Selective activation of G-protein coupled receptors by volatile anesthetics

Molecular and Cellular Neuroscience

Volumn 30, Issue 4, 2005, Pages 506-512

  Peterlin, Zita ^a   Ishizawa, Yumiko ^b   Araneda, Ricardo ^a   Eckenhoff, Roderic ^b   Firestein, Stuart ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 CHLORO 1,2,2 TRIFLUOROCYCLOBUTANE; 1,2 DICHLOROHEXAFLUOROCYCLOBUTANE; 2,3 DICHLOROOCTAFLUOROBUTANE; ENFLURANE; G PROTEIN COUPLED RECEPTOR; HALOTHANE; INHALATION ANESTHETIC AGENT; ISOFLURANE; SEVOFLURANE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SUBPOPULATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; ELECTROPHYSIOLOGY; MALE; MOLECULAR PROBE; NONHUMAN; ODOR; OLFACTORY RECEPTOR; OPTICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STIMULATION;

ANESTHETICS, INHALATION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HALOTHANE; MALE; MEMBRANE POTENTIALS; OCTANOLS; ODORS; OLFACTORY MUCOSA; OLFACTORY RECEPTOR NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, ODORANT; SIGNAL TRANSDUCTION; SMELL;

ANIMALIA;

EID: 28444466936     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2005.08.012     Document Type: Article

References (40)

