H2-M3 major histocompatibility complex class Ib-restricted CD8 T cells induced by Salmonella enterica serovar typhimurium infection recognize proteins released by Salmonella serovar typhimurium

Infection and Immunity

Volumn 73, Issue 12, 2005, Pages 8002-8008

  Ugrinovic, S ^a,c   Brooks, C G ^a   Robson, J ^a   Blacklaws, B A ^b   Hormaeche, C E ^a,b   Robinson, J H ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1 H2 M3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; FIBROBLAST; GENETIC TRANSFECTION; GRAM NEGATIVE BACTERIUM; HLA SYSTEM; MAJOR HISTOCOMPATIBILITY COMPLEX RESTRICTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA ENTERICA; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; TYPHOID FEVER;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BETA 2-MICROGLOBULIN; BONE MARROW CELLS; CELL LINE; HISTOCOMPATIBILITY ANTIGENS CLASS I; MACROPHAGES; MICE; MICE, INBRED BALB C; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM; T-LYMPHOCYTES, CYTOTOXIC;

EID: 28444471234     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.12.8002-8008.2005     Document Type: Article

References (30)

1. Byers, D. E., and K. F. Lindahl. 1998. H2-M3 presents a nonformylated viral epitope to CTLs generated In vitro. J. Immunol. 161:90-96.
2. Catic, A., G. Dietrich, I. Gentschev, W. Goebel, S. H. Kaufmann, and J. Hess. 1999. Introduction of protein or DNA delivered via recombinant Salmonella typhimurium into the major histocompatibility complex class I presentation pathway of macrophages. Microbes Infect. 1:113-121.
3. Cookson, B. T., and M. J. Bevan. 1997. Identification of a natural epitope presented by Salmonella-infected macrophages and recognized by T cells from orally immunized mice. J. Immunol. 158:4310-4319.
4. Fischer, H. G., B. Opel, K. Reske, and A. B. Reske-Kunz. 1988. Granulocyte-macrophage colony-stimulating factor-cultured bone marrow-derived macrophages reveal accessory cell function and synthesis of MHC class II determinants in the absence of external stimuli. Eur. J. Immunol. 18:1151-1158.
5. Glas, R., K. Sturmhöfel, G. J. Hämmerling, K. Kärre, and H.-G. Ljunggren. 1992. Restoration of a tumorigenic phenotype by beta 2-microglobulin transfection to EL-4 mutant cells. J. Exp. Med. 175:843-846.
6. Hamilton, S. E., B. B. Porter, K. A. Messingham, V. P. Badovinac, and J. T. Harty. 2004. MHC class Ia-restricted memory T cells inhibit expansion of a nonprotective MHC class Ib (H2-M3)-restricted memory response. Nat. Immunol. 5:159-168.
7. Hess, J., I. Gentschev, D. Miko, M. Welzel, C. Ladel, W. Goebel, and S. H. Kaufmann. 1996. Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis. Proc. Natl. Acad. Sci. USA. 93:1458-1463.
8. Hess, J., L. Grode, J. Hellwig, P. Conradt, I. Gentschev, W. Goebel, C. Ladel, and S. H. Kaufmann. 2000. Protection against murine tuberculosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the 30-kDa antigen of Mycobacterium bovis BCG. FEMS Immunol. Med. Microbiol. 27:283-289.
9. Hess, J., C. Ladel, D. Miko, and S. H. Kaufmann. 1996. Salmonella typhimurium aroA-infection in gene-targeted immunodeficient mice: major role of CD4+ TCR-alpha beta cells and IFN-gamma in bacterial clearance independent of intracellular location. J. Immunol. 156:3321-3326.
10. Hormaeche, C. E., H. S. Joysey, L. Desilva, M. Izhar, and B. A. Stocker. 1991. Immunity conferred by Aro-Salmonella live vaccines. Microb. Pathog. 10: 149-158.
11. Jones, B. D., and S. Falkow. 1996. Salmonellosis: Host immune responses and bacterial virulence determinants. Annu. Rev. Immunol. 14:533-561.
12. Kerksiek, K. M., A. Ploss, I. Leiner, D. H. Busch, and E. G. Pamer. 2003. H2-M3-restricted memory T cells: persistence and activation without expansion. J. Immunol. 170:1862-1869.
