Comparison of immunnological and genotoxicological parameters in automobile emission inspectors exposed to polycyclic aromatic hydrocarbons

Environmental Toxicology and Pharmacology

Volumn 21, Issue 1, 2006, Pages 108-117

  Oh, Eunha ^a   Im, Hosub ^b   Kang, Hyung Sik ^c   Jung, Woonun ^d   Won, Nam Hee ^a   Lee, Eunil ^a,e   Sul, Donggeun ^a  

^a Korea University College of Medicine   (South Korea)

^b Korea University   (South Korea)

^c Chonnam National University   (South Korea)

^d MyGene Company   (South Korea)

^e Medical Science Research Center   (South Korea)

Author keywords

Comet assay; Emission; Immunoglobulin; Leukocytes; Polycyclic aromatic hydrocarbons

Indexed keywords

2 NAPHTHOL; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 4; MEMBRANE ANTIGEN; POLYCYCLIC AROMATIC HYDROCARBON;

ADULT; ARTICLE; CELL SUBPOPULATION; CYTOTOXIC T LYMPHOCYTE; DNA DAMAGE; EXHAUST GAS; GENOTOXICITY; HUMAN; IMMUNE STATUS; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTOXICITY; LEUKOCYTE; LYMPHOCYTE ACTIVATION; METABOLITE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; T LYMPHOCYTE; URINE;

EID: 28444492353     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2005.08.004     Document Type: Article

References (37)