1. R.C. Araneda, A.D. Kini, and S. Firestein The molecular receptive range of an odorant receptor Nat. Neurosci. 3 2000 1248 1255
2. A.A. Bhattacharya, S. Curry, and N.P. Franks Binding of the general anesthetics propofol and halothane to human serum albumin. High resolution crystal structures J. Biol. Chem. 275 2000 38731 38738
3. T. Bozza, P. Feinstein, C. Zheng, and P. Mombaerts Odorant receptor expression defines functional units in the mouse olfactory system J. Neurosci. 22 2002 3033 3043
4. S. Chen, A.P. Lane, R. Bock, T. Leinders-Zufall, and F. Zufall Blocking adenylyl cyclase inhibits olfactory generator currents induced by "IP(3)-odors" J. Neurophysiol. 84 2000 575 580
5. A. Chess, I. Simon, H. Cedar, and R. Axel Allelic inactivation regulates olfactory receptor gene expression Cell 78 1994 823 834
6. Do, S.H., Kamatchi, G.L., Durieux, M.E. 2001. The effects of isoflurane on native and chimeric muscarinic acetylcholine receptors: the role of protein kinase C. Anesth. Analg. 93, 375-381 (373rd contents page).
7. R.C. Dutton, A.J. Maurer, J.M. Sonner, M.S. Fanselow, M.J. Laster, and E.I. Eger II Short-term memory resists the depressant effect of the nonimmobilizer 1-2-dichlorohexafluorocyclobutane (2N) more than long-term memory Anesth. Analg. 94 2002 631 639
8. E.I. Eger II, and M.J. Laster The effect of rigidity, shape, unsaturation, and length on the anesthetic potency of hydrocarbons Anesth. Analg. 92 2001 1477 1482
9. E.I. Eger II, M.J. Halsey, R.A. Harris, D.D. Koblin, A. Pohorille, J.C. Sewell, J.M. Sonner, and J.R. Trudell Hypothesis: volatile anesthetics produce immobility by acting on two sites approximately five carbon atoms apart Anesth. Analg. 88 1999 1395 1400
10. E.I. Eger II, Y. Xing, R. Pearce, S. Shafer, M.J. Laster, Y. Zhang, M.S. Fanselow, and J.M. Sonner Isoflurane antagonizes the capacity of flurothyl or 1,2-dichlorohexafluorocyclobutane to impair fear conditioning to context and tone Anesth. Analg. 96 2003 1010 1018
11. I. Gaillard, S. Rouquier, J.P. Pin, P. Mollard, S. Richard, C. Barnabe, J. Demaille, and D. Giorgi A single olfactory receptor specifically binds a set of odorant molecules Eur. J. Neurosci. 15 2002 409 418
12. H. Hamana, J. Hirono, M. Kizumi, and T. Sato Sensitivity-dependent hierarchical receptor codes for odors Chem. Senses 28 2003 87 104
13. C.W. Honemann, G.W. Nietgen, T. Podranski, C.K. Chan, and M.E. Durieux Influence of volatile anesthetics on thromboxane A2 signaling Anesthesiology 88 1998 440 451
14. Y. Ishizawa, R. Sharp, P.A. Liebman, and R.G. Eckenhoff Halothane binding to a G protein coupled receptor in retinal membranes by photoaffinity labeling Biochemistry 39 2000 8497 8502
15. Y. Ishizawa, R. Pidikiti, P.A. Liebman, and R.G. Eckenhoff G protein-coupled receptors as direct targets of inhaled anesthetics Mol. Pharmacol. 61 2002 945 952
16. T. Kai, K.A. Jones, and D.O. Warner Halothane attenuates calcium sensitization in airway smooth muscle by inhibiting G-proteins Anesthesiology 89 1998 1543 1552
17. K. Kajiya, K. Inaki, M. Tanaka, T. Haga, H. Kataoka, and K. Touhara Molecular bases of odor discrimination: reconstitution of olfactory receptors that recognize overlapping sets of odorants J. Neurosci. 21 2001 6018 6025
18. S. Katada, T. Hirokawa, Y. Oka, M. Suwa, and K. Touhara Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: mapping the odorant-binding site J. Neurosci. 25 2005 1806 1815
19. D.D. Koblin, B.S. Chortkoff, M.J. Laster, E.I. Eger II, M.J. Halsey, and P. Ionescu Polyhalogenated and perfluorinated compounds that disobey the Meyer-Overton hypothesis Anesth. Analg. 79 1994 1043 1048
20. M.D. Krasowski, and N.L. Harrison The actions of ether, alcohol and alkane general anaesthetics on GABAA and glycine receptors and the effects of TM2 and TM3 mutations Br. J. Pharmacol. 129 2000 731 743
21. R. Liu, and R.G. Eckenhoff Weak polar interactions confer albumin binding site selectivity for haloether anesthetics Anesthesiology 102 2005 799 805
22. A.H. Liu, X. Zhang, G.A. Stolovitzky, A. Califano, and S.J. Firestein Motif-based construction of a functional map for mammalian olfactory receptors Genomics 81 2003 443 456
23. B. Malnic, J. Hirono, T. Sato, and L.B. Buck Combinatorial receptor codes for odors Cell 96 1999 713 723
24. O. Man, Y. Gilad, and D. Lancet Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons Protein Sci. 13 2004 240 254
25. K. Minami, M. Minami, and R.A. Harris Inhibition of 5-hydroxytryptamine type 2A receptor-induced currents by n-alcohols and anesthetics J. Pharmacol. Exp. Ther. 281 1997 1136 1143
26. K. Minami, T.W. Vanderah, M. Minami, and R.A. Harris Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes Eur. J. Pharmacol. 339 1997 237 244
27. K. Minami, R.W.t. Gereau, M. Minami, S.F. Heinemann, and R.A. Harris Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes Mol. Pharmacol. 53 1998 148 156
28. G.W. Moss, S. Curry, N.P. Franks, and W.R. Lieb Mapping the polarity profiles of general anesthetic target sites using n-alkane-(alpha, omega)-diols Biochemistry 30 1991 10551 10557
29. Y. Oka, M. Omura, H. Kataoka, and K. Touhara Olfactory receptor antagonism between odorants EMBO J. 23 2004 120 126
30. S.N. Pentyala, K. Sung, A. Chowdhury, and M.J. Rebecchi Volatile anesthetics modulate the binding of guanine nucleotides to the alpha subunits of heterotrimeric GTP binding proteins Eur. J. Pharmacol. 384 1999 213 222
31. M.J. Rebecchi, and S.N. Pentyala Anaesthetic actions on other targets: protein kinase C and guanine nucleotide-binding proteins Br. J. Anaesth. 89 2002 62 78
32. J.W. Scott, and P.E. Scott-Johnson The electroolfactogram: a review of its history and uses Microsc. Res. Tech. 58 2002 152 160
33. P. Seeman, and S. Kapur Anesthetics inhibit high-affinity states of dopamine D2 and other G-linked receptors Synapse 50 2003 35 40
34. A. Shibata, K. Morita, T. Yamashita, H. Kamaya, and I. Ueda Anesthetic-protein interaction: effects of volatile anesthetics on the secondary structure of poly(l-lysine) J. Pharm. Sci. 80 1991 1037 1041
35. J. Streiff, K. Jones, W.J. Perkins, D.O. Warner, and K.A. Jones Effect of halothane on the guanosine 5′ triphosphate binding activity of G-protein alpha subunits Anesthesiology 99 2003 105 111
36. K. Touhara, S. Sengoku, K. Inaki, A. Tsuboi, J. Hirono, T. Sato, H. Sakano, and T. Haga Functional identification and reconstitution of an odorant receptor in single olfactory neurons Proc. Natl. Acad. Sci. U. S. A. 96 1999 4040 4045
37. N. Vaidehi, W.B. Floriano, R. Trabanino, S.E. Hall, P. Freddolino, E.J. Choi, G. Zamanakos, and W.A. Goddard III Prediction of structure and function of G protein-coupled receptors Proc. Natl. Acad. Sci. U. S. A. 99 2002 12622 12627
38. D.K. Vassilatis, J.G. Hohmann, H. Zeng, F. Li, J.E. Ranchalis, M.T. Mortrud, A. Brown, S.S. Rodriguez, J.R. Weller, and A.C. Wright The G protein-coupled receptor repertoires of human and mouse Proc. Natl. Acad. Sci. U. S. A. 100 2003 4903 4908
39. X. Zhang, I. Rodriguez, P. Mombaerts, and S. Firestein Odorant and vomeronasal receptor genes in two mouse genome assemblies Genomics 83 2004 802 811
40. H. Zhao, L. Ivic, J.M. Otaki, M. Hashimoto, K. Mikoshiba, and S. Firestein Functional expression of a mammalian odorant receptor Science 279 1998 237 242