin-an inhibitor of eukariotic alongation factor activities. Biochem Biophys Res Commun 2004, 317:1061-1066.
42. Edmonds BT, Wyckoff J, Yeung Y, Wang Y, Stanley R, Jones J, Segall J, Condeelis J: Elongation factor-1α is an overexpressed actin binding proteins in metastatic rat mammary adenocarcinoma. J Cell Sci 1996, 109:2705-2714.
43. Khalyfa A, Carlson BM, Carlson JA, Wang E: Toxin injury-dependent switched expression between EF-1 alpha and its sister S1 in rat skeletal muscle. Dev Dyn 1999, 216:267-273.
44. Ditzel HJ, Masaki Y, Nielsen H, Farnaes L, Burton RD: Clonning and expression of a novel human antibody-antigen pair associated with Felty's syndrome. PNAS 2000, 97:9234-9239.
45. Ohkouchi K, Mizutani H, Tanaka M, Takahashi M, Nakashima K, Shimizu M: Anti-elongation factor-1α autoantibody in adult athopic dermatitis patients. Intern Immunol 1999, 11:1635-1640.