1. A.K. Alexandrie, M. Warhoim, U. Carstensen, A. Axmon, L. Hagmar, J.O. Levin, C. Östman, and A. Rannung CYP1A1 and GSTM1 polymorphisms affect urinary 1-hydroxypyrene levels after PAH exposure Carcinogenesis 21 2000 669 676
2. S.W. Burchiel, W.M. Hadley, L.S. Barton, R.H. Fincher, L.D. Lauer, and J.H. Dean Persistent suppression of humoral immunity by 7,12-dimethylbenz(a) anthracene in B6C3F1 mice: correlations with changes in spleen surface markers detected by flow cytometry Int. J. Immunopharmacol. 10 1988 369 376
3. R. Crebeli, P. Carta, C. Andreoli, G. Aru, G. Dobrowolny, S. Rossi, and A. Zijno Biomonitoring of primary aluminium industry workers: detection of micronuclei and repairable DNA lesions by alkaline SCGE Mutat. Res. 516 2002 63 70
4. D.R. Davila, D.L. Romero, and S.W. Burchiel Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by alpha-naphthoflavone Toxicol. Appl. Pharmacol. 139 1996 333 341
5. A. Falahi-Ardakani Contamination of environment with heavy metals emitted from automotives Ecotoxicol. Environ. Saf. 8 1984 152 161
6. A.H. Fang, W.A. Smith, P. Vouros, and R.C. Gupta Identification and characterization of novel benzo(a)pyrene-derived DNA adduct Biophys. Res. Commun. 281 2001 383 389
7. J.A. Harrigan, C.M. Vezina, B.P. McGarrigle, N. Ersing, H.C. Box, A.E. Maccubbin, and J.R. Olson DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo(a)pyrene Toxicol. Sci. 77 2004 307 314
8. R. Jefferis, and D.S. Kumararatne Selective IgG subclass deficiency: quantification and clinical relavance Clin. Exp. Immunol. 81 2003 195 206
9. F.J. Joneneelen, Anzion RBM, C.M. Leijdekkers, R.P. Bos, and P.T. Henderson 1-Hydroxypyrene in human urine after exposure to coal tar and a coal tar derived product Int. Arch. Occup. Environ. Health 57 1985 47 55
10. F. Kassie, W. Pazefall, and S. Knasmüler Single cell gel electrophoresis assay: a new technique for human biomonitoring studies Mutat. Res. 463 2000 13 31
11. H. Kim, Y.-D. Lee, H. Lee, T. Kawamoto, M. Yang, and T. Katoh Assay of 2-naphthol in human urine by high-performance liquid chromatography J. Chromatogr. B Biomed. Appl. 734 1999 211 217
12. H. Kim, S.-H. Cho, J.-W. Kang, Y.-D. Kim, H.-M. Nam, C.-H. Lee, H. Lee, and T. Kawamoto Urinary 1-hydroxypyrene and 2-naphthol concentration in male Koreans Int. Arch. Occup. Environ. Health 74 2001 59 62
13. H.A. Kim, E.M. Kim, Y.C. Park, J.Y. Yu, S.K. Hong, S.H. Jeon, K.L. Park, S.J. Hur, and Y. Heo Immunotoxicological effects of Agent Orange exposure to the Vetnam War Korean veterans Ind. Health 41 2003 158 166
14. J.H. Kim, K.H. Stansbury, N.J. Walker, M.A. Trush, P.T. Strickland, and T.R. Sutter Methabolism of benzo(a)pyrene and benzo(a)pyrene-7,8-diol by human cytochrome P450 1B1 Carcinogenesis 18 1999 1847 1853
15. K. Kimber, K. Jones, and D.A. Vignali The influence of 7,12-dimethylbenz(a)anthracene on natural killer (NK) cell function in rats J. Clin. Lab. Immunol. 20 1986 193 198
16. S.J. Kwack, and B.M. Lee Correlation between DNA or protein adducts and benzo(a)pyrene diol epoxide I-triglyceride adduct detected in vitro and in vivo Carcinogenesis 21 2000 629 632
17. D.A. Lawrence, and MJ. McCabe Jr. Immunomodulation by metals Int. Immunopharmacol. 2 2002 293 302
18. G. Losana, L. Rigamonti, I. Borghi, B. Assenzio, S. Ariotti, E. Jouanguy, F. Altare, G. Forni, J.L. Casanova, and F. Novelli Requirement for both IL-2 and INF-γ production by human T cells Eur. J. Immunol. 32 2002 693 700
19. G. Mastlangelo, C. Veller Fornasa, S. Pavanello, G. Mercer, M. Lazzaro, G. Milan, E. Fadda, U. Fedeli, and E. Clonfero Polycyclic hydrocarbons administered in humans by dermal route increase total IgE Int. J. Immunopathol. Pharmacol. 16 2003 145 150
20. V.J. Melendez-Colon, A. Luch, A. Seidel, and W.M. Baird Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adduct rather than apurinic sites Carcinogen 20 1999 1885 1891
21. V.J. Melendez-Colon, A. Luch, A. Seidel, and W.M. Baird Formation of stable DNA adducts and apurinic sites upon metabolic activation of Bay and Fjord region polycyclic aromatic hydrocarbons in Human cell cultures Chem. Res. Toxicol. 13 2000 10 17
22. P. Meller, L.E. Knudsen, and H. Wallin The comet assay, a rapid test in biomonitoring occupational exposure to DNA-damaging agents and effect of confounding factors Cancer Epidemiol. Biomarker Prev. 9 2000 1005 1015
23. E. Merlo, A. Andreassen, and A. Weston Urinary excretion of 1-hydroxypyrene as a marker for exposure to urban air levels of polycyclic aromatic hydrocarbons Cancer Epidemiol. Biomarker Prev. 7 1998 692 696
24. K.K. Rozman, and C.D. Klasassen Casaret and Doull's toxicology Basic Sci. Poison 2001 107 132
25. B. Schoket DNA damage in human exposed to environmental and dietary polycyclic aromatic hydrocarbons Mutat. Res. 424 1999 143 153
26. N.P. Singh, M.T. McCoy, R.R. Tice, and E.L. Schnider A simple technique for quantification follow levels of DNA damage in individual cells Exp. Cell Res. 175 1988 184 191
27. D.C. Spink, B.H. Katz, M.M. Hussain, B.C. Spink, S.J. Wu, N. Liu, R. Pause, and L.S. Kaminsky Induction of CYP1A1 and CYP1B1 in T-47D human breast cancer cells by benzo(a)pyrene is diminished by arsenite Drug Metabol. Dispos. 30 2002 262 269
28. D. Sul, D. Lee, H. Im, E. Oh, J. Kim, and E. Lee Single strand DNA breaks in T- and B-lymphocytes and granulocytes in workers exposed to benzene Toxicol. Lett. 134 2002 87 95
29. D. Sul, E. Oh, H. Im, M. Yang, and E. Lee DNA damage in T-and B-lymphocytes and granulocytes in emission inspection and incineration workers exposed to polycyclic aromatic hydrocarbons Mutat. Res. 538 2003 109 119
30. The Z International Agency for Research on Cancer (IARC), IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans; polynuclear aromatic compounds, part 1, chemical, environmental and experimental data, vol. 32, 1998.
31. R.R. Tice, E. Agurell, D. Anderson, B. Burlinson, A. Hartmann, H. Kobayashi, Y. Miyamae, R. Rojas, J.C. Ryu, and Y.F. Sasaki Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing Environ. Mol. Mutagen. 35 2000 206 221
32. E.C. Ward, M.J. Murray, L.D. Lauer, R.V. House, R. Iron, and J.H. Dean Persistent suppression in humoral and cell-mediated immunity in mice following exposure to 7,12-dimethylbenz(a) anthracene Int. J. Immunopharmacol. 8 1986 13 22
33. A. Walczak-Drzewiecka, J. Wyczolkowska, and J. Dastych Environmental relevant metal and transition metal ions enhance Fc epsilon RI-mediated mast cell activation Environ. Health Perspect. 111 2003 708 713
34. N. Winker, H. Tuschl, R. Kovac, and E. Weber Immunological investigations in a group of workers exposed to various levels of polycyclic aromatic hydrocarbons J. Appl. Toxicol. 17 1996 23 29
35. C.H. Wu, C.L. Hsieh, T.Y. Song, and G.C. Yen Inhibitory effects of Cassia tora L. on benzo(a)pyrene-mediated DNA damage toward HepG2 cells J. Agric. Food Chem. 49 2001 2579 2586
36. M. Yang, M. Kaga, T. Katoh, and T. Kawamoto A study for the proper application of urinary naphthols, new biomarkers for airborne polycyclic aromatic hydrocarbons Arch. Environ. Contam. Toxicol. 36 1999 99 108
37. A.T. Yusuf, L. Vian, R. Sabatier, and J.P. Cano In vitro detection of indirect-acting genotoxins in the comet assay using HepG2 cells Mutat. Res. 468 2000 227 234