Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes

European Journal of Pharmacology

Volumn 339, Issue 2-3, 1997, Pages 237-244

  Minami, Kouichiro ^a   Vanderah, Todd W ^a   Minami, Makiko ^a   Harris, R Adron ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Ethanol; Halothane; Muscarinic receptor; Protein kinase C; Xenopus oocyte

Indexed keywords

1 CHLORO 1,2,2 TRIFLUOROCYCLOBUTANE; 1,2 DICHLOROHEXAFLUOROCYCLOBUTANE; 2,3 CHLOROOCTAFLUOROBUTANE; ALCOHOL; ANESTHETIC AGENT; HALOTHANE; MUSCARINIC RECEPTOR; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL CELL; ARTICLE; DRUG EFFECT; FEMALE; IMMOBILIZATION; LEARNING; MEMORY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS;

ANESTHETICS, INHALATION; ANIMALS; ANTI-INFLAMMATORY AGENTS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; HALOTHANE; INDOLES; MALEIMIDES; OOCYTES; PROTEIN KINASE C; RECEPTORS, MUSCARINIC; XENOPUS LAEVIS;

EID: 0031588379     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01354-X     Document Type: Article

References (44)

1. Anderson G.M., Horne W.C. Activators of protein kinase C decrease serotonin transport in human platelets. Biochim. Biophys. Acta. 1137:1992;331-337.
2. Dascal N., Landau E.M., Lass Y. Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'-cyclic monophoshate. J. Physiol. 352:1984;551-574.
3. DePetrillo P.B., Swift R.M. Ethanol exposure results in a transient decrease in human platelet cAMP levels: Evidence for a protein kinase C mediated process. Alcohol Clin. Exp. Res. 16:1992;290-294.
4. A and glutamate receptors: Relation to in vivo effects. Br. J. Pharmacol. 118:1996;378-384.
5. Durieux M.E. Halothane inhibits signalling through m1 muscarinic receptors expressed in Xenopus oocytes. Anesthesiology. 82:1995;174-182.
6. Durieux M.E. Muscarinic signalling in the central nervous system. Recent developments and anesthetics implications. Anesthesiology. 84:1996;173-189.
7. Dwyer R., Bennett H.L., Eger E.I. II, Heilbron D. Effects of isoflurane and nitrous oxide in subanesthetic concentrations on memory and responsiveness in volunteers. Anesthesiology. 77:1992;888-898.
8. Fibiger H.C., Damsma G., Day J.C. Behavioral pharmacology and biochemistry of central cholinergic neurotransmission. Adv. Exp. Med. Biol. 295:1991;399-414.
9. Gonsowski C.T., Chortkoff B.S., Eger E.I. II, Bennett H.L., Weiskopf R.B. Subanesthetic concentrations of desflurane and isoflurane suppress explicit and implicit learning. Anesth. Analg. 80:1995;568-572.
10. Haga K., Kameyama K., Haga T., Kikkawa U., Shiozaki K., Uchiyama H. Phosphorylation of human m1 muscarinic acetylcholine receptors by G protein-coupled receptor kinase 2 and protein kinase C. J. Biol. Chem. 271:1996;2776-2782.
11. Harris R.A., Mihic S.J., Dildy-Mayfield J.E., Machu T.K. Actions of anesthetics on ligand-gated ion channels: Role of receptor subunit composition. FASEB J. 9:1995;1454-1462.
12. Hemmings H.C. Jr., Adamo A.I.B. Effects of halothane and propofol on purified brain protein kinase C activation. Anesthesiology. 81:1994;147-155.
13. Hemmings H.C. Jr., Adamo A.I.B. Activation of endogenous protein kinase C by halothane in synaptosomes. Anesthesiology. 84:1996;652-662.
14. Hemmings H.C. Jr., Adamo A.I.B., Hoffman M.M. Biochemical characterization of the stimulatory effects of halothane and propofol on purified brain protein kinase C. Anesth. Analg. 81:1995;1216-1222.
15. Ishihara H., Martin B.L., Brautigan D.L., Karaki H., Ozaki H., Kato Y., Fusetani N., Watabe S., Hashimoto K., Uemura D., Hartshorne D.J. Calyculin A and okadaic acid: Inhibitors of protein phosphatase activity. Biochem. Biophys. Res. Commun. 159:1989;871-877.
16. Kandel L., Chortkoff B.S., Sonner J., Laster M.J., Eger E.I. II Nonanesthetics can suppress learning. Anesth. Analg. 82:1996;321-326.
17. Kato K., Kaneko S., Nomura Y. Phorbol ester inhibition of current response and simultaneous protein phosphorylation in Xenopus oocytes injected with brain mRNA. J. Neurochem. 50:1988;766-773.
18. Kitayama S., Dohi T., Uhl G.R. Phorbol esters alter functions of the expressed dopamine transporter. Eur. J. Pharmacol. 268:1994;115-119.
19. Koblin D.D., Chortkoff B.S., Laster M.J., Eger E.I. II, Halsey M.J., Ionescu P. Title polyhalogenated and perfluorinated compounds that disobey the Meyer-Overton hypothesis. Anesth. Analg. 79:1994;1043-1048.
20. Lin L.H., Leonard S., Harris R.A. Enflurane inhibits the function of mouse and human brain phosphatidylinositol-linked acetylcholine and serotonin receptors expressed in Xenopus oocytes. Mol. Pharmacol. 43:1993;941-948.