13. Lenz, L. L., and M. J. Bevan. 1996. H2-M3 restricted presentation of Listeria monocytogenes antigens. Immunol. Rev. 151:107-121.
14. Lenz, L. L., B. Dere, and M. J. Bevan. 1996. Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by H2-M3. Immunity 5:6-72.
15. Lindahl, K. F., D. E. Byers, V. M. Dabhi, R. Hovik, E. P. Jones, G. P. Smith, C. R. Wang, H. Xiao, and M. Yoshino. 1997. H2-M3, a full-service class Ib histocompatability antigen. Annu. Rev. Immunol. 15:851-879.
16. Lo, W. F., H. Ong, E. S. Metcalf, and M. J. Soloski. 1999. T-cell responses to Gram-negative intracellular bacterial pathogens: a role for CD8 T cells in immunity to Salmonella infection and the involvement of MHC class Ib molecules. J. Immunol. 162:5398-5406.
17. Lo, W. F., A. S. Woods, A. DeCloux, R. J. Cotter, E. S. Metcalf, and M. J. Soloski. 2000. Molecular mimicry mediated by MHC class Ib molecules after infection with gram-negative pathogens. Nat. Med. 6:215-218.
18. Mastroeni, P., B. Villarreal-Ramos, and C. E. Hormaeche. 1993. Adoptive transfer of immunity to oral challenge with virulent salmonellae in innately susceptible BALB/c mice requires both immune serum and T cells. Infect. Immun. 61:3981-3984.
19. Mastroeni, P., B. Villarreal-Raraos, and C. E. Hormaeche. 1992. Role of T cells, TNF alpha and IFN gamma in recall of immunity to oral challenge with virulent salmonellae in mice vaccinated with live attenuated aro-Salmonella vaccines. Microb. Pathog. 13:477-491.
20. McSorley, S. J., B. T. Cookson, and M. K. Jenkins. 2000. Characterization of CD4+ T-cell responses during natural infection with Salmonella typhimurium. J. Immunol. 164:986-993.
21. Musson, J. A., R. D. Hayward, A. A. Delvig, R. Hernan, C. E. Hormaeche, V. Koronakis, and J. H. Robinson. 2002. Processing of Salmonella typhimurium for presentation of a CD4 T-cell epitope from Salmonella invasion protein C (SipC). Eur. J. Immunol. 32:2664-2671.
22. + major histocompatibility class I-restricted cytotoxic T lymphocytes. Infect. Immun. 70:4009-4018.
23. Qimron, U., N. Madar, H.-W. Mittrücker, A. Zilka, I. Yosef, N. Bloushtain, S. H. E. Kaufmann, I. Rosenshine, R. N. Apte, and A. Porgador. 2004. Identification of Salmonella typhimurium genes responsible for interference with peptide presentation on MHC class I molecules: Dyej Salmonella mutants induce superior CD8+ T-cell responses. Cell. Microbiol. 6:1057-1070.
24. Russmann, H., H. Shams, F. Poblete, Y. Fu, J. E. Galan, and R. O. Donis. 1998. Delivery of epitopes by the Salmonella type III secretion system for vaccine development. Science 281:565-568.
25. Salerno-Goncalves, R., M. Fernandez-Vina, D. M. Lewinsohn, and M. B. Sztein. 2004. Identification of a human HLA-E-restricted CD8+ T-cell subset in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine. J. Immunol. 173:5852-5862.
26. Sinha, K., P. Mastroeni, J. Harrison, R. D. de Hormaeche, and C. E. Hormaeche. 1997. Salmonella typhimurium aroA, htrA, and aroD htrA mutants cause progressive infections in athymic (nu/nu) BALB/c mice. Infect. Immun. 65:1566-1569.
27. Sztein, M. B., M. K. Tanner, Y. Polotsky, J. M. Orenstein, and M. M. Levine. 1995. Cytotoxic T lymphocytes after oral immunization with attenuated vaccine strains of Salmonella typhi in humans. J. Immunol. 155:3987-3993.
28. Vazquez-Torres, A., J. Jones-Carson, A. J. Baumler, S. Falkow, R. Valdivia, W. Brown, M. Le, R. Berggren, W. T. Parks, and F. C. Fang. 1999. Extraintestinal dissemination of Salmonella by CD18-expressing phagocytes. Nature 401:804-808.
29. Wang, C.-R., B. E. Loveland, and K. F. Lindahl. 1991. H-2M3 encodes the MHC class I molecule presenting the maternally transmitted antigen of the mouse. Cell 66:335-345.
30. Wong, P., and E. Pamer. 2003. CD8 T-cell responses to infectious pathogens. Annu. Rev. Immunol. 21:29-70.