21. Magyar J., Szabo G. Effects of volatile anesthetics on the G protein-regulated muscarinic potassium channel. Mol. Pharmacol. 50:1996;1520-1528.
22. Manzoni O.J.J., Fagni L., Pin J.P., Rassendren F., Poulat F., Sladeczek F., Bockaert J. (trans)-1-aminocyclopentyl-1,3-dicarboxylate stimulates quisqualate phosphoinositide-coupled receptors but not ionotropic glutamate receptors in striatal neurons and Xenopus oocytes. Mol. Pharmacol. 38:1990;1-6.
23. Marchall, B.E., Longnecker, D.E., 1995. General anesthetics. In: Hardman, J.G., Gilman, A.G., Limbird, L.E., (Eds.) Goodman&Gilmans the pharmacological basics of therapeutics, 9th ed. MacGraw, New York, NY, pp 307-330.
24. Mascia M.P., Machu T.K., Harris R.A. Enhancement of homomeric glycine receptor function by long-chain alcohols and anesthetics. Br. J. Pharmacol. 119:1996;1331-1336.
25. Melchior C.L., Glasky A.J., Ritzmann R.F. A low dose of ethanol impairs working memory in mice in a win-shift foraging paradigm. Alcohol. 10:1993;491-493.
26. Mihic S.J., McQuilkin S.J., Eger E.I. II, Ionescu P., Harris R.A. Potentiation of γ-aminobutyric acid type A receptor-mediated chloride currents by novel halogenated compounds correlates with their abilities to induce general anesthesia. Mol. Pharmacol. 46:1994;851-857.
27. Miller K.J., Hoffman B.J. Adenosine A3 receptors regulate serotonin transport via nitric oxide and cGMP. J. Biol. Chem. 269:1994;27351-27356.
28. Minami K., Minami M., Harris R.A. Inhibition of 5-hydroxytryptamine type 2A receptor-induced currents by alcohols and anesthetics in Xenopus oocyte. J. Pharmacol. Exp. Ther. 281:1997;1136-1143.
29. Moran O., Dascal N. Protein kinase C modulates neurotransmitter response in Xenopus oocytes injected with rat brain RNA. Mol. Brain. Res. 5:1989;193-202.
30. Nabeshima T., Tohyama K., Kameyama T. Effects of DM-9384, a pyrrolidone derivative, on alcohol- and chlordiazepoxide-induced amnesia in mice. Pharmacol. Biochem. Behav. 36:1990;233-236.
31. Pritchett D.B., Bach A.W.J., Wozny M., Tabel O., Toso R.D., Shin J.C., Seeburg P.H. Structure and functional expression of cloned rat serotonin 5HT-2 receptor. EMBO. J. 7:1988;4135-4140.
32. Qian Y., Galli A., Ramamoorythy S., Risso S., Defelice L.J., Blakely R.D. Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression. J. Neurosci. 17:1997;45-57.
33. Sakuta H., Sekiguchi M., Okamoto K., Sakai Y. Oscillatory muscarinic acetylcholine responses of Xenopus oocytes are desensitized by protein kinase C and sensitized by protein phosphatase 2B. Eur. J. Pharmacol. 208:1991;297-305.
34. 1 G protein-linked receptors in Xenopus oocytes expressing brain mRNA: Role of protein kinase C. Mol. Pharmacol. 45:1994;1004-1012.
35. Singer D.R., Boton R., Maran O., Dascal N. Short- and long-term desensitization of serotonin response in Xenopus oocyte injected with brain RNA: Roles for inositol 1,4,5-triphosphate and protein kinase C. Pflug. Arch. 416:1990;7-16.
36. Skwish S., Shain W. Ethanol and diolein stimulate PKC translocation in astroglial cells. Life Sci. 47:1990;1037-1042.
37. Slater S.J., Cox K.J.A., Lombardi J.V., Ho C., Kelly M.B., Rubin E., Stubbus C.D. Inhibition of protein kinase C by alcohols and anesthetics. Nature. 364:1993;82-84.
38. Snutch T.P. The use of Xenopus oocytes to probe synaptic communication. Trends Neurosci. 11:1988;250-256.
39. 2+ ion concentration. Biochim. Biophys. Acta. 1091:1991;401-404.
40. Tobin A.B., Keys B., Nahorski S.R. Identification of novel receptor kinase that phosphorylates a phospholipase C-linked muscarinic receptor. J. Biol. Chem. 271:1996;3907-3916.
41. Toullec D., Pianetti P., Coste H., Bellevergue P., Grand-Perret T., Ajakane M., Baudet V., Boissin P., Boursier E., Loriolle F., Duhamel L., Charon D., Kirilovsky J. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J. Biol. Chem. 266:1991;15771-15781.
42. Tsuchiya M., Okimasu E., Ueda W., Hirakawa M., Utsumi K. Halothane, an inhalation anesthetic, activates protein kinase C and superoxide generation by neutrophils. FEBS. Lett. 242:1988;101-105.
43. Tuominen R.K., Lusting S., Mannisto P.T., Viluksela M. Ethanol activates protein kinase C (PKC) in cultured bovine adrenal medullary (BAM) chromaffin cells. Soc. Neurosci. Abstr. 18:1992;283.
44. Vasilets L.A., Schmalzing G., Madefessel K., Haase W., Schwarz W. Activation of protein kinase C by phorbol ester induces downregulation of the Na+/K(+)-ATPase in oocytes of Xenopus laevis. J. Memb. Biol. 118:1990;131-142.